3-hydroxybutyric acid and gamma-aminobutyric acid

3-hydroxybutyric acid has been researched along with gamma-aminobutyric acid in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's3 (11.54)18.2507
2000's5 (19.23)29.6817
2010's12 (46.15)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Abbe, R; Appel, SH; Bostwick, JR1
Bray, GA; Fisler, JS; Shimizu, H1
Fales, HM; Kaufman, EE; Levin, DM; Nelson, T1
Hauhart, RE; Thurston, JH1
Daikhin, Y; Grunstein, R; Nissim, I; Yudkoff, M1
Thio, LL; Wong, M; Yamada, KA1
Haber, S; Lapidot, A1
Gibson, KM1
Sonner, JM; Yang, L1
Fukuda, M; Hino, H; Ishii, E; Kobayashi, K; Suzuki, Y; Takahashi, H; Tanaka, J1
Bregestovski, P; Holmgren, CD; Malkov, AE; Mukhtarov, M; Popova, IY; Zilberter, Y1
Bergman, C; Clarke, K; Kashiwaya, Y; King, MT; Markis, W; Murray, A; Pawlosky, R; Srivastava, S; Veech, RL1
Holthoff, K; Kirmse, K; Witte, OW1
Allene, C; Ben-Ari, Y; Caiati, MD; Cherubini, E; Cossart, R; Ferré, P; Khalilov, I; Khazipov, R; Lorquin, J; Milh, M; Minlebaev, M; Nardou, R; Nehlig, A; Picardo, MA; Rheims, S; Romette, JL; Sivakumaran, S; Tyzio, R; Yamamoto, S1
Lund, TM; Obel, LF; Risa, Ø; Sonnewald, U1
Alger, BE; Kim, J; McCarthy, MM; Waddell, J1
Dahl, SR; Olsen, KM; Strand, DH1
Coppola, G; Iovane, V; Monda, M; Operto, FF; Pisano, S; Stoddard, M; Viggiano, A1
Archer, JR; Dargan, PI; Lambert, WE; Sadones, N; Stove, CP; Van Bever, E; Van Bortel, L; Wood, DM1
Hertz, L; Rothman, DL1
Goto, YI; Hashimoto, R; Hattori, K; Hayakawa, K; Kanba, S; Kaneko, S; Kang, D; Kato, TA; Kunugi, H; Miura, D; Ohgidani, M; Sagata, N; Sato-Kasai, M; Setoyama, D; Shimokawa, N; Yamamori, H; Yasuda, Y; Yoshida, S1
Haslberger, A; Peterlin, B; Zalar, B1
Behar, KL; de Graaf, RA; Dricot, L; Hyder, F; Koush, Y; Kupers, R; Ptito, M; Rothman, DL1
Behar, KL; de Graaf, RA; Hyder, F; Koush, Y; Rothman, DL1
Antal, B; Hone-Blanchet, A; Jenkins, BG; Lin, A; Lithen, A; McMahon, L; Mujica-Parodi, LR; Ratai, EM; Smith, NA; Stufflebeam, S; Yen, YF1
Baranovicova, E; Kalenska, D; Kovalska, M; Lehotsky, J1

Reviews

1 review(s) available for 3-hydroxybutyric acid and gamma-aminobutyric acid

ArticleYear
The Role of Microbiota in Depression - a brief review.
    Psychiatria Danubina, 2018, Volume: 30, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acylation; Brain; Butyrates; Depressive Disorder; DNA Methylation; Emotions; Epigenesis, Genetic; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gene Expression Regulation; Histones; Homeostasis; Humans; Neurotransmitter Agents; Serotonin Plasma Membrane Transport Proteins

2018

Other Studies

25 other study(ies) available for 3-hydroxybutyric acid and gamma-aminobutyric acid

ArticleYear
Phosphoethanolamine enhances high-affinity choline uptake and acetylcholine synthesis in dissociated cell cultures of the rat septal nucleus.
    Journal of neurochemistry, 1992, Volume: 59, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetylcholine; Animals; Cells, Cultured; Choline; Dopamine; Ethanolamines; gamma-Aminobutyric Acid; Hydroxybutyrates; Rats; Septal Nuclei; Sodium; Time Factors

1992
Brain 3-hydroxybutyrate, glutamate, and GABA in a rat model of dietary obesity.
    Physiology & behavior, 1989, Volume: 45, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Brain Chemistry; Corticosterone; Dietary Fats; Feeding Behavior; gamma-Aminobutyric Acid; Glutamates; Hydroxybutyrates; Insulin; Male; Obesity; Organ Size; Rats; Species Specificity

