Compounds > 3-hydroxybutyric acid

3-hydroxybutyric acid and pentylenetetrazole

3-hydroxybutyric acid has been researched along with pentylenetetrazole in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (18.75)	18.2507
2000's	8 (50.00)	29.6817
2010's	4 (25.00)	24.3611
2020's	1 (6.25)	2.80

Authors

Authors	Studies
Bough, KJ; Eagles, DA	2
Bough, KJ; Eagles, DA; Han, FT; Valiyil, R	1
Bough, KJ; Chen, RS; Eagles, DA	1
Bough, KJ; Eagles, DA; Yao, SG	1
Bough, KJ; Eagles, DA; Matthews, PJ	1
Burnham, WM; Cunnane, SC; Dell, C; Iracleous, C; Likhodii, SS; Mendonca, A; Musa, K; Thavendiranathan, P	1
Allan, F; Boyd, SJ; Eagles, DA; Kotak, A	1
Abdelmalik, PA; Burnham, WM; Clarke, J; Likhodii, S; Nylen, K	1
Ferrandon, A; François, J; Koning, E; Nehlig, A; Raffo, E	1
Auvin, S; Bordet, R; Bouchaert, E; Lecointe, C; Porta, N; Staels, B; Vallée, L	1
Bergbower, E; Hardwick, JM; Hartman, AL; Kennedy, M; Zheng, X	1
French, A; Gasior, M; Hartman, AL; Rogawski, MA; Yankura, J	1
Dolce, A; Hardwick, JM; Hartman, AL; Santos, P	1
Coppola, G; Iovane, V; Monda, M; Operto, FF; Pisano, S; Stoddard, M; Viggiano, A	1
Astori, S; Carleton, A; De La Rossa, A; Duchen, MR; Khani, A; Laporte, MH; Marissal, T; Martinou, JC; Mendez, P; Montessuit, S; Nunes, JM; Quairiaux, C; Ramos-Fernández, E; Rutter, J; Sandi, C; Sheshadri, P; Taylor, EB	1

Other Studies

16 other study(ies) available for 3-hydroxybutyric acid and pentylenetetrazole

Article	Year
A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia, 1999, Volume: 40, Issue:2 Topics: 3-Hydroxybutyric Acid; Animals; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Epilepsy; Humans; Ketosis; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures	1999
Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. Epilepsy research, 1999, Volume: 35, Issue:1 Topics: 3-Hydroxybutyric Acid; Aging; Animals; Behavior, Animal; Convulsants; Diet; Energy Intake; Growth; Ketone Bodies; Ketosis; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures	1999
Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat. Developmental neuroscience, 1999, Volume: 21, Issue:3-5 Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Convulsants; Diet; Differential Threshold; Disease Susceptibility; Ketosis; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures	1999
Higher ketogenic diet ratios confer protection from seizures without neurotoxicity. Epilepsy research, 2000, Volume: 38, Issue:1 Topics: 3-Hydroxybutyric Acid; Animals; Basal Metabolism; Behavior, Animal; Convulsants; Diet; Dietary Fats; Dose-Response Relationship, Drug; Ketosis; Male; Neurotoxicity Syndromes; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Weight Gain	2000
A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. Epilepsy research, 2000, Volume: 38, Issue:2-3 Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Convulsants; Diet, Reducing; Dietary Fats; Electroshock; Energy Intake; Ketosis; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures	2000
The MCT ketogenic diet: effects on animal seizure models. Experimental neurology, 2000, Volume: 161, Issue:2 Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Body Weight; Dietary Fats, Unsaturated; Electroshock; Male; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Triglycerides	2000
Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet. Epilepsia, 2001, Volume: 42, Issue:10 Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Dietary Fats; Electroencephalography; Energy Intake; Male; Pentylenetetrazole; Phenytoin; Rats; Rats, Sprague-Dawley; Seizures; Treatment Outcome; Valproic Acid	2001
Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet. Epilepsy research, 2003, Volume: 54, Issue:1 Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Convulsants; Dietary Carbohydrates; Dietary Fats; Energy Intake; Ketone Bodies; Ketones; Male; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures	2003
A comparison of the ability of a 4:1 ketogenic diet and a 6.3:1 ketogenic diet to elevate seizure thresholds in adult and young rats. Epilepsia, 2005, Volume: 46, Issue:8 Topics: 3-Hydroxybutyric Acid; Age Factors; Animals; Blood Glucose; Body Weight; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Ketosis; Male; Pentylenetetrazole; Random Allocation; Rats; Rats, Wistar; Seizures; Treatment Outcome	2005
Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment. Epilepsia, 2008, Volume: 49, Issue:2 Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Caloric Restriction; Cerebral Cortex; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Electroencephalography; Energy Intake; Epilepsy; Ketosis; Male; Pentylenetetrazole; Rats; Rats, Wistar	2008
Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, exerts anticonvulsive properties. Epilepsia, 2009, Volume: 50, Issue:4 Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Body Weight; Diet, Ketogenic; Disease Models, Animal; Electroencephalography; Epilepsy; Fenofibrate; Hypolipidemic Agents; Ketone Bodies; Lithium Chloride; Liver; Male; Organ Size; Pentylenetetrazole; Pilocarpine; PPAR alpha; Rats; Rats, Wistar; Reaction Time	2009
Seizure tests distinguish intermittent fasting from the ketogenic diet. Epilepsia, 2010, Volume: 51, Issue:8 Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Anticonvulsants; Blood Glucose; Caloric Restriction; Diet, Ketogenic; Electroshock; Fasting; Kainic Acid; Male; Mice; Pentylenetetrazole; Seizures	2010
Anticonvulsant and proconvulsant actions of 2-deoxy-D-glucose. Epilepsia, 2010, Volume: 51, Issue:8 Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Anticonvulsants; Antimetabolites; Blood Glucose; Deoxyglucose; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Kainic Acid; Kindling, Neurologic; Male; Mice; Movement Disorders; Pentylenetetrazole; Rats; Seizures; Time Factors	2010
The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice. PloS one, 2012, Volume: 7, Issue:9 Topics: 3-Hydroxybutyric Acid; Acute Disease; Animals; Anticonvulsants; Blood Glucose; Blotting, Western; Cerebral Cortex; Dose-Response Relationship, Drug; Electroshock; Hippocampus; Immunosuppressive Agents; Injections, Intraperitoneal; Kainic Acid; Male; Mice; Pentylenetetrazole; Phosphorylation; Ribosomal Protein S6; Seizures; Sirolimus; Time Factors; TOR Serine-Threonine Kinases	2012
Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats. Brain research bulletin, 2016, Volume: 125 Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Blood Glucose; Body Weight; Convulsants; Diet, Ketogenic; Electroencephalography; gamma-Aminobutyric Acid; Male; Neurons; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Substantia Nigra	2016
Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency. eLife, 2022, 02-21, Volume: 11 Topics: 3-Hydroxybutyric Acid; Animals; Anion Transport Proteins; Biological Transport; Calcium; Gene Expression Regulation; Homeostasis; Ketone Bodies; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Monocarboxylic Acid Transporters; Neurons; Oxidation-Reduction; Pentylenetetrazole; Phosphorylation; Pyruvic Acid; Seizures; Tamoxifen	2022