Page last updated: 2024-09-02

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and domperidone

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with domperidone in 2 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(domperidone)
Trials
(domperidone)
Recent Studies (post-2010) (domperidone)
33040331,977275468

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)domperidone (IC50)
Solute carrier family 22 member 2Homo sapiens (human)7.9
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.332
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.614
Alpha-2A adrenergic receptorHomo sapiens (human)2.74
D(2) dopamine receptorHomo sapiens (human)0.0026
Alpha-2B adrenergic receptorHomo sapiens (human)2.125
Alpha-2C adrenergic receptorHomo sapiens (human)1.011
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.614
Alpha-1D adrenergic receptorHomo sapiens (human)1.065
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.037
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.332
Sodium-dependent serotonin transporterHomo sapiens (human)3.055
Histamine H1 receptorHomo sapiens (human)1.344
Mu-type opioid receptorHomo sapiens (human)4.218
D(3) dopamine receptorHomo sapiens (human)0.018
Kappa-type opioid receptorHomo sapiens (human)6.994
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.6
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0052
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1447
Multidrug and toxin extrusion protein 1Homo sapiens (human)2.3

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Healy, DP; Huo, TL1
Bush, M; Ehrenkaufer, RE; Kung, HF; Luedtke, RR; Mach, RH; Molinoff, PB1

Other Studies

2 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and domperidone

ArticleYear
Prostaglandin E2 production in rat IMCD cells. I. Stimulation by dopamine.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2

    Topics: Animals; Benzamides; Cells, Cultured; Dinoprostone; Domperidone; Dopamine; Dopamine Antagonists; Hydrazines; Kidney Medulla; Kidney Tubules, Collecting; Male; Pertussis Toxin; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine D2; Virulence Factors, Bordetella

1991
Antibodies with high affinity for spiroperidol--II. Cross reactivity with iodobenzamide and domperidone.
    Molecular immunology, 1990, Volume: 27, Issue:7

    Topics: Animals; Antibodies, Heterophile; Antibody Affinity; Antibody Specificity; Benzamides; Binding, Competitive; Cross Reactions; Domperidone; Haptens; Hybridomas; Mice; Pyrrolidines; Rabbits; Spiperone

1990