Page last updated: 2024-09-03

3-iodopindolol and isoproterenol

3-iodopindolol has been researched along with isoproterenol in 39 studies

Compound Research Comparison

Studies
(3-iodopindolol)
Trials
(3-iodopindolol)
Recent Studies (post-2010)
(3-iodopindolol)
Studies
(isoproterenol)
Trials
(isoproterenol)
Recent Studies (post-2010) (isoproterenol)
940030,7808032,640

Protein Interaction Comparison

ProteinTaxonomy3-iodopindolol (IC50)isoproterenol (IC50)
Beta-2 adrenergic receptorHomo sapiens (human)0.246
Beta-1 adrenergic receptorHomo sapiens (human)0.333
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)1.77
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.2125
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.6667

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199028 (71.79)18.7374
1990's10 (25.64)18.2507
2000's1 (2.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kirby, CR; Tischler, ME; Woodman, CR; Woolridge, D1
Kurz, JB; Perkins, JP1
Jensen, RT; Maton, PN; Zhang, L1
Areso, P; Frazer, A; Gambarana, C; Hensler, JG; Ordway, GA1
Arango, V; Ernsberger, P; Mann, JJ; Reis, DJ1
Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Uemura, N1
Rigby, JW; Wood, AJ1
Porsius, AJ; te Biesebeek, JD; van der Wouw, PA; van Rooij, HH; Vleeming, W; Wemer, J1
Christy, JP; Feldman, RD; Harrison, DG; Paul, ST1
Frazer, A; Ordway, GA1
Gonzalez-Brito, A; Guerrero, JM; Jones, DJ; Menendez-Pelaez, A; Reiter, RJ; Santana, C1
Frazer, A; Gambarana, C; Ordway, GA1
Abramson, SN; Barrett, DA; Harden, TK; Hughes, AR; Martin, MW; Molinoff, PB; Neve, KA1
Kim, D; Lachance, D; Marsh, JD1
Barrett, DA; Molinoff, PB; Neve, KA1
Liang, BT; Molinoff, PB1
Feldman, RD; Motulsky, HJ; Thede-Reynolds, KR1
Bier-Laning, CM; Gerber, JG; Miller, JA; Nies, AS; Parker, DC; Zahniser, NR1
Marsh, JD; Smith, TW1
Kierszenbaum, AL; Perkins, JP; Spruill, WA; Tres, LL; White, MG1
Frazer, A; O'Donnell, JM1
Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP1
Aronstam, RS; Kirby, ML; Stewart, DE1
Molinoff, PB; Neve, KA1
Dax, EM; Gregerman, RI; Partilla, JS; PiƱeyro, MA1
Abramson, SN; Molinoff, PB; Shorr, RG1
Linden, J; Patel, A; Spanier, AM; Weglicki, WB1
Barovsky, K; Brooker, G1
Perkins, JP; Toews, ML1
Abramson, SN; Molinoff, PB1
Birnbaumer, L; Entman, ML; Ezrailson, EG; Garber, AJ; Munson, PJ; Swartz, TL1
McCarthy, KD1
Hertel, C; Perkins, JP; Staehelin, M1
Toews, ML; Zhu, SJ1
Davis, DJ; Lefebvre, CA; Lyon, ME1
Collins, PL; Maguire, ME; Moore, JJ; Moore, RM; Roberts, JM; Zink, E1
Pantuck, CB; Smiley, RM1
Lemoine, H; Teschemacher, A1
Gurdal, H; Onaran, HO1

Other Studies

39 other study(ies) available for 3-iodopindolol and isoproterenol

ArticleYear
Cyclic adenosine monophosphate accumulation and beta-adrenergic binding in unweighted and denervated rat soleus muscle.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:7

    Topics: Animals; Cyclic AMP; Female; In Vitro Techniques; Insulin; Isoproterenol; Muscle Denervation; Muscles; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1992
Isoproterenol-initiated beta-adrenergic receptor diacytosis in cultured cells.
    Molecular pharmacology, 1992, Volume: 41, Issue:2

    Topics: Adrenergic beta-Antagonists; Astrocytoma; Cell Membrane; Half-Life; Humans; Iodine Radioisotopes; Isoproterenol; Kinetics; Pindolol; Receptors, Adrenergic, beta; Tumor Cells, Cultured

1992
Characterization of beta-adrenoreceptors on smooth muscle cells from guinea pig stomach.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding, Competitive; Carbachol; Cyclic AMP; Epinephrine; Guinea Pigs; In Vitro Techniques; Isoproterenol; Kinetics; Muscle Contraction; Muscle, Smooth; Norepinephrine; Pindolol; Receptors, Adrenergic, beta; Stomach

