Page last updated: 2024-08-21

3-hydroxyflavone and 6-hydroxyflavone

3-hydroxyflavone has been researched along with 6-hydroxyflavone in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's3 (23.08)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A1
Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Holman, TR; Kenyon, V; Ohri, RV; Sepúlveda-Boza, S; Vasquez-Martinez, Y1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Amić, D; Lucić, B1
Binnie, M; Estrada-Soto, S; Medina-Franco, JL; Navarrete-Vázquez, G; Ortiz-Andrade, R; Singh, N; Torres-Piedra, M; Villalobos-Molina, R; Webster, SP1
Ataide Martins, JP; Borges de Melo, E; Castro Ferreira, MM; Friozi, MC; Marinho Jorge, TC1
Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K1
Estrada-Soto, S; Figueroa, M; Hernández-Abreu, O; Ibarra-Barajas, M; Navarrete-Vázquez, G; Torres-Piedra, M1
Abramić, M; Agić, D; Bešlo, D; Brkić, H; Karačić, Z; Lisjak, M; Špoljarević, M; Tomić, S1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Wang, H; Wang, Y; Xiao, J; Yang, F; Yuan, Y; Zhao, Y1

Other Studies

13 other study(ies) available for 3-hydroxyflavone and 6-hydroxyflavone

ArticleYear
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
    Journal of natural products, 1995, Volume: 58, Issue:2

    Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavonoids; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Stomach Diseases; Structure-Activity Relationship

1995
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.
    Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23

    Topics: Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Drug Evaluation, Preclinical; Epithelial Cells; Flavonoids; Humans; Inhibitory Concentration 50; Isoenzymes; Lipoxygenase Inhibitors; Male; Models, Molecular; Molecular Structure; Prostate; Reticulocytes; Stereoisomerism; Structure-Activity Relationship

2007
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Computational Biology; Databases, Factual; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Lipids; Models, Molecular; Molecular Conformation; Niacinamide; Quercetin; Rats; Software

2010
Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Algorithms; Antimutagenic Agents; Flavonoids; Fluorenes; Least-Squares Analysis; Models, Biological; Models, Molecular; Mutagens; Quantitative Structure-Activity Relationship; Salmonella typhimurium

2010
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2010
Vasorelaxant effect of flavonoids through calmodulin inhibition: Ex vivo, in vitro, and in silico approaches.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Aorta; Calmodulin; Dose-Response Relationship, Drug; Flavonoids; In Vitro Techniques; Models, Molecular; Rats; Rats, Wistar; Vasodilator Agents

2011
Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach.
    Chemical biology & drug design, 2017, Volume: 89, Issue:4

    Topics: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Flavonoids; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Principal Component Analysis; Protease Inhibitors; Quantitative Structure-Activity Relationship

2017
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Influences of glucose on the dietary hydroxyflavonoid-plasma protein interaction.
    Journal of agricultural and food chemistry, 2012, Dec-12, Volume: 60, Issue:49

    Topics: Adult; Apigenin; Binding Sites; Binding, Competitive; Blood Glucose; Blood Proteins; Diet; Dietary Supplements; Flavonoids; Glucose; Humans; Hydrogen Bonding; Kaempferols; Luteolin

2012