3-hydroxypregn-4-en-20-one has been researched along with 20-alpha-dihydroprogesterone in 28 studies
| Studies (3-hydroxypregn-4-en-20-one) | Trials (3-hydroxypregn-4-en-20-one) | Recent Studies (post-2010) (3-hydroxypregn-4-en-20-one) | Studies (20-alpha-dihydroprogesterone) | Trials (20-alpha-dihydroprogesterone) | Recent Studies (post-2010) (20-alpha-dihydroprogesterone) |
|---|---|---|---|---|---|
| 29 | 0 | 2 | 534 | 4 | 26 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (21.43) | 18.7374 |
| 1990's | 15 (53.57) | 18.2507 |
| 2000's | 4 (14.29) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, LL; Harris, RA; Lin, LH; Zirrolli, JA | 1 |
| Morrow, AL; Pace, JR; Paul, SM; Purdy, RH | 1 |
| Barr, KJ; Buckingham, KD; Wiebe, JP | 1 |
| Tuckey, RC | 1 |
| Wiebe, JP; Wood, PH | 2 |
| Campbell, SM; Wiebe, JP | 1 |
| Asem, EK; Li, M; Mattice, DF; Tsang, BK | 1 |
| Gorospe, WC; Kasson, BG; Tuchel, T | 1 |
| Kavaliers, M; Wiebe, JP | 1 |
| Bolger, MB; Gee, KW; Hawkinson, JE; Kimbrough, CL; Lan, NC; McCauley, LD | 1 |
| Galea, LA; Kavaliers, M; Wiebe, JP | 2 |
| Dallaire, MJ; De Gannes, GC; Wiebe, JP | 1 |
| Dhanvantari, S; Wiebe, JP | 1 |
| Dhanvantari, S; Huang, Y; Watson, PH; Wiebe, JP | 1 |
| Albrecht, ED; Pepe, GJ; Waddell, BJ | 1 |
| Wiebe, JP | 1 |
| Boushy, D; Wiebe, JP; Wolfe, M | 1 |
| Beck, CA; Murphy, LD; Wiebe, JP; Wolfe, M | 1 |
| Kavaliers, M; Ossenkopp, KP; Wiebe, JP | 1 |
| Weiler, PJ; Wiebe, JP | 1 |
| Griffin, LD; Mellon, SH | 1 |
| Pawlak, KJ; Wiebe, JP; Zhang, G | 1 |
| Covey, DF; Izumi, Y; Krishnan, K; Murayama, K; Tokuda, K; Zorumski, CF | 1 |
| Beausoleil, M; Cialacu, V; Wiebe, JP; Zhang, G | 1 |
| Cadieux-Pitre, HA; Welch, I; Wiebe, JP; Zhang, G | 1 |
| Götte, M; Kiesel, L; Sourouni, M; von Wahlde, MK | 1 |
1 review(s) available for 3-hydroxypregn-4-en-20-one and 20-alpha-dihydroprogesterone
| Article | Year |
|---|---|
Nongenomic actions of steroids on gonadotropin release.
Topics: 20-alpha-Dihydroprogesterone; Animals; Estradiol; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Gonads; Humans; Male; Progesterone; Steroids; Testosterone | 1997 |
27 other study(ies) available for 3-hydroxypregn-4-en-20-one and 20-alpha-dihydroprogesterone
| Article | Year |
|---|---|
General anesthetics potentiate gamma-aminobutyric acid actions on gamma-aminobutyric acidA receptors expressed by Xenopus oocytes: lack of involvement of intracellular calcium.
Topics: 20-alpha-Dihydroprogesterone; Anesthetics; Animals; Binding Sites; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Enflurane; Female; gamma-Aminobutyric Acid; Halothane; Male; Mice; Mice, Inbred BALB C; Oocytes; Receptors, GABA-A; Xenopus | 1992 |
Characterization of steroid interactions with gamma-aminobutyric acid receptor-gated chloride ion channels: evidence for multiple steroid recognition sites.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cerebral Cortex; Chloride Channels; Chlorides; Desoxycorticosterone; In Vitro Techniques; Ion Channel Gating; Ion Channels; Membrane Proteins; Pregnanolone; Rats; Receptors, GABA-A; Steroids; Structure-Activity Relationship; Synaptosomes | 1990 |
A radioimmunoassay for the regulatory allylic steroid, 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP).