1990
Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Desipramine; Dihydroalprenolol; Isoproterenol; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin

1991
Demonstration of high- and low-affinity beta-adrenergic receptors in slide-mounted sections of rat and human brain.
    Brain research, 1990, May-14, Volume: 516, Issue:1

    Topics: Animals; Binding, Competitive; Brain; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Pindolol; Rats; Receptors, Adrenergic, beta

1990
125I-iodopindolol binding to frog esophageal peptic cells. Detection of amine uptake and beta-adrenergic receptors coupled to pepsinogen secretion.
    Biochemical pharmacology, 1989, May-01, Volume: 38, Issue:9

    Topics: Animals; Biogenic Amines; Biological Transport; Epinephrine; Erythrocytes; Esophagus; Hydrogen-Ion Concentration; In Vitro Techniques; Isoproterenol; Pepsinogens; Pindolol; Rana catesbeiana; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate

1989
Use of N-ethylmaleimide to directly determine the proportion of beta-adrenergic receptors exhibiting high affinity for agonists on human mononuclear leukocyte membranes.
    Biochemical pharmacology, 1989, Sep-01, Volume: 38, Issue:17

    Topics: Binding, Competitive; Cell Membrane; Ethylmaleimide; Humans; In Vitro Techniques; Isoproterenol; Leukocytes, Mononuclear; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta

1989
Density of beta adrenoceptors in rat heart and lymphocytes 48 hours and 7 days after acute myocardial infarction.
    Cardiovascular research, 1989, Volume: 23, Issue:10

    Topics: Animals; Cell Membrane; Dobutamine; Heart; Heart Ventricles; Isoproterenol; Lymphocytes; Male; Myocardial Infarction; Myocardium; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Time Factors

1989
Beta-adrenergic receptors on canine coronary collateral vessels: characterization and function.
    The American journal of physiology, 1989, Volume: 257, Issue:5 Pt 2

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Autoradiography; Collateral Circulation; Coronary Vessels; Dogs; In Vitro Techniques; Isoproterenol; Pindolol; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta

1989
Effects of prenalterol on beta adrenergic responsiveness and receptors in the cerebral cortex of the rat.
    Neuropharmacology, 1988, Volume: 27, Issue:5

    Topics: Animals; Brain; Cerebral Cortex; Cyclic AMP; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Male; Pindolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1988
Darkness-induced changes in noradrenergic input determine the 24 hour variation in beta-adrenergic receptor density in the rat pineal gland: in vivo physiological and pharmacological evidence.
    Life sciences, 1988, Volume: 43, Issue:8

    Topics: Animals; Circadian Rhythm; Darkness; Desipramine; Ganglia, Sympathetic; Isoproterenol; Male; Norepinephrine; Pindolol; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1988
Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Animals; Autoradiography; Brain Chemistry; Desipramine; Isoproterenol; Male; Norepinephrine; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1988
Interaction of beta-adrenergic receptors with the inhibitory guanine nucleotide-binding protein of adenylate cyclase in membranes prepared from cyc- S49 lymphoma cells.
    Biochemical pharmacology, 1988, Nov-15, Volume: 37, Issue:22

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; GTP-Binding Proteins; Isoproterenol; Lymphoma; Membranes; Molecular Weight; NAD; Pertussis Toxin; Pindolol; Receptors, Adrenergic, beta; Virulence Factors, Bordetella

1988
Mechanisms of beta-adrenergic receptor regulation in cultured chick heart cells. Role of cytoskeleton function and protein synthesis.
    Circulation research, 1985, Volume: 57, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Cytoskeletal Proteins; Cytoskeleton; Dose-Response Relationship, Drug; Isoproterenol; Myocardial Contraction; Pindolol; Receptors, Adrenergic, beta; Ventricular Function

1985
Selective regulation of beta-1 and beta-2 adrenergic receptors by atypical agonists.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Celiprolol; Cells, Cultured; Glioma; Guanosine Triphosphate; Iodine Radioisotopes; Isoproterenol; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta

1985
Beta adrenergic receptor subtypes in the atria: evidence for close coupling of beta-1 and beta-2 adrenergic receptors to adenylate cyclase.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alprenolol; Animals; Computers; Dogs; Dose-Response Relationship, Drug; Heart Atria; In Vitro Techniques; Iodine Radioisotopes; Isoproterenol; Myocardium; Norepinephrine; Pindolol; Receptors, Adrenergic, beta

