Page last updated: 2024-08-24

3-iodobenzylguanidine and topotecan

3-iodobenzylguanidine has been researched along with topotecan in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chang, YC; Flux, GD; Gaze, MN; Mairs, RJ; Meller, ST; Saran, FH1
Boyd, M; Gaze, MN; Mairs, RJ; McCluskey, AG1
Angerson, WJ; Boyd, M; Clark, AM; Cosimo, E; Gaze, MN; Mairs, RJ; McCluskey, AG; Ross, SC1
Martin, S1
Boyd, M; Mairs, RJ1
Babich, JW; Boyd, M; Gaze, MN; Mairs, RJ; McCluskey, AG; Pimlott, SL1
Babich, JW; Boyd, M; Champion, S; Gaze, MN; Mairs, RJ; McCluskey, AG; Pimlott, SL; Tesson, M1
Caron, HN; Kam, B; Kraal, KC; Tytgat, GA; van Eck-Smit, BL; van Noesel, M1
Carpentier, P; Clisant, S; Cougnenc, O; Defachelles, AS; Kolesnikov-Gauthier, H; Lervat, C; Oudoux, A1
Kraal, KC; Tytgat, GA; van Dalen, EC; Van Eck-Smit, BL1
Bogart, E; Chastagner, P; Cougnenc, O; Defachelles, AS; Ferry, I; Kolesnikov-Gauthier, H; Michon, J; Oudoux, A; Proust, S; Schleiermacher, G; Valteau-Couanet, D1
Echebarria, A; Genolla, J; Llorens, V; Lopez-Almaraz, R; Minguez, P; Rodriguez, T1
Badel, JN; Bogart, E; Corradini, N; Cougnenc, O; Courbon, F; Defachelles, AS; Deley, MCL; Gambart, M; Giraudet, AL; Kolesnikov-Gauthier, H; Oudoux, A; Rault, E; Schleiermacher, G; Sevrin, F; Valteau-Couanet, D1

Reviews

3 review(s) available for 3-iodobenzylguanidine and topotecan

ArticleYear
[131I]MIBG and topotecan: a rationale for combination therapy for neuroblastoma.
    Cancer letters, 2005, Oct-18, Volume: 228, Issue:1-2

    Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Combined Modality Therapy; DNA Damage; Enzyme Inhibitors; Humans; Neuroblastoma; Radiopharmaceuticals; Topoisomerase I Inhibitors; Topotecan

2005
Optimizing MIBG therapy of neuroendocrine tumors: preclinical evidence of dose maximization and synergy.
    Nuclear medicine and biology, 2008, Volume: 35 Suppl 1

    Topics: 3-Iodobenzylguanidine; Bystander Effect; Combined Modality Therapy; Humans; Neuroendocrine Tumors; Radiopharmaceuticals; Radiotherapy Dosage; Topotecan

2008
Iodine-131-meta-iodobenzylguanidine therapy for patients with newly diagnosed high-risk neuroblastoma.
    The Cochrane database of systematic reviews, 2017, Apr-21, Volume: 4

    Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infant; Neuroblastoma; Observational Studies as Topic; Radiopharmaceuticals; Thyroid Diseases; Topotecan

2017

Trials

4 trial(s) available for 3-iodobenzylguanidine and topotecan

ArticleYear
Upfront treatment of high-risk neuroblastoma with a combination of 131I-MIBG and topotecan.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:11

    Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Autografts; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Infant; Infant, Newborn; Male; Neuroblastoma; Prospective Studies; Risk Factors; Stem Cell Transplantation; Topotecan; Transplantation Conditioning

2015
HIGH-DOSE 131I-MIBG THERAPIES IN CHILDREN: FEASIBILITY, PATIENT DOSIMETRY AND RADIATION EXPOSURE TO WORKERS AND FAMILY CAREGIVERS.
    Radiation protection dosimetry, 2017, Apr-15, Volume: 173, Issue:4

    Topics: 3-Iodobenzylguanidine; Adult; Caregivers; Child; Female; France; Humans; Iodine Radioisotopes; Male; Neoplasm Recurrence, Local; Neuroblastoma; Radiation Exposure; Radiometry; Topoisomerase I Inhibitors; Topotecan

