3-hydroxyquinolin-2(1h)-one has been researched along with sulfuric-acid* in 1 studies
1 other study(ies) available for 3-hydroxyquinolin-2(1h)-one and sulfuric-acid
Article | Year |
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One-pot synthesis of 3-hydroxyquinolin-2(1H)-ones from N-phenylacetoacetamide via PhI(OCOCF3)2-mediated α-hydroxylation and H2SO4-promoted intramolecular cyclization.
A clean, one-pot synthesis of the biologically important 3-hydroxyquinolin-2(1H)-one compounds has been realized from the readily available N-phenylacetoacetamide derivatives through a PhI(OCOCF3)2-mediated α-hydroxylation and a H2SO4-promoted intramolecular condensation. The hydroxyl group in the generated α-hydroxylated intermediate can be well tolerated in the second H2SO4-promoted cyclization step. Topics: Acetanilides; Cyclization; Hydroxylation; Iodobenzenes; Molecular Structure; Quinolones; Sulfuric Acids; Trifluoroacetic Acid | 2013 |