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3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and bromocriptine

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with bromocriptine in 4 studies

Compound Research Comparison

Studies
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Trials
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Recent Studies (post-2010)
(3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide)
Studies
(bromocriptine)
Trials
(bromocriptine)
Recent Studies (post-2010) (bromocriptine)
33040337,121727499

Protein Interaction Comparison

ProteinTaxonomy3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide (IC50)bromocriptine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.532
Beta-1 adrenergic receptorHomo sapiens (human)2.4
Cytochrome P450 3A4Homo sapiens (human)2.4996
Alpha-2A adrenergic receptorHomo sapiens (human)0.015
D(2) dopamine receptorHomo sapiens (human)0.0016
Androgen receptorRattus norvegicus (Norway rat)2.281
Alpha-2B adrenergic receptorHomo sapiens (human)0.035
Alpha-2C adrenergic receptorHomo sapiens (human)0.52
DRattus norvegicus (Norway rat)0.0279
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0279
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0056
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.514
D(1A) dopamine receptorHomo sapiens (human)2.889
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.514
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.514
Alpha-1D adrenergic receptorHomo sapiens (human)0.03
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0279
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.036
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.532
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0056
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0279
D(3) dopamine receptorHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0083
5-hydroxytryptamine receptor 6Homo sapiens (human)0.022
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0279

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D'Angelo, V; Di Fazio, P; Dicembrino, F; Liuzzi, A; Scarabino, T; Scillitani, A; Vettori, PP1
Emrich, D; Hajak, G; Kögler, A; Munz, DL; Riemann, H; Rüther, E; Staedt, J; Stoppe, G1
Hartman, NG; Lavigne, GJ; Lobbezoo, F; Montplaisir, JY; Soucy, JP1
Ambrosio, G; Battista, C; Cascini, GL; Mansi, L; Panza, N; Rambaldi, PF; Schillirò, F1

Trials

2 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and bromocriptine

ArticleYear
Single photon emission tomography (SPET) imaging of dopamine D2 receptors in the course of dopamine replacement therapy in patients with nocturnal myoclonus syndrome (NMS).
    Journal of neural transmission. General section, 1995, Volume: 99, Issue:1-3

    Topics: Aged; Benzamides; Brain; Brain Chemistry; Bromocriptine; Dopamine; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Female; Humans; Iodine Radioisotopes; Levodopa; Male; Middle Aged; Myoclonus; Polysomnography; Pyrrolidines; Receptors, Dopamine D2; Sleep Wake Disorders; Tomography, Emission-Computed, Single-Photon

1995
Effects of the D2 receptor agonist bromocriptine on sleep bruxism: report of two single-patient clinical trials.
    Journal of dental research, 1997, Volume: 76, Issue:9

    Topics: Adult; Benzamides; Bromocriptine; Bruxism; Corpus Striatum; Cross-Over Studies; Dizziness; Dopamine Agonists; Dopamine Antagonists; Double-Blind Method; Electromyography; Female; Humans; Iodine Radioisotopes; Male; Masseter Muscle; Nausea; Patient Dropouts; Placebos; Polysomnography; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine; Sleep; Tomography, Emission-Computed, Single-Photon; Treatment Outcome

1997

Other Studies

2 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and bromocriptine

ArticleYear
In vivo visualization of pituitary dopaminergic receptors by iodine-123 methoxybenzamide (IBZM) correlates with sensitivity to dopamine agonists in two patients with macroprolactinomas.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:8

    Topics: Adult; Benzamides; Brain; Bromocriptine; Female; Humans; Iodine Radioisotopes; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Pituitary Gland; Pituitary Neoplasms; Prolactin; Prolactinoma; Pyrrolidines; Receptors, Dopamine; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon

1995
Receptor imaging with 111In-pentreotide and 123I-methoxybenzamide, and inhibition tests with octreotide and bromocriptine of mixed growth hormone/prolactin-secreting pituitary tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1999, Volume: 53, Issue:7

    Topics: Adult; Benzamides; Bromocriptine; Contrast Media; Growth Hormone; Humans; Indium Radioisotopes; Iodine Radioisotopes; Magnetic Resonance Imaging; Male; Middle Aged; Octreotide; Pituitary Neoplasms; Prolactin; Pyrrolidines; Radionuclide Imaging; Tomography

1999