3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with haloperidol in 27 studies
| Studies (3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide) | Trials (3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide) | Recent Studies (post-2010) (3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide) | Studies (haloperidol) | Trials (haloperidol) | Recent Studies (post-2010) (haloperidol) |
|---|---|---|---|---|---|
| 330 | 40 | 33 | 20,330 | 1,753 | 3,294 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 19 (70.37) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angeby-Möller, K; de Paulis, T; Florvall, L; Hall, H; Johansson, L; Kumar, Y; Ogren, SO; Rämsby, S | 1 |
| Amici, L; Baldessarini, RJ; Baldwin, RM; Fu, X; Innis, RB; Kula, NS; Tamagnan, GD | 1 |
| Baldwin, RM; Dey, HM; Germine, M; Goddard, AW; Seibyl, JP; Smith, EO; Woods, SW; Zea-Ponce, Y; Zoghbi, SS; Zubal, G | 1 |
| al-Tikriti, M; Baldwin, RM; Hoffer, PB; Innis, RB; Laruelle, M; Malison, RT; Seibyl, JP; Smith, EO; Sybirska, EH; Zoghbi, SS | 1 |
| Bobeldijk, M; Boer, GJ; de Bruin, K; Erdtsieck-Ernste, E; Feenstra, MG; Maas, MA; van Royen, EA; Verhoeff, NP | 1 |
| Bockisch, A; Hahn, K; Hiemke, C; Nickel, O; Schlegel, S; Schlösser, R | 1 |
| Bauer, R; Dorndorf, W; Franz, M; Gallhofer, B; Jauss, M; Klett, R; Krack, P | 1 |
| Busatto, GF; Costa, DC; Ell, PJ; Kerwin, RW; Nohria, V; Pilowsky, LS; Sharma, T; Sigmundsson, T; Taylor, M | 1 |
| Hirschowitz, J; Machac, J; Vallabhajosula, S | 1 |
| Asenbaum, S; Brücke, T; Gössler, R; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J; Topitz-Schratzberger, A; Vesely, C | 1 |
| Castagnoli, N; Dormehl, IC; Hugo, N; Keeve, R; Müller-Gärtner, HW; Oliver, DW; Pond, SM; Van der Schyf, CJ | 1 |
| Hirschowitz, J; Hitzemann, R; Vallabhajosula, S | 1 |
| Castagnoli, N; Dormehl, IC; Hugo, N; Keeve, R; Müller-Gärtner, HW; Neumeyer, JL; Oliver, DW; Rossouw, NT; Van der Schyf, CJ | 1 |
| Heinz, A; Knable, MB; Raedler, T; Weinberger, DR | 1 |
| Bockisch, A; Hahn, K; Hiemke, C; Nickel, O; Rao, ML; Schlegel, S; Schlösser, R | 1 |
| Asenbaum, S; Brücke, T; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J; Vesely, C | 1 |
| Junhold, U; Künstler, U; Preiss, R; Regenthal, R | 1 |
| Asenbaum, S; Barnas, C; Brücke, T; Hesselmann, B; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J | 1 |
| Coppola, R; Gorey, JG; Heinz, A; Jones, DW; Knable, MB; Lee, KS; Weinberger, DR | 1 |
| Dähne, I; Dresel, S; Hahn, K; Mager, T; Scherer, J; Tatsch, K | 1 |
| Asenbaum, S; Barnas, C; Brücke, T; Fischer, P; Kasper, S; Küfferle, B; Pezawas, L; Tauscher, J; Tauscher-Wisniewski, S | 1 |
| Gertz, HJ; Hohdorf, K; Künstler, U; Regenthal, R; Seese, A | 1 |
| Angelo, HR; Friberg, L; Holm, S; Knudsen, GM; Toska, K; Videbaek, C | 1 |
| Bernardo, M; Catafau, AM; Font, M; Gómez, JC; Gutiérrez, F; Lomeña, F; López-Carrero, C; Parellada, E; Pavía, J; Salamero, M | 1 |
| Bédard, MA; Elie, A; Lévesque, M; Paquet, F; Soucy, JP; Stip, E | 1 |
| Aguilar, Y; Alvarez, E; Carrió, I; Catafau, AM; Corripio, I; Mena, E; Perez, V; Puigdemont, D | 1 |
| Boerner, R; Dresel, S; Frodl, T; Hahn, K; la Fougère, C; Meisenzahl, EM; Möller, HJ; Schmitt, GJ | 1 |
5 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and haloperidol
| Article | Year |
|---|---|
IBZM SPECT imaging of striatal dopamine-2 receptors in psychotic patients treated with the novel antipsychotic substance quetiapine in comparison to clozapine and haloperidol.
Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Dibenzothiazepines; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Neostriatum; Psychotic Disorders; Pyrrolidines; Quetiapine Fumarate; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1997 |
In vivo 123I IBZM SPECT imaging of striatal dopamine-2 receptor occupancy in schizophrenic patients treated with olanzapine in comparison to clozapine and haloperidol.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzamides; Benzodiazepines; Clozapine; Contrast Media; Corpus Striatum; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Olanzapine; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome | 1999 |
Double-blind olanzapine vs. haloperidol D2 dopamine receptor blockade in schizophrenic patients: a baseline-endpoint.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Benzodiazepines; Contrast Media; Corpus Striatum; Double-Blind Method; Female; Frontal Lobe; Haloperidol; Humans; Male; Olanzapine; Pirenzepine; Prospective Studies; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 2001 |
Comparison between olanzapine and haloperidol on procedural learning and the relationship with striatal D2 receptor occupancy in schizophrenia.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzamides; Benzodiazepines; Case-Control Studies; Corpus Striatum; Female; Functional Laterality; Haloperidol; Humans; Learning; Male; Olanzapine; Psychiatric Status Rating Scales; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 2004 |
Striatal dopaminergic D2 receptor occupancy and clinical efficacy in psychosis exacerbation: a 123I-IBZM study with ziprasidone and haloperidol.
Topics: Adult; Antipsychotic Agents; Benzamides; Drug Resistance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Neostriatum; Piperazines; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Single-Blind Method; Thiazoles; Tomography, Emission-Computed, Single-Photon; Treatment Failure | 2005 |
22 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and haloperidol
| Article | Year |
|---|---|
Potential neuroleptic agents. 3. Chemistry and antidopaminergic properties of substituted 6-methoxysalicylamides.
Topics: Animals; Apomorphine; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; Dopamine Antagonists; Humans; Hyperkinesis; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Salicylamides; Spiperone; Stereotyped Behavior; Structure-Activity Relationship | 1985 |
Synthesis and affinity of a possible byproduct of electrophilic radiolabeling of [123I]IBZM.
Topics: Benzamides; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Molecular Structure; Pyrrolidines; Structure-Activity Relationship | 2003 |
Dynamic SPECT imaging of dopamine D2 receptors in human subjects with iodine-123-IBZM.
Topics: Adult; Benzamides; Brain; Contrast Media; Female; Haloperidol; Humans; Male; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon | 1992 |
Amphetamine-stimulated dopamine release competes in vivo for [123I]IBZM binding to the D2 receptor in nonhuman primates.
Topics: Animals; Benzamides; Binding, Competitive; Brain; Cerebral Cortex; Corpus Striatum; Dextroamphetamine; Dopamine; Female; Haloperidol; Iodine Radioisotopes; Kinetics; Macaca mulatta; Male; Papio; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Reserpine; Tomography, Emission-Computed | 1992 |
In vitro and in vivo D2-dopamine receptor binding with [123I]S(-) iodobenzamide ([123I]IBZM) in rat and human brain.
Topics: Animals; Benzamides; Binding, Competitive; Brain; Corpus Striatum; Dopamine Antagonists; Female; Haloperidol; Humans; In Vitro Techniques; Iodine Radioisotopes; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine D2; Spiperone; Stereoisomerism | 1991 |
Prolactin plasma levels and D2-dopamine receptor occupancy measured with IBZM-SPECT.
Topics: Adult; Antipsychotic Agents; Benperidol; Benzamides; Clozapine; Corpus Striatum; Dopamine Antagonists; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Prolactin; Prosencephalon; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia, Paranoid; Tomography, Emission-Computed, Single-Photon | 1996 |
Imaging of dopamine receptors with [123I]iodobenzamide single-photon emission-computed tomography in neuroleptic malignant syndrome.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benperidol; Benzamides; Dopamine Antagonists; Frontal Lobe; Haloperidol; Humans; Iodine Radioisotopes; Male; Neuroleptic Malignant Syndrome; Neurologic Examination; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Tomography, Emission-Computed, Single-Photon | 1996 |
Dopamine D2 receptor occupancy in vivo by the novel atypical antipsychotic olanzapine--a 123I IBZM single photon emission tomography (SPET) study.
