3-hydroxybenzo(a)pyrene has been researched along with benzo(a)pyrene in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (25.00) | 18.7374 |
| 1990's | 12 (30.00) | 18.2507 |
| 2000's | 6 (15.00) | 29.6817 |
| 2010's | 11 (27.50) | 24.3611 |
| 2020's | 1 (2.50) | 2.80 |
| Authors | Studies |
|---|---|
| Dikun, PP; Filatov, VN; Likhachev, AIa; Savochkina, IV; Tyndyk, ML; Zabezhinskiĭ, MA | 1 |
| Beniashvili, DSh; Bykov, VJ; Dikun, PP; Likhachev, AJ; Savochkina, IV; Tyndyk, ML; Yermilov, VB; Zabezhinski, MA | 1 |
| Brauze, D; Kotecki, M; Mikstacka, R | 1 |
| Dikun, PP; Iamshanov, VA; Likhachev, AIa; Savochkina, IV; Zabezhinskiĭ, MA | 1 |
| Kiefer, F; Krupski, G; Schuller, HM; Wiebel, FJ | 1 |
| Glatt, H; Hirom, P; Kirkby, C; Oesch, F; Ribeiro, O; Seidel, A | 1 |
| Hirom, PC; Kirkby, CA; Millburn, P; Ribeiro, O | 1 |
| Bos, RP; Henderson, PT; Jongeneelen, FJ; Leijdekkers, CM; Theuws, JL | 1 |
| Baird, WM; Pruess-Schwartz, D | 1 |
| Nichols, AV; Shu, HP | 1 |
| Hicks, RM; Knowles, MA; Moore, BP; Redgrave, S | 1 |
| MacLeod, MC; Mansfield, BK; Selkirk, JK | 1 |
| D'Silva, AP; Fassel, VA; Walters, SN | 1 |
| Henderson, PT; Jongeneelen, FJ; Leijdekkers, CM | 1 |
| Williams, D; Woodhouse, K | 1 |
| Beniashvili, DSh; Bykov, VJ; Kazanova, OI; Likhachev, AJ; Loktionova, NA; Tyndyk, ML; Yatsuk, OS; Yermilov, VB; Zabezhinski, MA | 1 |
| Bouchard, M; Viau, C | 3 |
| Arimoto, S; Hayatsu, H; Kan-yama, K; Rai, H | 1 |
| Floot, B; Godschalk, RW; Kleinjans, JC; Kriek, E; Moonen, EJ; Schilderman, PA; van Schooten, FJ; Vermeer, IT | 1 |
| Jewell, CS; Mayeaux, MH; Winston, GW | 1 |
| Broekmans, WM; Godschalk, RW; Kleinjans, JC; Moonen, EJ; Schilderman, PA; Van Schooten, FJ | 1 |
| Jiang, W; Kondraganti, SR; Miller, KP; Moorthy, B; Ramos, KS; Williams, ES | 1 |
| Cao, D; Kim, CH; Park, ES; Shin, BS; Yoo, SD; Yoon, CH | 1 |
| Chen, J; Li, PJ; Shi, K; Yu, XC; Zang, SY; Zhang, H | 1 |
| Awooda, I; Barhoumi, R; Burghardt, RC; Catania, JM; Parrish, AR; Safe, S; Tiffany-Castiglioni, E | 1 |
| Beydon, D; Champmartin-Gendre, C; Ferrari, E; Lafontaine, M; Marquet, F; Payan, JP; Simon, P; Wathier, L | 1 |
| Bouchard, M; Heredia-Ortiz, R; Maître, A; Marie, C; Viau, C | 1 |
| Bouchard, M; Maître, A; Marie-Desvergne, C; Ravanat, JL; Viau, C | 1 |
| Cao, J; Guo, LH; Lin, Y; Wei, Y; Zhang, AQ | 1 |
| Bouchard, M; Heredia-Ortiz, R; Maître, A; Marie-Desvergne, C; Viau, C | 1 |
| Chien, YC; Yeh, CT | 1 |
| Angerer, J; Brüning, T; Käfferlein, HU; Marczynski, B; Pesch, B; Rihs, HP; Simon, P; Straif, K; Wilhelm, M | 1 |
| Bouchard, M; Heredia-Ortiz, R | 1 |
| Barbeau, D; Bouchard, M; Heredia Ortiz, R; Lafontaine, M; Maître, A | 1 |
| Bo, Y; Fa-Sheng, L; Gang, C; Hui, L; Jie, Z; Lin, Q; Min, S; Na, L; Xiao-Chen, L | 1 |
| Jennen, D; Kleinjans, J; Kyrtoupolos, S; Souza, T; van Delft, J; van Herwijnen, M | 1 |
| Campbell, J; Clewell, H; Crowell, S; Franzen, A; Gentry, R; Loccisano, A; Lumpkin, M; Meredith, C; Van Landingham, C | 1 |
| Deng, L; Deng, Q; Liu, H | 1 |
1 review(s) available for 3-hydroxybenzo(a)pyrene and benzo(a)pyrene
| Article | Year |
|---|---|
[Benzo(a)pyrene metabolism in human fibroblasts--effect of 7,8-benzoflavone].