1986
Temperature-dependent binding of hydrophilic beta-adrenergic receptor ligands to intact human lymphocytes.
    Life sciences, 1986, Oct-13, Volume: 39, Issue:15

    Topics: Adolescent; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Binding, Competitive; Cell Membrane; Humans; In Vitro Techniques; Isoproterenol; Ligands; Lymphocytes; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Temperature

1986
Comparison between the effects of aging on antagonist and agonist interactions with beta-adrenergic receptors on human mononuclear and polymorphonuclear leukocyte membranes.
    Journal of gerontology, 1988, Volume: 43, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Drug Interactions; Female; Guanosine Triphosphate; Humans; Isoproterenol; Leukocytes, Mononuclear; Male; Middle Aged; Neutrophils; Pindolol; Receptors, Adrenergic, beta

1988
Receptors for beta-adrenergic agonists in cultured chick ventricular cells. Relationship between agonist binding and physiologic effect.
    Molecular pharmacology, 1985, Volume: 27, Issue:1

    Topics: Alprenolol; Animals; Cells, Cultured; Chick Embryo; Guanylyl Imidodiphosphate; Heart Ventricles; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Pindolol; Propranolol; Receptors, Adrenergic, beta

1985
Rat Sertoli cells acquire a beta-adrenergic response during primary culture.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:7

    Topics: Animals; Cells, Cultured; Follicle Stimulating Hormone; In Vitro Techniques; Isoproterenol; Male; Phosphorylation; Pindolol; Proteins; Rats; Receptors, Adrenergic, beta; Seminiferous Tubules; Sertoli Cells

1985
Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1

    Topics: Animals; Antidepressive Agents; Cerebral Cortex; Clenbuterol; Ethanolamines; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Isoproterenol; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta

1985
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Inositol; Iodine Radioisotopes; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction; Myocardium; Organ Size; Phenethylamines; Pindolol; Procaterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetralones; Vas Deferens; Yohimbine

1985
Regulation of beta-adrenergic receptor density in the non-innervated and denervated embryonic chick heart.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:5

    Topics: Animals; Binding, Competitive; Chick Embryo; Denervation; Heart Conduction System; Isoproterenol; Kinetics; Myocardium; Pindolol; Prazosin; Propranolol; Receptors, Adrenergic, beta; Yohimbine

1986
Turnover of beta 1- and beta 2-adrenergic receptors after down-regulation or irreversible blockade.
    Molecular pharmacology, 1986, Volume: 30, Issue:2

    Topics: Animals; Cell Line; Cell Membrane; Cycloheximide; Glioma; Iodocyanopindolol; Isoproterenol; Kinetics; Muscles; Pindolol; Quinolines; Rats; Receptors, Adrenergic, beta

1986
Beta-adrenergic receptors, glucagon receptors, and their relationship to adenylate cyclase in rat liver during aging.
    Endocrinology, 1987, Volume: 120, Issue:4

    Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Glucagon; Guanine Nucleotides; Guanylyl Imidodiphosphate; Isoproterenol; Liver; Male; Pindolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Sodium Fluoride

1987
Interactions of beta-adrenergic receptors with a membrane protein other than the stimulatory guanine nucleotide-binding protein.
    Biochemical pharmacology, 1987, Jul-15, Volume: 36, Issue:14

    Topics: Adenylyl Cyclases; Animals; Cell Line; GTP-Binding Proteins; Isoproterenol; Lymphoma; Membrane Proteins; Neoplasm Proteins; Pindolol; Protein Binding; Rats; Receptors, Adrenergic, beta

1987
Rapid agonist-induced decrease of 125I-pindolol binding to beta-adrenergic receptors. Relationship to desensitization of cyclic AMP accumulation in intact heart cells.
    The Journal of biological chemistry, 1984, Dec-25, Volume: 259, Issue:24

    Topics: Animals; Binding, Competitive; Cell Membrane; Cells, Cultured; Chick Embryo; Cyclic AMP; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Pindolol; Receptors, Adrenergic, beta

1984
(-)-[125I]-iodopindolol, a new highly selective radioiodinated beta-adrenergic receptor antagonist: measurement of beta-receptors on intact rat astrocytoma cells.
    Journal of cyclic nucleotide research, 1980, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding Sites; Cells, Cultured; Iodine Radioisotopes; Isoproterenol; Isotope Labeling; Mass Spectrometry; Pindolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism

1980
Agonist-induced changes in beta-adrenergic receptors on intact cells.
    The Journal of biological chemistry, 1984, Feb-25, Volume: 259, Issue:4