1989
Isolation and characterization of a hydroxyacid-oxoacid transhydrogenase from rat kidney mitochondria.
    The Journal of biological chemistry, 1988, Nov-15, Volume: 263, Issue:32

    Topics: 3-Hydroxybutyric Acid; Animals; Chromatography, Paper; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutarates; Hydrogen-Ion Concentration; Hydroxybutyrates; Kidney; Kinetics; Mitochondria; NAD; NADP; Rats; Sodium Oxybate; Time Factors

1988
Comparative effects of valproate and the new experimental anticonvulsant drug alpha-ethyl-alpha-methyl-thiobutyrolactone on selected metabolite levels in the plasma, livers, and brains of infant mice.
    Epilepsia, 1996, Volume: 37, Issue:1

    Topics: 3-Hydroxybutyric Acid; 4-Butyrolactone; Amino Acids; Animals; Animals, Suckling; Anticonvulsants; Blood Glucose; Brain Chemistry; Carnitine; Coenzyme A; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Hydroxybutyrates; Liver; Mice; Valproic Acid

1996
Effects of ketone bodies on astrocyte amino acid metabolism.
    Journal of neurochemistry, 1997, Volume: 69, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Aspartic Acid; Astrocytes; Cells, Cultured; Citric Acid; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Hydroxybutyrates; Ketone Bodies; Rats; Rats, Sprague-Dawley; Sheep

1997
Ketone bodies do not directly alter excitatory or inhibitory hippocampal synaptic transmission.
    Neurology, 2000, Jan-25, Volume: 54, Issue:2

    Topics: 3-Hydroxybutyric Acid; 4-Aminopyridine; Acetoacetates; Animals; Cells, Cultured; Diet; Entorhinal Cortex; Epilepsy; Evoked Potentials; Excitatory Amino Acid Agonists; Fasting; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Ketosis; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Receptors, AMPA; Receptors, GABA-A; Receptors, Glycine; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Synaptic Membranes; Synaptic Transmission

2000
Effect of endogenous beta-hydroxybutyrate on glucose metabolism in the diabetic rabbit brain: a (13)C-magnetic resonance spectroscopy study of [U-(13)C]glucose metabolites.
    Journal of neuroscience research, 2001, Apr-15, Volume: 64, Issue:2

    Topics: 3-Hydroxybutyric Acid; Alloxan; Amino Acids; Animals; Brain; Carbon Isotopes; Diabetes Mellitus, Experimental; Energy Metabolism; gamma-Aminobutyric Acid; Glucose; Ketones; Lactates; Magnetic Resonance Imaging; Nerve Tissue Proteins; Neuroglia; Neurons; Pyruvate Decarboxylase; Pyruvate Dehydrogenase Complex; Rabbits

2001
Gamma-hydroxybutyric aciduria: a biochemist's education from a heritable disorder of GABA metabolism.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:3

    Topics: 3-Hydroxybutyric Acid; Aldehyde Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Animals; gamma-Aminobutyric Acid; Humans; Mice; Succinate-Semialdehyde Dehydrogenase

2005
The anesthetic-like effects of diverse compounds on wild-type and mutant gamma-aminobutyric acid type A and glycine receptors.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:3

    Topics: 3-Hydroxybutyric Acid; Ammonium Chloride; Anesthetics; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Ethanol; Female; gamma-Aminobutyric Acid; Glycine; Humans; Isoflurane; Membrane Potentials; Oocytes; Point Mutation; Propofol; Rats; Receptors, GABA-A; Receptors, Glycine; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Xenopus laevis

2008
Beta-hydroxybutyrate alters GABA-transaminase activity in cultured astrocytes.
    Brain research, 2009, May-01, Volume: 1268

    Topics: 3-Hydroxybutyric Acid; 4-Aminobutyrate Transaminase; Analysis of Variance; Animals; Astrocytes; Butyric Acid; Cell Survival; Cells, Cultured; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glucose; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2009
Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro.
    Journal of neurochemistry, 2010, Volume: 112, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Bicarbonates; Energy Metabolism; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hydrogen-Ion Concentration; In Vitro Techniques; Ketone Bodies; Membrane Potentials; Models, Biological; Neocortex; Nerve Net; Neural Inhibition; Patch-Clamp Techniques; Pyruvic Acid; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Statistics, Nonparametric; Synaptic Transmission

2010
A ketone ester diet increases brain malonyl-CoA and Uncoupling proteins 4 and 5 while decreasing food intake in the normal Wistar Rat.
    The Journal of biological chemistry, 2010, Aug-20, Volume: 285, Issue:34

    Topics: 3-Hydroxybutyric Acid; Animals; Brain Chemistry; Butylene Glycols; Diet; Eating; Energy Metabolism; Esters; Fatty Acids; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channels; Ketone Bodies; Male; Malonyl Coenzyme A; Membrane Transport Proteins; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mitochondrial Uncoupling Proteins; Nerve Tissue Proteins; Palm Oil; Plant Oils; Rats; Rats, Wistar