Topics: Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Chromatography, High Pressure Liquid; Culture Media; Depression, Chemical; Fibroblasts; Humans; In Vitro Techniques | 1990 |
1 trial(s) available for 3-hydroxybenzo(a)pyrene and benzo(a)pyrene
| Article | Year |
|---|---|
Excretion kinetics of urinary 3-hydroxybenzo[a]pyrene following dietary exposure to benzo[a]pyrene in humans.
Topics: Adult; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Charcoal; Cooking; Dose-Response Relationship, Drug; Female; Humans; Male; Meat; Young Adult | 2012 |
38 other study(ies) available for 3-hydroxybenzo(a)pyrene and benzo(a)pyrene
| Article | Year |
|---|---|
[A comparative study of the individual characteristics of the excretion of metabolites of benzo(a)pyrene and its carcinogenic effect in rats].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Feces; Least-Squares Analysis; Male; Neoplasms, Experimental; Probability; Rats; Regression Analysis; Time Factors | 1992 |
Biomarkers for individual susceptibility to carcinogenic agents: excretion and carcinogenic risk of benzo[a]pyrene metabolites.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers, Tumor; Dihydroxydihydrobenzopyrenes; Disease Susceptibility; Feces; Histiocytoma, Benign Fibrous; Macaca fascicularis; Male; Peritoneal Neoplasms; Rats; Risk Factors; Species Specificity | 1992 |
[The individual characteristics of the excretion of benzo(a)pyrene metabolites in rats].
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Dihydroxydihydrobenzopyrenes; Feces; Male; Rats; Spectrometry, Fluorescence; Time Factors | 1990 |
Expression of glutathione S-transferase and phenol sulfotransferase, but not of UDP-glucuronosyltransferase, in the human lung tumor cell lines NCI-H322 and NCI-H358.
Topics: Arylsulfotransferase; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Survival; Fluorescence; Glucuronates; Glucuronidase; Glucuronosyltransferase; Glutathione Transferase; Humans; Hydroxylation; Lung Neoplasms; Phenols; Sulfurtransferases | 1986 |
Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cells, Cultured; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Microsomes, Liver; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Structure-Activity Relationship | 1987 |
Secondary metabolites of benzo[a]pyrene: 3-hydroxy-trans-7,8-dihydro-7,8-dihydroxybenzo[a]pyrene, a biliary metabolite of 3-hydroxybenzo[a]pyrene in the rat.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Bile; Dihydroxydihydrobenzopyrenes; Female; Rats; Rats, Inbred Lew; Spectrum Analysis | 1985 |
Excretion of 3-hydroxy-benzo(a)pyrene and mutagenicity in rat urine after exposure to benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Chromatography, High Pressure Liquid; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Spectrometry, Fluorescence; Time Factors | 1985 |
Benzo(a)pyrene:DNA adduct formation in early-passage Wistar rat embryo cell cultures: evidence for multiple pathways of activation of benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; DNA; Hydrolysis; In Vitro Techniques; Rats; Rats, Inbred Strains; Stereoisomerism | 1986 |
Uptake of lipophilic carcinogens by plasma lipoproteins. Structure-activity studies.
Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens; Dihydroxydihydrobenzopyrenes; Humans; Kinetics; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Structure-Activity Relationship | 1981 |
Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder.
Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Dihydroxydihydrobenzopyrenes; DNA; Epithelium; Female; Glucuronidase; Humans; Hydroxyacetylaminofluorene; Male; Organ Culture Techniques; Rats; Urinary Bladder | 1982 |
Time course of metabolism of benzo[e]pyrene by hamster embryo cells and the effect of chemical modifiers.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Carcinogens; Cells, Cultured; Cricetinae; Dihydroxydihydrobenzopyrenes; Embryo, Mammalian; Isomerism; Kinetics | 1982 |
Immobilized enzyme system for the conversion of benzo[a]pyrene to fluorescent metabolites.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Environment; Enzymes, Immobilized; In Vitro Techniques; Male; Methods; Microsomes, Liver; Mutagens; Rats; Spectrometry, Fluorescence | 1982 |
Urinary excretion of 3-hydroxy-benzo[a]pyrene after percutaneous penetration and oral absorption of benzo[a]pyrene in rats.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Skin Absorption; Time Factors | 1984 |
The relationship between age and cutaneous aryl hydrocarbon hydroxylase (AHH) activity.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Female; Male; Rats; Rats, Inbred BN; Rats, Wistar; Reference Values; Skin | 1995 |
Biomarkers of individual susceptibility to carcinogens: application for biological monitoring.
Topics: Adult; Age Factors; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Carcinogens; Child; Dihydroxydihydrobenzopyrenes; Disease Susceptibility; DNA; DNA Repair; Environmental Monitoring; Female; Gastric Juice; Gastric Mucosa; Gastritis; Humans; Lung Neoplasms; Macaca fascicularis; Male; Methyltransferases; Middle Aged; Nitroso Compounds; O(6)-Methylguanine-DNA Methyltransferase; Rats; Smoking; Stomach Neoplasms | 1993 |
Benzo(a)pyrenediolepoxide-hemoglobin adducts and 3-hydroxy-benzo(a)pyrene urinary excretion profiles in rats subchronically exposed to benzo(a)pyrene.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Carcinogens; Drug Administration Schedule; Half-Life; Hemoglobins; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley | 1995 |
Inhibitory effect of hemin, chlorophyllin and related pyrrole pigments on the mutagenicity of benzo[a]pyrene and its metabolites.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Antimutagenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Chlorophyllides; DNA Adducts; Ferric Compounds; Hemin; Metalloporphyrins; Mutagenicity Tests; Mutagens; Pigments, Biological; Pyrroles; Salmonella typhimurium | 1995 |
Urinary excretion kinetics of pyrene and benzo(a)pyrene metabolites following intravenous administration of the parent compounds or the metabolites.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Dihydroxydihydrobenzopyrenes; Half-Life; Injections, Intravenous; Kinetics; Male; Mutagens; Pyrenes; Rats; Rats, Sprague-Dawley; Urine | 1996 |
Comparison of 32P-postlabeling and HPLC-FD analysis of DNA adducts in rats acutely exposed to benzo(a)pyrene.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, High Pressure Liquid; DNA; DNA Adducts; Environmental Pollutants; Fluorescence; Kinetics; Liver; Lung; Male; Myocardium; Phosphorus Radioisotopes; Polycyclic Aromatic Hydrocarbons; Rats; Rats, Inbred Lew; Urine | 1997 |
Urinary excretion of benzo[a]pyrene metabolites following intravenous, oral, and cutaneous benzo[a]pyrene administration.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Benzo(a)pyrene; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Environmental Pollutants; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley | 1997 |
Benzo[a]pyrene metabolism by the hepatopancreas and green gland of the red swamp crayfish, Procambarus clarkii, in vitro.
Topics: Animals; Astacoidea; Benzo(a)pyrene; Benzopyrene Hydroxylase; Benzopyrenes; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Digestive System; Female; In Vitro Techniques; Male; Microsomes; Mixed Function Oxygenases; NADP; Rats | 1997 |
Exposure-route-dependent DNA adduct formation by polycyclic aromatic hydrocarbons.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; DNA Adducts; Environmental Exposure; Leukocytes; Male; Rats; Rats, Inbred Lew; Regression Analysis | 2000 |
Role of cytochrome P4501B1 in benzo[a]pyrene bioactivation to DNA-binding metabolites in mouse vascular smooth muscle cells: evidence from 32P-postlabeling for formation of 3-hydroxybenzo[a]pyrene and benzo[a]pyrene-3,6-quinone as major proximate genotoxi
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Cells, Cultured; Cytochrome P-450 CYP1B1; DNA; Mice; Muscle, Smooth, Vascular; Phosphorus Radioisotopes | 2003 |
Effects of aloe, aloesin, or propolis on the pharmacokinetics of benzo[a]pyrene and 3-OH-benzo[a]pyrene in rats.