Topics: 20-alpha-Dihydroprogesterone; Animals; Antibody Specificity; Cells, Cultured; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Female; Gas Chromatography-Mass Spectrometry; Male; Ovariectomy; Progesterone; Rabbits; Radioimmunoassay; Rats; Rats, Inbred Strains; Reproducibility of Results; Sensitivity and Specificity; Sertoli Cells | 1991 |
Side-chain cleavage of cholesterol sulfate by ovarian mitochondria.
Topics: 20-alpha-Dihydroprogesterone; Aminoglutethimide; Animals; Binding, Competitive; Cholesterol Esters; Cytochrome P-450 Enzyme System; Female; Hydrolysis; Kinetics; Mitochondria; Ovary; Rats; Rats, Inbred Strains; Substrate Specificity; Swine | 1990 |
Selective suppression of follicle-stimulating hormone secretion in anterior pituitary cells by the gonadal steroid 3 alpha-hydroxy-4-pregnen-20-one.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cells, Cultured; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Gonadotropins; Isomerism; Male; Pituitary Gland, Anterior; Progesterone; Rats; Rats, Inbred Strains | 1989 |
Stimulation of spermatocyte development in prepubertal rats by the Sertoli cell steroid, 3 alpha-hydroxy-4-pregnen-20-one.
Topics: 20-alpha-Dihydroprogesterone; Animals; Animals, Newborn; Estradiol; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Organ Size; Progesterone; Prostate; Rats; Rats, Inbred Strains; Seminal Vesicles; Seminiferous Tubules; Sperm Count; Spermatocytes; Spermatogenesis; Testis; Testosterone | 1989 |
Influence of A23187 and dibutyryl cyclic AMP on progestagen production by rat granulosa cells in vitro.
Topics: 20-alpha-Dihydroprogesterone; Animals; Bucladesine; Calcimycin; Cells, Cultured; Female; Follicle Stimulating Hormone; Granulosa Cells; Pregnenolone; Progesterone; Rats | 1989 |
Selective suppression of follicle-stimulating hormone by 3 alpha-hydroxy-4-pregnen-20-one, a steroid found in Sertoli cells.
Topics: 20-alpha-Dihydroprogesterone; Age Factors; Cells, Cultured; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Orchiectomy; Ovariectomy; Pituitary Gland, Anterior; Progesterone; Secretory Rate; Sertoli Cells; Structure-Activity Relationship | 1987 |
Gamma-interferon inhibits rat granulosa cell differentiation in culture.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cell Differentiation; Cells, Cultured; Estrogens; Female; Follicle Stimulating Hormone; Granulosa Cells; Interferon Type I; Interferon-gamma; Progesterone; Rats; Receptors, LH | 1988 |
Analgesic effects of the putative FSH-suppressing gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one: possible modes of action.
Topics: 20-alpha-Dihydroprogesterone; Analgesia; Analgesics; Animals; Bicuculline; Calcium Channel Blockers; Cerebral Ventricles; Flumazenil; Follicle Stimulating Hormone; Injections, Intraventricular; Male; Mice; Naloxone; Progesterone; Reference Values | 1988 |
The neuroactive steroid 3 alpha-hydroxy-5 beta-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor.
Topics: 20-alpha-Dihydroprogesterone; Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebellum; Convulsants; Flunitrazepam; Hippocampus; In Vitro Techniques; Ligands; Male; Membranes; Receptors, GABA-A; Thalamus | 1994 |
Reduction of predator odor-induced anxiety in mice by the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP).
Topics: 20-alpha-Dihydroprogesterone; Animals; Anti-Anxiety Agents; Anxiety; Cats; Injections, Intraventricular; Male; Mice; Odorants; Predatory Behavior | 1994 |
Male preference for the odors of estrous female mice is enhanced by the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP).
Topics: 20-alpha-Dihydroprogesterone; Animals; Dose-Response Relationship, Drug; Estrus; Female; GABA Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Odorants; Sexual Behavior, Animal; Stereoisomerism | 1994 |
Synthesis of the allylic regulatory steroid, 3 alpha-hydroxy-4-pregnen-20-one, by rat granulosa cells and its regulation by gonadotropins.
