Page last updated: 2024-09-02

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and quinpirole

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with quinpirole in 3 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(quinpirole)
Trials
(quinpirole)
Recent Studies (post-2010) (quinpirole)
33040332,2130367

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)quinpirole (IC50)
D(2) dopamine receptorRattus norvegicus (Norway rat)0.1

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billings, J; Chumpradit, S; Kung, HF; Kung, MP; Mach, R1
Brücke, T; Chiueh, CC; Cohen, RM; Kung, HF; McLellan, CA; Singhaniyom, W; Tsai, YF1
Drukarch, B; Goosen, C; Sahadat, MC; Stoof, JC; van Royen, EA; Verhoeff, NP; Vermeulen, RJ; Wolters, EC1

Other Studies

3 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and quinpirole

ArticleYear
Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Animals; Benzamides; Dopamine Agents; Dopamine D2 Receptor Antagonists; Fluorine Radioisotopes; Iodine Radioisotopes; Macaca fascicularis; Male; Pyrrolidines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1993
Blockade of in vivo binding of 125I-labeled 3-iodobenzamide (IBZM) to dopamine receptors by D2 antagonist and agonist.
    Brain research, 1988, Jun-21, Volume: 453, Issue:1-2

    Topics: Animals; Autoradiography; Benzamides; Binding, Competitive; Caudate Nucleus; Dopamine; Ergolines; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Olfactory Bulb; Pyrrolidines; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D2; Septal Nuclei

1988
No direct correlation between behaviorally active doses of the dopamine D2 agonist LY 171555 and displacement of [123I]IBZM as measured with SPECT in MPTP monkeys.
    Synapse (New York, N.Y.), 1994, Volume: 17, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcholine; Animals; Behavior, Animal; Benzamides; Binding, Competitive; Dopamine Agents; Dopamine D2 Receptor Antagonists; Ergolines; Functional Laterality; Macaca mulatta; Male; Neostriatum; Pyrrolidines; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Rotation; Stereotyped Behavior; Tomography, Emission-Computed, Single-Photon

1994