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3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and ziprasidone

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with ziprasidone in 1 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(ziprasidone)
Trials
(ziprasidone)
Recent Studies (post-2010) (ziprasidone)
33040331,068254362

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)ziprasidone (IC50)
D(2) dopamine receptorHomo sapiens (human)0.005
Aspartate aminotransferase, cytoplasmicHomo sapiens (human)5.39
DRattus norvegicus (Norway rat)0.1514
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.1514
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.1514
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.1514
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.1514
Alpha-1D adrenergic receptorHomo sapiens (human)0.011
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.0004
Alpha-1A adrenergic receptorHomo sapiens (human)0.011
Alpha-1B adrenergic receptorHomo sapiens (human)0.011
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2301

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aguilar, Y; Alvarez, E; CarriĆ³, I; Catafau, AM; Corripio, I; Mena, E; Perez, V; Puigdemont, D1

Trials

1 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and ziprasidone

ArticleYear
Striatal dopaminergic D2 receptor occupancy and clinical efficacy in psychosis exacerbation: a 123I-IBZM study with ziprasidone and haloperidol.
    Progress in neuro-psychopharmacology & biological psychiatry, 2005, Volume: 29, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzamides; Drug Resistance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Neostriatum; Piperazines; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Single-Blind Method; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Failure

2005