Topics: Adult; Antipsychotic Agents; Benzamides; Benzodiazepines; Corpus Striatum; Haloperidol; Humans; Middle Aged; Olanzapine; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1996 |
Effect of haloperidol dose on iodine-123-IBZM brain SPECT imaging in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Brain; Cerebellum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Pyrrolidines; Radionuclide Imaging; Receptors, Dopamine D2; Schizophrenia | 1997 |
Striatal dopamine-2 receptor occupancy in psychotic patients treated with risperidone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Brain Mapping; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon | 1996 |
Long-term treatment with the tetrahydropyridine analog (HPTP) of haloperidol influences dopamine ligand binding in baboon brain. An [123I]iodobenzamide (IBZM) SPECT study.
Topics: Animals; Benzamides; Binding, Competitive; Brain; Dopamine; Haloperidol; Male; Papio; Pyridines; Pyrrolidines; Time Factors; Tomography, Emission-Computed, Single-Photon | 1996 |
SPECT studies of D2 occupancy in low-dose haloperidol treatment.
Topics: Adult; Basal Ganglia; Benzamides; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon | 1997 |
Effect of the haloperidol tetrahydropyridine metabolite 4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]-1,2,3,6- tetrahydropyridine on dopamine receptor and transporter binding. A nonhuman primate 123I-iodobenzamide and 2 beta-carbomethoxy-3 beta-(4-
Topics: Animals; Antipsychotic Agents; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Haloperidol; Iodine Radioisotopes; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Pyrrolidines; Receptors, Dopamine; Tomography, Emission-Computed, Single-Photon | 1997 |
Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levels.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Brain; Brain Mapping; Dopamine Antagonists; Drug Therapy, Combination; Female; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Parkinson Disease, Secondary; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Tomography, Emission-Computed, Single-Photon | 1997 |
[123I]IBZM SPECT in patients treated with typical and atypical neuroleptics: relationship to drug plasma levels and extrapyramidal side effects.
Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia Diseases; Benperidol; Benzamides; Bipolar Disorder; Brain; Clozapine; Corpus Striatum; Depressive Disorder, Major; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Frontal Lobe; Haloperidol; Humans; Male; Middle Aged; Neurologic Examination; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia, Paranoid; Tomography, Emission-Computed, Single-Photon | 1997 |
Haloperidol serum concentrations and D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate.
Topics: Adult; Aged; Antipsychotic Agents; Benzamides; Brain; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1997 |
Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study.
Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1998 |
Psychomotor slowing, negative symptoms and dopamine receptor availability--an IBZM SPECT study in neuroleptic-treated and drug-free schizophrenic patients.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzamides; Brain; Dopamine Antagonists; Haloperidol; Humans; Middle Aged; Psychomotor Disorders; Pyrrolidines; Reaction Time; Receptors, Dopamine; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1998 |
Iodine-123-iodobenzamide SPECT assessment of dopamine D2 receptor occupancy in riperidone-treated schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Brain; Clozapine; Contrast Media; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon | 1998 |
[Diminution of hand writing area and D2-dopamine receptor blockade. Results from treatment with typical and atypical neuroleptics].
Topics: Adult; Aged; Antipsychotic Agents; Benzamides; Clozapine; Dopamine Antagonists; Female; Haloperidol; Handwriting; Humans; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine; Risperidone; Schizophrenia, Paranoid; Therapeutic Equivalency; Tomography, Emission-Computed, Single-Photon | 2000 |
In vivo measurement of haloperidol affinity to dopamine D2/D3 receptors by [123I]IBZM and single photon emission computed tomography.
Topics: Adult; Animals; Autoradiography; Benzamides; Brain; Cerebrovascular Circulation; Female; Haloperidol; Humans; Infusions, Intravenous; Iodine Radioisotopes; Kinetics; Male; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tomography, Emission-Computed, Single-Photon | 2001 |
Dual-isotope SPECT imaging of striatal dopamine: a comparative study between never-treated and haloperidol-treated first-episode schizophrenic patients.
Topics: Adolescent; Adult; Analysis of Variance; Benzamides; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Haloperidol; Humans; Male; Organotechnetium Compounds; Protein Binding; Psychiatric Status Rating Scales; Pyrrolidines; Radiopharmaceuticals; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes; Young Adult | 2012 |