2017
Feasibility of Busulfan Melphalan and Stem Cell Rescue After 131I-MIBG and Topotecan Therapy for Refractory or Relapsed Metastatic Neuroblastoma: The French Experience.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6

    Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Child; Child, Preschool; Female; France; Hematopoietic Stem Cell Transplantation; Humans; Male; Melphalan; Neoplasm Metastasis; Neuroblastoma; Risk Factors; Topotecan

2018
Phase II study of
    Pediatric blood & cancer, 2023, Volume: 70, Issue:11

    Topics: 3-Iodobenzylguanidine; Adolescent; Busulfan; Child; Child, Preschool; Chronic Disease; Humans; Melphalan; Neoplasm Recurrence, Local; Neuroblastoma; Topotecan; Young Adult

2023

Other Studies

6 other study(ies) available for 3-iodobenzylguanidine and topotecan

ArticleYear
Feasibility of dosimetry-based high-dose 131I-meta-iodobenzylguanidine with topotecan as a radiosensitizer in children with metastatic neuroblastoma.
    Cancer biotherapy & radiopharmaceuticals, 2005, Volume: 20, Issue:2

    Topics: 3-Iodobenzylguanidine; Child; Child, Preschool; Dose-Response Relationship, Radiation; Female; Humans; Iodine Radioisotopes; Male; Neoplasm Metastasis; Neuroblastoma; Radiation Dosage; Radiation-Sensitizing Agents; Radiometry; Radiopharmaceuticals; Radiotherapy Dosage; Topotecan; Whole-Body Counting

2005
[131I]meta-iodobenzylguanidine and topotecan combination treatment of tumors expressing the noradrenaline transporter.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Nov-01, Volume: 11, Issue:21

    Topics: 3-Iodobenzylguanidine; Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Fragmentation; DNA, Complementary; Glioma; Humans; Iodine Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neuroblastoma; Norepinephrine Plasma Membrane Transport Proteins; Time Factors; Topotecan; Transfection

2005
New Agents in Clinical Oncology. 24 November 2006, London, UK.
    IDrugs : the investigational drugs journal, 2007, Volume: 10, Issue:2

    Topics: 3-Iodobenzylguanidine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bibenzyls; Combined Modality Therapy; Enzyme Inhibitors; Humans; Medical Oncology; Neoplasms; Norepinephrine Plasma Membrane Transport Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Proteomics; Stilbenes; Thioredoxins; Topotecan

2007
Experimental treatment of neuroblastoma using [131I]meta-iodobenzylguanidine and topotecan in combination.
    The British journal of radiology, 2008, Volume: 81 Spec No 1

    Topics: 3-Iodobenzylguanidine; Animals; Antineoplastic Combined Chemotherapy Protocols; DNA Fragmentation; Glioma; Mice; Mice, Nude; Neuroblastoma; Norepinephrine Plasma Membrane Transport Proteins; Radiopharmaceuticals; Topotecan; Treatment Outcome

2008
Inhibition of poly(ADP-Ribose) polymerase enhances the toxicity of 131I-metaiodobenzylguanidine/topotecan combination therapy to cells and xenografts that express the noradrenaline transporter.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:7

    Topics: 3-Iodobenzylguanidine; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Combined Modality Therapy; DNA Breaks; Female; Flow Cytometry; Histones; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neuroblastoma; Norepinephrine Plasma Membrane Transport Proteins; Phosphorylation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Radiopharmaceuticals; Topotecan; Tumor Stem Cell Assay

2012
Dosimetry-based high-activity therapy with
    European journal of nuclear medicine and molecular imaging, 2019, Volume: 46, Issue:7

    Topics: 3-Iodobenzylguanidine; Adolescent; Chemoradiotherapy; Child; Child, Preschool; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Male; Neoplasm Recurrence, Local; Neuroblastoma; Progression-Free Survival; Radiometry; Recurrence; Remission Induction; Retrospective Studies; Risk; Topotecan; Treatment Outcome; Young Adult

2019