Page last updated: 2024-09-02

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and sulpiride

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with sulpiride in 3 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(sulpiride)
Trials
(sulpiride)
Recent Studies (post-2010) (sulpiride)
33040334,152427635

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)sulpiride (IC50)
Carbonic anhydrase 1Homo sapiens (human)1.2
Carbonic anhydrase 2Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)2.019
D(2) dopamine receptorHomo sapiens (human)0.0858
D(3) dopamine receptorHomo sapiens (human)0.2651
D(2) dopamine receptorRattus norvegicus (Norway rat)0.2215
Carbonic anhydrase 4Bos taurus (cattle)0.62
D(2) dopamine receptorCanis lupus familiaris (dog)0.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG1
Angeby-Möller, K; de Paulis, T; Florvall, L; Hall, H; Johansson, L; Kumar, Y; Ogren, SO; Rämsby, S1
Boerner, R; Dresel, S; Frodl, T; Gründer, G; Hahn, K; la Fougère, C; Meisenzahl, EM; Möller, HJ; Scheuerecker, J; Schmitt, G; Schwarz, M; Stauss, J1

Trials

1 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and sulpiride

ArticleYear
Striatal D2/D3 receptor occupancy, clinical response and side effects with amisulpride: an iodine-123-iodobenzamide SPET study.
    Pharmacopsychiatry, 2008, Volume: 41, Issue:5

    Topics: Adult; Amisulpride; Antipsychotic Agents; Benzamides; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Iodine Radioisotopes; Male; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Severity of Illness Index; Statistics, Nonparametric; Sulpiride; Tomography, Emission-Computed, Single-Photon

2008

Other Studies

2 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and sulpiride

ArticleYear
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1988
Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Animals; Apomorphine; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonists; Humans; Hyperkinesis; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Salicylamides; Spiperone; Stereotyped Behavior; Structure-Activity Relationship

1985