3-methyl-4',6-dihydroxy-3',5'-dibromoflavone has been researched along with thyroxine in 11 studies
| Studies (3-methyl-4',6-dihydroxy-3',5'-dibromoflavone) | Trials (3-methyl-4',6-dihydroxy-3',5'-dibromoflavone) | Recent Studies (post-2010) (3-methyl-4',6-dihydroxy-3',5'-dibromoflavone) | Studies (thyroxine) | Trials (thyroxine) | Recent Studies (post-2010) (thyroxine) |
|---|---|---|---|---|---|
| 13 | 0 | 0 | 38,989 | 1,410 | 6,550 |
| Protein | Taxonomy | 3-methyl-4',6-dihydroxy-3',5'-dibromoflavone (IC50) | thyroxine (IC50) |
|---|---|---|---|
| Transthyretin | Homo sapiens (human) | 2.1939 | |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | 5.25 | |
| Solute carrier organic anion transporter family member 4C1 | Homo sapiens (human) | 8 | |
| Bile acid receptor | Homo sapiens (human) | 7.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 10 (90.91) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalieri, RR; Köhrle, J; Mendel, CM | 1 |
| Alex, S; Braverman, LE; Chanoine, JP; Fang, SL; Körhle, J; Leonard, JL; Stone, S | 1 |
| Köhrle, J; Schröder-van der Elst, JP; van der Heide, D | 1 |
| Abend, SL; Alex, S; Braverman, LE; Fang, SL; Leonard, JL | 1 |
| Hesch, RD; Irmscher, K; Köhrle, J; Spanka, M | 2 |
| Alex, S; Braverman, LE; Fang, SL; Irmscher, K; Köhrle, J; Lueprasitsakul, W; Pino, S | 1 |
| Benson, MD; Cody, V; Liepnieks, JJ; Moses, AC; Murrell, JR; Rosen, HN | 1 |
| Kennedy, JA; Lim, CF; Loidl, NM; Stockigt, JR; Topliss, DJ | 1 |
| Asunción, M; Calvo, R; Escobar del Rey, F; Morreale de Escobar, GM; Obregón, MJ; Pedraza, P | 1 |
| Köhrle, J; Morreale de Escobar, G; Rokos, H; Schröder-van der Elst, JP; van der Heide, D | 1 |
11 other study(ies) available for 3-methyl-4',6-dihydroxy-3',5'-dibromoflavone and thyroxine
| Article | Year |
|---|---|
Thyroxine (T4) transport and distribution in rats treated with EMD 21388, a synthetic flavonoid that displaces T4 from transthyretin.
Topics: Animals; Biological Transport; Brain Chemistry; Flavonoids; Injections, Intraperitoneal; Iodide Peroxidase; Iodine Radioisotopes; Kidney; Liver; Male; Prealbumin; Rats; Rats, Inbred Strains; Thyroxine | 1992 |
Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain.
Topics: Animals; Blood-Brain Barrier; Brain; Choroid Plexus; Female; Flavonoids; Humans; Iodide Peroxidase; Iodine Radioisotopes; Prealbumin; Rats; Rats, Inbred Strains; Serum Albumin; Thyroxine | 1992 |
In vivo effects of flavonoid EMD 21388 on thyroid hormone secretion and metabolism in rats.
Topics: Adipose Tissue, Brown; Animals; Brain; Chromatography, High Pressure Liquid; Flavonoids; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Thyroid Gland; Thyroxine; Tissue Distribution; Triiodothyronine; Triiodothyronine, Reverse | 1991 |
Rapid alteration in circulating free thyroxine modulates pituitary type II 5' deiodinase and basal thyrotropin secretion in the rat.
Topics: Animals; Flavonoids; Iodide Peroxidase; Male; Pituitary Gland; Prealbumin; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
5'-Deiodination in rat hepatocytes: effects of specific flavonoid inhibitors.
Topics: Animals; Benzofurans; Cell Survival; Chemical Phenomena; Chemistry; Flavonoids; Iodide Peroxidase; Iodine; Liver; Rats; Structure-Activity Relationship; Thyroxine; Triiodothyronine | 1990 |
Flavonoid administration immediately displaces thyroxine (T4) from serum transthyretin, increases serum free T4, and decreases serum thyrotropin in the rat.
Topics: Animals; Flavonoids; Iodide Peroxidase; Iodine Radioisotopes; Kinetics; Male; Prealbumin; Rats; Rats, Inbred Strains; Thyrotropin; Thyroxine | 1990 |
Flavonoid effects on transport, metabolism and action of thyroid hormones.
Topics: Animals; Binding Sites; Binding, Competitive; Flavonoids; In Vitro Techniques; Iodide Peroxidase; Liver; Male; Microsomes, Liver; Models, Biological; Models, Molecular; Rats; Structure-Activity Relationship; Thyroid Hormones; Thyroidectomy; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1988 |
Threonine for alanine substitution at position 109 of transthyretin differentially alters human transthyretin's affinity for iodothyronines.
Topics: Alanine; Amino Acid Sequence; Binding, Competitive; Escherichia coli; Flavonoids; Humans; Point Mutation; Prealbumin; Recombinant Proteins; Stereoisomerism; Threonine; Thyroxine; Triiodothyronine | 1994 |
Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Diuretics; Enzyme Inhibitors; Flavonoids; Iodide Peroxidase; Iodine Radioisotopes; Male; Phenytoin; Pituitary Gland, Anterior; Rats; Rats, Wistar; Serum Albumin, Bovine; Thyroxine; Triiodothyronine | 1996 |
Displacement of T4 from transthyretin by the synthetic flavonoid EMD 21388 results in increased production of T3 from T4 in rat dams and fetuses.
Topics: Adipose Tissue, Brown; Animals; Binding, Competitive; Brain; Enzyme Inhibitors; Female; Fetus; Flavonoids; Infusions, Intravenous; Iodide Peroxidase; Liver; Lung; Mammary Glands, Animal; Maternal-Fetal Exchange; Methimazole; Myocardium; Placenta; Prealbumin; Pregnancy; Pregnancy, Animal; Radioimmunoassay; Rats; Rats, Wistar; Thyroid Gland; Thyroxine; Triiodothyronine | 1996 |
Different tissue distribution, elimination, and kinetics of thyroxine and its conformational analog, the synthetic flavonoid EMD 49209 in the rat.
Topics: Animals; Enzyme Inhibitors; Female; Flavonoids; Iodide Peroxidase; Rats; Rats, Wistar; Thyroxine; Tissue Distribution | 1997 |