3-hydroxybutyric acid and dapagliflozin

3-hydroxybutyric acid has been researched along with dapagliflozin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Cullen, MJ; Devenny, JJ; Godonis, HE; Harvey, SJ; Pelleymounter, MA; Rooney, S1
Dandona, P; Hansen, L; Henry, RR; Mudaliar, S; Pettus, J; Xu, J1
Aschemeier, B; Biester, T; Danne, T; Fath, M; Frey, M; Kordonouri, O; Scheerer, MF1
Baek, SI; Choi, SH; Jang, HC; Kim, KM; Lee, DH; Lim, S; Min, SH; Moon, JH; Oh, TJ; Park, KS1
Fukuhara, A; Nishitani, S; Okuno, Y; Otsuki, M; Shimomura, I; Shin, J1
Cho, HC; Choi, BY; Choi, SH; Jang, HC; Lee, JI; Lee, YK; Oh, TJ1
An, Y; Fu, P; Han, X; Liu, Y; Sun, F; Wang, C; Wang, N; Yu, X; Zhang, X; Zhang, Y1

Trials

2 trial(s) available for 3-hydroxybutyric acid and dapagliflozin

ArticleYear
Dapagliflozin in patients with type 1 diabetes: A post hoc analysis of the effect of insulin dose adjustments on 24-hour continuously monitored mean glucose and fasting β-hydroxybutyrate levels in a phase IIa pilot study.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:6

    Topics: 3-Hydroxybutyric Acid; Adult; Benzhydryl Compounds; Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fasting; Female; Glucose; Glucosides; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Pilot Projects

2017
Effects of dapagliflozin on insulin-requirement, glucose excretion and ß-hydroxybutyrate levels are not related to baseline HbA1c in youth with type 1 diabetes.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:11

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Benzhydryl Compounds; Child; Cross-Over Studies; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Glucosides; Glycated Hemoglobin; Glycosuria; Humans; Insulin; Male; Pilot Projects; Young Adult

2017

Other Studies

5 other study(ies) available for 3-hydroxybutyric acid and dapagliflozin

ArticleYear
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Blood Glucose; Caloric Restriction; Diet; Dose-Response Relationship, Drug; Drinking; Energy Intake; Glucosides; Hyperphagia; Insulin; Male; Obesity; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Respiration; Sodium-Glucose Transport Proteins; Treatment Outcome; Weight Loss

2012
Degree of ketonaemia and its association with insulin resistance after dapagliflozin treatment in type 2 diabetes.
    Diabetes & metabolism, 2018, Volume: 44, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Benzhydryl Compounds; Case-Control Studies; Diabetes Mellitus, Type 2; Glucosides; Humans; Hypoglycemic Agents; Insulin Resistance; Ketosis; Middle Aged; Young Adult

2018
Metabolomic and microarray analyses of adipose tissue of dapagliflozin-treated mice, and effects of 3-hydroxybutyrate on induction of adiponectin in adipocytes.
    Scientific reports, 2018, 06-11, Volume: 8, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adiponectin; Adipose Tissue; Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Gene Expression Profiling; Glucosides; Metabolome; Metabolomics; Mice; Mice, Inbred NOD; Microarray Analysis; Sodium-Glucose Transporter 2 Inhibitors; Transcriptome; Up-Regulation

2018
Complementary effects of dapagliflozin and lobeglitazone on metabolism in a diet-induced obese mouse model.
    European journal of pharmacology, 2023, Oct-15, Volume: 957

    Topics: 3-Hydroxybutyric Acid; Animals; Benzhydryl Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Heart Failure; Hypoglycemic Agents; Insulin; Mice; Mice, Obese; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Thiazolidinediones; Weight Gain

2023
Dapagliflozin Attenuates Heart Failure With Preserved Ejection Fraction Remodeling and Dysfunction by Elevating β-Hydroxybutyrate-activated Citrate Synthase.
    Journal of cardiovascular pharmacology, 2023, Nov-01, Volume: 82, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Animals; Citrate (si)-Synthase; Heart Failure; Humans; Male; Rats; Rats, Sprague-Dawley; Stroke Volume; Ventricular Remodeling

2023