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytoma; Binding, Competitive; Cell Line; Cell Membrane; Cyclic AMP; Glioma; Humans; Isoproterenol; Kinetics; Pindolol; Rats; Receptors, Adrenergic, beta

1984
In vitro interactions of agonists and antagonists with beta-adrenergic receptors.
    Biochemical pharmacology, 1984, Mar-15, Volume: 33, Issue:6

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Epinephrine; Guanosine Triphosphate; Humans; Isoproterenol; Magnesium; Models, Biological; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Sulfhydryl Reagents; Thermodynamics

1984
[125I]iodopindolol: a new beta adrenergic receptor probe.
    Journal of cyclic nucleotide research, 1981, Volume: 7, Issue:1

    Topics: Animals; Binding, Competitive; Dogs; Isoproterenol; Kinetics; Muscles; Myocardium; Pindolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sarcolemma

1981
An autoradiographic analysis of beta adrenergic receptors on immunocytochemically defined astroglia.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:1

    Topics: Animals; Astrocytes; Autoradiography; Cells, Cultured; Fixatives; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Histocytochemistry; Intermediate Filament Proteins; Isoproterenol; Kinetics; Pindolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1983
Evidence for intravesicular beta-adrenergic receptors in membrane fractions from desensitized cells: binding of the hydrophilic ligand CGP-12177 only in the presence of alamethicin.
    Journal of cyclic nucleotide and protein phosphorylation research, 1983, Volume: 9, Issue:2

    Topics: Alamethicin; Animals; Anti-Bacterial Agents; Cells, Cultured; Centrifugation, Density Gradient; Glioma; Isoproterenol; Pindolol; Propanolamines; Rats; Receptors, Adrenergic, beta

1983
Intact cell binding properties of cells expressing altered beta-adrenergic receptors.
    Molecular pharmacology, 1994, Volume: 45, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; beta-Adrenergic Receptor Kinases; Binding, Competitive; Cell Line; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Isoproterenol; L Cells; Metoprolol; Mice; Mutation; Phosphorylation; Pindolol; Receptors, Adrenergic, beta; Transfection

1994
Characterisation of the beta adrenergic response cascade in fetal guinea pig lung.
    Thorax, 1994, Volume: 49, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cell Membrane; Choline; Colforsin; Cyclic AMP; Gestational Age; Guinea Pigs; Isoproterenol; Lung; Models, Biological; Phosphatidylcholines; Pindolol; Radioimmunoassay; Receptors, Adrenergic, beta

1994
Ritodrine: a beta-adrenergic receptor antagonist in human amnion.
    American journal of obstetrics and gynecology, 1993, Volume: 168, Issue:1 Pt 1

    Topics: Amnion; Binding, Competitive; Cyclic AMP; Dinoprostone; Epinephrine; Humans; Isoproterenol; Norepinephrine; Pindolol; Receptors, Adrenergic, beta; Ritodrine

1993
Effect of cesarean delivery on perioperative regulation of the beta-adrenergic receptor system of human lymphocytes.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:5

    Topics: Abdomen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Alprostadil; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; Colforsin; Cyclic AMP; Down-Regulation; Female; Humans; Iodine Radioisotopes; Isoproterenol; Lymphocytes; Pindolol; Pregnancy; Receptors, Adrenergic, beta; Stress, Physiological; Thoracic Surgery; Vasodilator Agents

1996
Kinetic analysis of drug-receptor interactions of long-acting beta2 sympathomimetics in isolated receptor membranes: evidence against prolonged effects of salmeterol and formoterol on receptor-coupled adenylyl cyclase.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Binding, Competitive; Bronchodilator Agents; Cattle; Cell Membrane; Ethanolamines; Formoterol Fumarate; In Vitro Techniques; Isoproterenol; Lung; Membranes; Muscle, Smooth; Pindolol; Radioligand Assay; Rats; Receptors, Drug; Salmeterol Xinafoate; Sympathomimetics; Trachea

1999
Quasi-irreversible binding of agonist to beta-adrenoceptors and formation of non-dissociating receptor-G(s) complex in the absence of guanine nucleotides.
    European journal of pharmacology, 2001, Aug-17, Volume: 425, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Binding Sites; Binding, Competitive; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gs; Guanine Nucleotides; Guanosine Diphosphate; Guinea Pigs; Iodine Radioisotopes; Isoproterenol; Lung; Macromolecular Substances; Membranes; Pindolol; Receptors, Adrenergic, beta; Time Factors

2001