Topics: 20-alpha-Dihydroprogesterone; Animals; Cells, Cultured; Diestrus; Estrus; Female; Follicle Stimulating Hormone; Gas Chromatography-Mass Spectrometry; Granulosa Cells; Hypophysectomy; Luteinizing Hormone; Ovariectomy; Proestrus; Progesterone; Rats; Rats, Sprague-Dawley | 1994 |
Suppression of follicle-stimulating hormone by the gonadal- and neurosteroid 3 alpha-hydroxy-4-pregnen-20-one involves actions at the level of the gonadotrope membrane/calcium channel.
Topics: 20-alpha-Dihydroprogesterone; Animals; Calcimycin; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine | 1994 |
Suppression in gonadotropes of gonadotropin-releasing hormone-stimulated follicle-stimulating hormone release by the gonadal- and neurosteroid 3 alpha-hydroxy-4-pregnen-20-one involves cytosolic calcium.
Topics: 20-alpha-Dihydroprogesterone; Animals; Biological Transport; Calcium; Cytosol; Enzyme Activation; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Sprague-Dawley | 1994 |
Progesterone and 20 alpha-hydroxypregn-4-en-3-one (20 alpha-OHP) in the pregnant baboon: selective placental secretion of 20 alpha-OHP into the fetal compartment.
Topics: 20-alpha-Dihydroprogesterone; Animals; Female; Gestational Age; Male; Papio; Placenta; Pregnancy; Progesterone; Radioimmunoassay; Umbilical Arteries; Umbilical Veins | 1996 |
Synthesis, metabolism and levels of the neuroactive steroid, 3alpha-hydroxy-4-pregnen-20-one (3alphaHP), in rat pituitaries.
Topics: 20-alpha-Dihydroprogesterone; Animals; Autoradiography; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Gas Chromatography-Mass Spectrometry; Pituitary Gland; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1997 |
Acute, nongenomic actions of the neuroactive gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP), on FSH release in perifused rat anterior pituitary cells.
Topics: 20-alpha-Dihydroprogesterone; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Agonists; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; GABA Modulators; Gonadotropin-Releasing Hormone; Ionophores; Perfusion; Pituitary Gland, Anterior; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 1997 |
Brief exposure of mice to 60 Hz magnetic fields reduces the analgesic effects of the neuroactive steroid, 3alpha-hydroxy-4-pregnen-20-one.
Topics: 20-alpha-Dihydroprogesterone; Analgesics; Animals; Cerebral Cortex; Electromagnetic Fields; Injections, Intraventricular; Male; Mice; Neurons | 1998 |
Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Binding Sites; Breast Neoplasms; Cell Fractionation; Cell Membrane; Cell Nucleus; Cytosol; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Pregnanediones; Progesterone; Receptors, Cell Surface; Substrate Specificity; Thermodynamics; Tumor Cells, Cultured | 2000 |
Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release.
Topics: 20-alpha-Dihydroprogesterone; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Animals; Cholestenone 5 alpha-Reductase; Enzymes; Female; Fluoxetine; Follicle Stimulating Hormone; Humans; Oxidoreductases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Tissue Distribution | 2001 |
Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone, with
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Antineoplastic Agents; Breast Neoplasms; Cell Adhesion; Cell Fractionation; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cycloheximide; Dactinomycin; Down-Regulation; Estradiol; Female; Humans; Progesterone; Receptors, Estradiol; Receptors, Progesterone; Up-Regulation | 2005 |
GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices.
Topics: 2-Amino-5-phosphonovalerate; 20-alpha-Dihydroprogesterone; Animals; Animals, Newborn; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Picrotoxin; Rats; Rats, Sprague-Dawley | 2007 |
Opposing actions of the progesterone metabolites, 5alpha-dihydroprogesterone (5alphaP) and 3alpha-dihydroprogesterone (3alphaHP) on mitosis, apoptosis, and expression of Bcl-2, Bax and p21 in human breast cell lines.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Glands, Human; Mitosis; Progesterone; Proto-Oncogene Proteins c-bcl-2 | 2010 |
Progesterone metabolites regulate induction, growth, and suppression of estrogen- and progesterone receptor-negative human breast cell tumors.
Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice, Inbred NOD; Mice, SCID; Receptors, Estrogen; Receptors, Progesterone; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Effect of 3α-dihydroprogesterone and 5α-dihydroprogesterone on DCIS cells and possible impact for postmenopausal women.
Topics: 20-alpha-Dihydroprogesterone; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Tumor; Female; Humans; Postmenopause; Progesterone | 2023 |