Compounds > 3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole
Page last updated: 2024-09-03

3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole and maprotiline

3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole has been researched along with maprotiline in 1 studies

Compound Research Comparison

Studies
(3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole)		Trials
(3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole)		Recent Studies (post-2010)
(3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole)		Studies
(maprotiline)		Trials
(maprotiline)		Recent Studies (post-2010) (maprotiline)
6821893321159

Protein Interaction Comparison

ProteinTaxonomy3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (IC50)maprotiline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.078
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.03
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.927
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.413
Cytochrome P450 3A4Homo sapiens (human)4.322
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.16
Alpha-2A adrenergic receptorHomo sapiens (human)1.824
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.593
D(2) dopamine receptorHomo sapiens (human)3.463
Alpha-2B adrenergic receptorHomo sapiens (human)0.292
Alpha-2C adrenergic receptorHomo sapiens (human)3.044
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.473
D(1A) dopamine receptorHomo sapiens (human)0.373
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.03
Histamine H2 receptorHomo sapiens (human)0.4
Alpha-1D adrenergic receptorHomo sapiens (human)0.397
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.064
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.078
Histamine H1 receptorHomo sapiens (human)0.0088
D(3) dopamine receptorHomo sapiens (human)0.645
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.336
5-hydroxytryptamine receptor 6Homo sapiens (human)0.892
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)10
Sodium-dependent dopamine transporter Homo sapiens (human)2.91

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bubl, B; Feuerstein, TJ; Hubbe, U; Huethe, F; Jackisch, R; Löffler, M; McIntosh, JM1

Other Studies

1 other study(ies) available for 3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole and maprotiline

ArticleYear
Dopamine release in human neocortical slices: characterization of inhibitory autoreceptors and of nicotinic acetylcholine receptor-evoked release.
    Brain research bulletin, 2006, Jan-30, Volume: 68, Issue:5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adolescent; Adult; Aged; Alkaloids; Analysis of Variance; Animals; Autoreceptors; Azocines; Calcium; Child; Child, Preschool; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Feedback; Female; Fluvoxamine; Humans; In Vitro Techniques; Isoxazoles; Male; Maprotiline; Mice; Middle Aged; Neocortex; Nicotine; Nicotinic Antagonists; Potassium; Pyrrolidines; Quinolizines; Rats; Receptors, Nicotinic; Sulpiride; Time Factors; Tritium

2006