Compounds > 3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid
Page last updated: 2024-09-03

3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid and aspirin

3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid has been researched along with aspirin in 6 studies

Compound Research Comparison

Studies
(3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid)		Trials
(3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid)		Recent Studies (post-2010)
(3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid)		Studies
(aspirin)		Trials
(aspirin)		Recent Studies (post-2010) (aspirin)
361148,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomy3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Colgan, SP; Grauer, GF; Rose, BJ; Thrall, MA; Toolan, L1
Cooper, AD; Fann, JI; Kosek, JC; Loveday, M; May, K; Sarris, GE; Smith, DL; Sokoloff, MH; Stephens, RJ; Willis, AL1
Ambler, J; Butler, KD; Butler, PA; Shand, RA; Wallis, RB1
Bearn, PE; Bull, H; Marston, A; McCollum, CN; Seddon, AM1
Bearn, PE; Bull, H; Fox, B; Marston, A; McCollum, CN; Moffat, C; Seddon, AM1
Belzer, FO; Saunder, A; Schilling, M; Southard, JH1

Other Studies

6 other study(ies) available for 3-methyl-2-(3-pyridyl)-1-indoleoctanoic acid and aspirin

ArticleYear
Effects of low-dose aspirin and specific thromboxane synthetase inhibition on whole blood platelet aggregation and adenosine triphosphate secretion in healthy dogs.
    American journal of veterinary research, 1992, Volume: 53, Issue:9

    Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Dogs; Electric Impedance; Female; Platelet Aggregation; Platelet Count; Pyridines; Thromboxane-A Synthase

1992
Mechanisms responsible for inhibition of vein-graft arteriosclerosis by fish oil.
    Circulation, 1989, Volume: 80, Issue:3 Pt 1

    Topics: Animals; Arteriosclerosis; Aspirin; Carotid Arteries; Dogs; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Femoral Artery; Femoral Vein; Fish Oils; Graft Occlusion, Vascular; Hypercholesterolemia; Liver; Male; Pyridines; Thromboxane-A Synthase

1989
Prolongation of platelet survival in hypercholesterolaemic rabbits by CGS 12970 (3-methyl-2-(3-pyridyl)-1 indoleoctanoic acid) and dazoxiben.
    Thrombosis research, 1987, Mar-15, Volume: 45, Issue:6

    Topics: Animals; Aspirin; Blood Platelets; Cell Survival; Cholesterol, Dietary; Cyclooxygenase Inhibitors; Hypercholesterolemia; Imidazoles; Pyridines; Rabbits; Sulfinpyrazone; Thromboxane B2; Thromboxane-A Synthase

1987
The effect of platelet inhibitory therapy on graft thromboresistance.
    International journal of experimental pathology, 1993, Volume: 74, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusion, Vascular; Pyridines; Radiography; Random Allocation; Thromboxane-A Synthase

1993
The effect of platelet inhibitory therapy on prosthetic graft maturation.
    International journal of experimental pathology, 1993, Volume: 74, Issue:1

    Topics: Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Dogs; Drug Therapy, Combination; Female; Femoral Artery; Graft Occlusion, Vascular; Graft Survival; Platelet Aggregation Inhibitors; Pyridines; Thromboxane-A Synthase

1993
Long-term renal preservation and prevention of acute tubular necrosis by inhibition of arachidonate metabolism.
    Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera, 1995, Issue:4

    Topics: Adenosine; Allopurinol; Animals; Arachidonic Acid; Aspirin; Benzofurans; Dogs; Enzyme Inhibitors; Female; Glutathione; Ibuprofen; Imidazoles; Insulin; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Kidney Tubules; Leukotriene Antagonists; Leukotrienes; Organ Preservation; Organ Preservation Solutions; Pyridines; Raffinose; Thromboxane-A Synthase

1995