Compounds > 3-methyl-s-triazolo(3,4-a)phthalazine
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3-methyl-s-triazolo(3,4-a)phthalazine and hydralazine

3-methyl-s-triazolo(3,4-a)phthalazine has been researched along with hydralazine in 5 studies

*Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent. [MeSH]

*Hydralazine: A direct-acting vasodilator that is used as an antihypertensive agent. [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iwaki, M; Ogiso, T; Ohtsuki, N1
Juni, K; Nakano, M; Tomitsuka, T1
Lin, MS; Ludden, TM; McNay, JL; Shepherd, AM1
Facchini, V; Harland, SJ; Timbrell, JA1
Lemke, LE; McQueen, CA1

Other Studies

5 other study(ies) available for 3-methyl-s-triazolo(3,4-a)phthalazine and hydralazine

ArticleYear
Pharmacokinetics of formation and excretion of some metabolites of hydralazine and their hypotensive effect in rats.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:2

    Topics: Animals; Blood Pressure; Hydralazine; Hydrazones; In Vitro Techniques; Kinetics; Male; Phthalazines; Rats; Rats, Inbred Strains

1985
Identification of the decomposition products of hydralazine hydrazones with three endogenous ketones and kinetic study of the formation of 3-methyl-s-triazolo[3,4,a]phthalazine from hydralazine and pyruvic acid].
    Chemical & pharmaceutical bulletin, 1980, Volume: 28, Issue:11

    Topics: Chemical Phenomena; Chemistry; Humans; Hydralazine; Hydrazones; Ketones; Kinetics; Phthalazines; Pyridazines; Pyruvates; Triazoles

1980
Variability of plasma hydralazine concentrations in male hypertensive patients.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acetylation; Aged; Biological Availability; Dose-Response Relationship, Drug; Humans; Hydralazine; Hydrazones; Hypertension; Liver; Male; Middle Aged; Phthalazines; Pyruvates; Time Factors; Triazoles

1981
Effect of dose on acetylator phenotype distribution of hydralazine.
    Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:3

    Topics: Acetylation; Dose-Response Relationship, Drug; Humans; Hydralazine; Phenotype; Phthalazines; Triazoles

1981
Acetylation and its role in the mutagenicity of the antihypertensive agent hydralazine.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Acetylation; Animals; Antihypertensive Agents; Arylamine N-Acetyltransferase; Biotransformation; Codon; Hydralazine; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mutagenicity Tests; Mutagens; Mutation; Phthalazines; Salmonella

1995