Page last updated: 2024-09-02

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and butaclamol

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with butaclamol in 3 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(butaclamol)
Trials
(butaclamol)
Recent Studies (post-2010) (butaclamol)
33040333308

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)butaclamol (IC50)
D(2) dopamine receptorHomo sapiens (human)0.0123
DRattus norvegicus (Norway rat)0.002
D(3) dopamine receptorRattus norvegicus (Norway rat)0.002
D(1A) dopamine receptorHomo sapiens (human)0.05
D(4) dopamine receptorHomo sapiens (human)0.05
D(1B) dopamine receptorHomo sapiens (human)0.05
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.002
D(4) dopamine receptorRattus norvegicus (Norway rat)0.002
D(3) dopamine receptorHomo sapiens (human)0.0139
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0053
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.0525

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Billings, J; Kung, HF; Kung, MP; Murphy, RA1
Guo, YZ; Kasliwal, R; Kung, HF; Kung, MP; Mach, RH; Pan, SG1
Billings, J; Chumpradit, S; Kung, HF; Kung, MP; Mach, R1

Other Studies

3 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and butaclamol

ArticleYear
Synthesis and characterization of iodobenzamide analogues: potential D-2 dopamine receptor imaging agents.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Benzofurans; Binding, Competitive; Chemical Phenomena; Chemistry; Corpus Striatum; Iodine Radioisotopes; Isotope Labeling; Male; Molecular Structure; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Tissue Distribution

1990
Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:5

    Topics: Animals; Benzamides; Chemical Phenomena; Chemistry; Corpus Striatum; In Vitro Techniques; Iodine Radioisotopes; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship

1988
Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT.
    Journal of medicinal chemistry, 1993, Jan-22, Volume: 36, Issue:2

    Topics: Animals; Benzamides; Dopamine Agents; Dopamine D2 Receptor Antagonists; Fluorine Radioisotopes; Iodine Radioisotopes; Macaca fascicularis; Male; Pyrrolidines; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

1993