Compounds > 3-hydroxyquinidine

3-hydroxyquinidine and fluvoxamine

3-hydroxyquinidine has been researched along with fluvoxamine in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brøsen, K; Damkier, P; Hansen, LL1
Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA; Westerberg, PA1
Bertilsson, L; Ericsson, O; Gustafsson, LL; Mirghani, RA; Tybring, G1
Bertilsson, L; Ericsson, O; Gustafsson, LL; Hellgren, U; Mirghani, RA1

Trials

4 trial(s) available for 3-hydroxyquinidine and fluvoxamine

ArticleYear
Effect of fluvoxamine on the pharmacokinetics of quinidine.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:6

    Topics: Anti-Arrhythmia Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Fluvoxamine; Humans; Male; Metabolic Clearance Rate; Quinidine; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1999
The roles of cytochrome P450 3A4 and 1A2 in the 3-hydroxylation of quinine in vivo.
    Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:5

    Topics: Adult; Antifungal Agents; Antimalarials; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Fluvoxamine; Humans; Hydroxylation; Ketoconazole; Male; Mixed Function Oxygenases; Quinidine; Quinine; Selective Serotonin Reuptake Inhibitors

1999
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man.
    European journal of clinical pharmacology, 2003, Volume: 59, Issue:1

    Topics: Adult; Biomarkers; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Fluvoxamine; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Male; Middle Aged; Quinidine; Quinine

2003
Metabolism and elimination of quinine in healthy volunteers.
    European journal of clinical pharmacology, 2003, Volume: 59, Issue:5-6

    Topics: Antimalarials; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Benzoquinones; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Mixed Function Oxygenases; Quinidine; Quinine; Quinones; Time Factors

2003