3-hydroxy-5-estrane-17-carbonitrile has been researched along with gamma-aminobutyric acid in 3 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Studies (3-hydroxy-5-estrane-17-carbonitrile) | Trials (3-hydroxy-5-estrane-17-carbonitrile) | Recent Studies (post-2010) (3-hydroxy-5-estrane-17-carbonitrile) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 17 | 0 | 2 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Covey, DF; Hu, Y; Zorumski, CF | 1 |
| Akk, G; Bracamontes, J; Steinbach, JH | 1 |
| Akk, G; Bracamontes, JR; Covey, DF; Dao, T; Evers, A; Steinbach, JH | 1 |
3 other study(ies) available for 3-hydroxy-5-estrane-17-carbonitrile and gamma-aminobutyric acid
| Article | Year |
|---|---|
Neurosteroid analogues: structure-activity studies of benz[e]indene modulators of GABAA receptor function. 1. The effect of 6-methyl substitution on the electrophysiological activity of 7-substituted benz[e]indene-3-carbonitriles.
Topics: Androstanols; Animals; Cells, Cultured; Chloride Channels; Computer Simulation; Electrophysiology; Estranes; gamma-Aminobutyric Acid; Hippocampus; Ion Channel Gating; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Neurons; Nitriles; Rats; Receptors, GABA; Structure-Activity Relationship | 1993 |
Pregnenolone sulfate block of GABA(A) receptors: mechanism and involvement of a residue in the M2 region of the alpha subunit.
Topics: Binding Sites; Cell Line; Estranes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Ligands; Membrane Potentials; Mutagenesis; Nitriles; Patch-Clamp Techniques; Pentobarbital; Piperidines; Pregnenolone; Receptors, GABA-A; Transfection | 2001 |
Neuroactive steroids have multiple actions to potentiate GABAA receptors.
Topics: Animals; Cell Line; Drug Synergism; Estranes; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Kidney; Mutagenesis; Nitriles; Norandrostanes; Rats; Receptors, GABA-A; Steroids | 2004 |