3-hydroxyphencyclidine has been researched along with phencyclidine in 11 studies
| Studies (3-hydroxyphencyclidine) | Trials (3-hydroxyphencyclidine) | Recent Studies (post-2010) (3-hydroxyphencyclidine) | Studies (phencyclidine) | Trials (phencyclidine) | Recent Studies (post-2010) (phencyclidine) |
|---|---|---|---|---|---|
| 12 | 0 | 2 | 28,294 | 387 | 7,796 |
| Protein | Taxonomy | 3-hydroxyphencyclidine (IC50) | phencyclidine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1299 | |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | 0.091 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.5563 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.205 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 1.2589 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1299 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1299 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.53 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1299 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Chiche, B; Geneste, P; Goudal, R; Kamenka, JM; Lazdunski, M; Vignon, J; Vincent, JP | 1 |
| Itzhak, Y | 3 |
| Itzhak, Y; Khouri, M | 1 |
| Itzhak, Y; Johnson, N; Pasternak, GW | 1 |
| Itzhak, Y; Kalir, A; Sarne, Y | 1 |
| Abe, S; Ho, IK; Hori, T; Ito, T; Moroji, T; Shiraishi, H; Suzuki, T; Yamamoto, T | 1 |
| Baba, A; Ho, IK; Hori, T; Ito, T; Piletz, JE; Shiraishi, H; Suzuki, T; Yamamoto, T | 1 |
| Archer, J; Dargan, P; Dunlop, LC; Hudson, S; Wood, D | 1 |
| Ameline, A; Baudry, M; Garnier, D; Kintz, P; Raul, JS | 1 |
11 other study(ies) available for 3-hydroxyphencyclidine and phencyclidine
| Article | Year |
|---|---|
Chemical synthesis and molecular pharmacology of hydroxylated 1-(1-phenylcyclohexyl-piperidine derivatives.
Topics: Animals; Binding, Competitive; Biotransformation; Chemical Phenomena; Chemistry; Hydroxylation; In Vitro Techniques; Kinetics; Mice; Molecular Conformation; Phencyclidine; Rats; Receptors, Muscarinic; Receptors, Opioid; Stereoisomerism | 1982 |
High and low affinity psychotomimetic opioid binding sites: characterization by a novel 3H-PCP-analog.
Topics: Animals; Brain; Cell Membrane; Guinea Pigs; Kinetics; Phencyclidine; Receptors, Opioid | 1986 |
Regulation of the binding of sigma- and phencyclidine (PCP)-receptor ligands in rat brain membranes by guanine nucleotides and ions.
Topics: Animals; Binding, Competitive; Brain; Cations; Guanine Nucleotides; Male; Phenazocine; Phencyclidine; Piperidines; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine; Subcellular Fractions | 1988 |
Pharmacological specificity of some psychotomimetic and antipsychotic agents for the sigma and PCP binding sites.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Haloperidol; In Vitro Techniques; Male; Phenazocine; Phencyclidine; Piperidines; Psychotropic Drugs; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1988 |
[3H]PCP-3-OH and (+)[3H]SKF 10047 binding sites in rat brain membranes: evidence of multiplicity.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Haloperidol; In Vitro Techniques; Phenazocine; Phencyclidine; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1987 |
Interaction of two phencyclidine opiate-like derivatives with 3H-opioid binding sites.
Topics: Analgesics; Animals; Binding, Competitive; Dihydromorphine; Male; Naloxone; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1984 |
On the opioid nature of phencyclidine and its 3-hydroxy derivative.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Mice; Phencyclidine; Radioligand Assay; Receptors, Opioid; Vas Deferens | 1981 |
Quantitative autoradiographic localization of [3H]3-OH-PCP (1-(1(3-hydroxyphenyl)cyclohexyl)piperidine) binding sites in rat brain.
Topics: Analgesics, Opioid; Animals; Autoradiography; Brain; Dizocilpine Maleate; Image Processing, Computer-Assisted; Kinetics; Ligands; Male; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine | 1995 |
Autoradiographic study on the pharmacological characteristics of [3H]3-OH-PCP binding sites in rat brain.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Kinetics; Male; Phencyclidine; Rats; Rats, Wistar; Tritium | 1996 |
Severe Toxicity to the New Psychoactive Substances 3-Hydroxyphencyclidine and N-Ethylhexedrone: an Analytically Confirmed Case Report.
Topics: Humans; Male; Middle Aged; Phencyclidine; Poisoning; Predictive Value of Tests; Psychotropic Drugs; Severity of Illness Index; Substance Abuse Detection; Substance-Related Disorders; Urinalysis | 2020 |
Case report of a fatal 3-hydroxyphencyclidine intoxication, including blood and hair results.
Topics: Adult; Hair; Humans; Male; Phencyclidine; Powders; Substance-Related Disorders | 2023 |