3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole has been researched along with methylphenidate in 5 studies
| Studies (3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole) | Trials (3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole) | Recent Studies (post-2010) (3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole) | Studies (methylphenidate) | Trials (methylphenidate) | Recent Studies (post-2010) (methylphenidate) |
|---|---|---|---|---|---|
| 68 | 2 | 18 | 7,783 | 1,698 | 2,693 |
| Protein | Taxonomy | 3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (IC50) | methylphenidate (IC50) |
|---|---|---|---|
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.061 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.083 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.1 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.079 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Decker, MW; McGaughy, J; Sarter, M | 1 |
| Horrigan, JP | 1 |
| Bennani, YL; Black, LA; Decker, MW; Esbenshade, TA; Faghih, R; Fox, GB; Hancock, AA; Pan, JB | 1 |
| Franke, AG; Huss, M; Konrad, A; Lieb, K | 1 |
| Guo, L; Guo, T; Liu, K; Yang, C | 1 |
2 review(s) available for 3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole and methylphenidate
| Article | Year |
|---|---|
Present and future pharmacotherapeutic options for adult attention deficit/hyperactivity disorder.
Topics: Adult; Amphetamines; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Donepezil; Dopamine Plasma Membrane Transport Proteins; Humans; Indans; Isoxazoles; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Piperidines; Pyrrolidines | 2001 |
[Stimulant and non-stimulant medication in current and future therapy for ADHD].
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Amphetamines; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Benzhydryl Compounds; Central Nervous System Stimulants; Child; Dextroamphetamine; Fatty Acids, Omega-3; Guanfacine; Histamine Agonists; Humans; Isoxazoles; Lisdexamfetamine Dimesylate; Memantine; Methylphenidate; Modafinil; Off-Label Use; Propylamines; Pyridines; Pyrrolidines; Receptors, AMPA | 2012 |
3 other study(ies) available for 3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole and methylphenidate
| Article | Year |
|---|---|
Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats.
Topics: Animals; Attention; Behavior, Animal; Central Nervous System Stimulants; Isoxazoles; Male; Methylphenidate; Nootropic Agents; Prosencephalon; Pyrrolidines; Rats; Rats, Inbred F344; Receptors, Nicotinic | 1999 |
Effects of histamine H(3) receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup.
Topics: Animals; Anti-Anxiety Agents; Arousal; Attention Deficit Disorder with Hyperactivity; Avoidance Learning; Central Nervous System Stimulants; Cognition Disorders; Disease Models, Animal; Histamine Antagonists; Imidazoles; Impulsive Behavior; Isoxazoles; Ligands; Male; Methylphenidate; Motor Activity; Nicotinic Agonists; Psychomotor Performance; Pyrrolidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Histamine H3 | 2002 |
A comparative study of the effects of ABT-418 and methylphenidate on spatial memory in an animal model of ADHD.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Disease Models, Animal; Immunohistochemistry; Isoxazoles; Male; Maze Learning; Memory; Methylphenidate; Nicotinic Agonists; Pyrrolidines; Rats; Rats, Inbred SHR; Receptors, Nicotinic | 2012 |