Topics: Aloe; Animals; Benzo(a)pyrene; Benzopyrenes; Bile; Body Weight; Chromatography, High Pressure Liquid; Chromones; Feces; Glucosides; Male; Plant Extracts; Propolis; Rats; Rats, Sprague-Dawley; Urine | 2005 |
Degradation of metabolites of benzo[a]pyrene by coupling Penicillium chrysogenum with KMnO4.
Topics: Benzo(a)pyrene; Benzopyrenes; Biodegradation, Environmental; Dihydroxydihydrobenzopyrenes; Environmental Pollutants; Hydrogen-Ion Concentration; Indicators and Reagents; Penicillium chrysogenum; Potassium Permanganate | 2007 |
Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Cell Line, Tumor; Cyclosporine; Cytochrome P-450 CYP1A1; Humans; Microscopy, Fluorescence, Multiphoton; Time Factors | 2009 |
3-Hydroxybenzo(a)pyrene as a biomarker of dermal exposure to benzo(a)pyrene.
Topics: Administration, Cutaneous; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Carbon Radioisotopes; Carcinogens; Half-Life; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Skin; Skin Absorption | 2009 |
A toxicokinetic study to elucidate 3-hydroxybenzo(a)pyrene atypical urinary excretion profile following intravenous injection of benzo(a)pyrene in rats.
Topics: Animals; Area Under Curve; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, High Pressure Liquid; Half-Life; Injections, Intravenous; Kidney; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2010 |
Evaluation of DNA adducts, DNA and RNA oxidative lesions, and 3-hydroxybenzo(a)pyrene as biomarkers of DNA damage in lung following intravenous injection of the parent compound in rats.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 8-Hydroxy-2'-Deoxyguanosine; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; Injections, Intravenous; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; RNA; Tandem Mass Spectrometry; Time Factors | 2010 |
Evaluation of the noncovalent binding interactions between polycyclic aromatic hydrocarbon metabolites and human p53 cDNA.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; DNA Damage; DNA, Complementary; Environmental Pollutants; Humans; Mutagens; Polycyclic Aromatic Hydrocarbons; Pyrenes; Tumor Suppressor Protein p53 | 2010 |
Modeling of the internal kinetics of benzo(a)pyrene and 3-hydroxybenzo(a)pyrene biomarker from rat data.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Computer Simulation; Half-Life; Kinetics; Linear Models; Liver; Lung; Male; Models, Theoretical; Rats; Rats, Sprague-Dawley; Skin | 2011 |
Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: a null result in brief.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Body Burden; Carcinogens, Environmental; Case-Control Studies; Deoxyguanosine; DNA Adducts; DNA Breaks; Dose-Response Relationship, Drug; Humans; Naphthalenes; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Reproducibility of Results; Smoking; Time Factors | 2012 |
Understanding the linked kinetics of benzo(a)pyrene and 3-hydroxybenzo(a)pyrene biomarker of exposure using physiologically-based pharmacokinetic modelling in rats.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Computer Simulation; Humans; Kinetics; Least-Squares Analysis; Models, Biological; Occupational Exposure; Rats; Tissue Distribution | 2013 |
Use of physiologically-based pharmacokinetic modeling to simulate the profiles of 3-hydroxybenzo(a)pyrene in workers exposed to polycyclic aromatic hydrocarbons.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Environmental Monitoring; Humans; Models, Theoretical; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Rats | 2014 |
Quantitative analysis of 3-OHB[a]P and (+)-anti-BPDE as biomarkers of B[a]P exposure in rats.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Administration, Oral; Animals; Benzo(a)pyrene; Benzopyrenes; Biomarkers; Chromatography, High Pressure Liquid; Environmental Exposure; Limit of Detection; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2016 |
New insights into BaP-induced toxicity: role of major metabolites in transcriptomics and contribution to hepatocarcinogenesis.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Dihydroxydihydrobenzopyrenes; DNA Adducts; DNA Damage; Hep G2 Cells; Humans; Liver Neoplasms; Transcriptome | 2016 |
Predicting lung dosimetry of inhaled particleborne benzo[a]pyrene using physiologically based pharmacokinetic modeling.
Topics: Administration, Inhalation; Administration, Oral; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Humans; Inhalation Exposure; Lung; Models, Biological; Particulate Matter; Rats | 2016 |
Physiologically-based pharmacokinetic modeling of benzo(a)pyrene and the metabolite in humans of different ages.
Topics: Age Factors; Aging; Benzo(a)pyrene; Benzopyrenes; Drug Elimination Routes; Humans; Inhalation Exposure; Liver; Models, Biological; Organ Specificity | 2021 |