2010
GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Nov-24, Volume: 30, Issue:47

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Drug Synergism; gamma-Aminobutyric Acid; Ketone Bodies; Membrane Potentials; Mice; Mice, Inbred C57BL; Neocortex; Neurons

2010
Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jan-05, Volume: 31, Issue:1

    Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Animals, Newborn; Bicuculline; Brain; Bumetanide; Calcium; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ketone Bodies; Lactic Acid; Male; Neurons; Patch-Clamp Techniques; Pyruvic Acid; Rats; Rats, Wistar; Signal Transduction; Sodium Potassium Chloride Symporter Inhibitors

2011
β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons.
    Neurochemistry international, 2011, Volume: 59, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Citric Acid Cycle; Female; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Homeostasis; Mice; Neurons; Nuclear Magnetic Resonance, Biomolecular; Pregnancy

2011
The depolarizing action of GABA in cultured hippocampal neurons is not due to the absence of ketone bodies.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Calcium; Cells, Cultured; Female; gamma-Aminobutyric Acid; Hippocampus; Ketone Bodies; Male; Muscimol; Neurons; Rats; Rats, Long-Evans

2011
Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Feb-15, Volume: 885-886

    Topics: 3-Hydroxybutyric Acid; 4-Butyrolactone; Butylene Glycols; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Humans; Illicit Drugs; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Sodium Oxybate; Tandem Mass Spectrometry

2012
Ketogenic diet prevents neuronal firing increase within the substantia nigra during pentylenetetrazole-induced seizure in rats.
    Brain research bulletin, 2016, Volume: 125

    Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Blood Glucose; Body Weight; Convulsants; Diet, Ketogenic; Electroencephalography; gamma-Aminobutyric Acid; Male; Neurons; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Substantia Nigra

2016
Microwave-assisted on-spot derivatization for gas chromatography-mass spectrometry based determination of polar low molecular weight compounds in dried blood spots.
    Journal of chromatography. A, 2016, Sep-23, Volume: 1465

    Topics: 3-Hydroxybutyric Acid; Amines; Butylene Glycols; Calibration; Cyclohexanecarboxylic Acids; Dried Blood Spot Testing; Forensic Toxicology; Gabapentin; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Hydroxybutyrates; Microwaves; Molecular Weight; Specimen Handling

2016
Glucose, Lactate, β-Hydroxybutyrate, Acetate, GABA, and Succinate as Substrates for Synthesis of Glutamate and GABA in the Glutamine-Glutamate/GABA Cycle.
    Advances in neurobiology, 2016, Volume: 13

    Topics: 3-Hydroxybutyric Acid; Acetates; Animals; Astrocytes; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Glutamine; Humans; Lactic Acid; Neurons; Succinates

2016
Plasma Metabolites Predict Severity of Depression and Suicidal Ideation in Psychiatric Patients-A Multicenter Pilot Analysis.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: 3-Hydroxybutyric Acid; Betaine; Biomarkers; Chromatography, Liquid; Citric Acid; Creatinine; Depression; Female; gamma-Aminobutyric Acid; Humans; Machine Learning; Male; Mass Spectrometry; Metabolomics; Pilot Projects; Psychiatric Status Rating Scales; Self Report; Severity of Illness Index; Suicidal Ideation

2016
Metabolic underpinnings of activated and deactivated cortical areas in human brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; Brain; Brain Mapping; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycolysis; Gyrus Cinguli; Humans; Lactic Acid; Magnetic Resonance Imaging; Male; Neurovascular Coupling; Visual Cortex

2021
Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2022, Volume: 42, Issue:6

    Topics: 3-Hydroxybutyric Acid; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Lactic Acid; Magnetic Resonance Imaging; Reproducibility of Results; Synaptic Transmission

2022
Acute administration of ketone beta-hydroxybutyrate downregulates 7T proton magnetic resonance spectroscopy-derived levels of anterior and posterior cingulate GABA and glutamate in healthy adults.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:5

    Topics: 3-Hydroxybutyric Acid; Adult; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Gyrus Cinguli; Humans; Ketones; Proton Magnetic Resonance Spectroscopy

2023
Hippocampal metabolic recovery as a manifestation of the protective effect of ischemic preconditioning in rats.
    Neurochemistry international, 2022, Volume: 160

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Choline; gamma-Aminobutyric Acid; Glutamates; Glutamine; Hippocampus; Humans; Ischemic Preconditioning; Prosencephalon; Rats; Rats, Wistar; Tissue Extracts

2022