Page last updated: 2024-09-05

3-fluoronorepinephrine and 6-fluoronorepinephrine

3-fluoronorepinephrine has been researched along with 6-fluoronorepinephrine in 12 studies

Compound Research Comparison

Studies
(3-fluoronorepinephrine)
Trials
(3-fluoronorepinephrine)
Recent Studies (post-2010)
(3-fluoronorepinephrine)
Studies
(6-fluoronorepinephrine)
Trials
(6-fluoronorepinephrine)
Recent Studies (post-2010) (6-fluoronorepinephrine)
14005309

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adejare, A; Creveling, CR; Daly, JW; Gusovsky, F; Kirk, KL; Padgett, W1
Arendsen, DL; Basha, FZ; Bush, EN; DeBernardis, JF; Kerkman, DJ; Kyncl, JJ; McClellan, WJ; Winn, M1
Chen, BH; Chen, GT; Creveling, CR; Daly, JW; Gusovsky, F; King, M; Kirk, KL; Nie, JY1
Daly, JW; Haufe, G; Herbert, B; Kirk, KL; Laue, KW; Lu, SF; Oshunleti, O; Padgett, WL1
Brasili, L; Cantalamessa, F; Picchio, MT; Quaglia, W1
Antkowiak, R; Boehlert, C; Creveling, CR; Kirk, KL; Thakker, DR1
Dunwiddie, TV; Hoffer, BJ; Kirk, KL; Mueller, AL1
Auerbach, DA; Cantacuzene, D; Creveling, CR; Kirk, KL; Klein, DC1
Hauser, G; Kirk, KL; Parks, JM1
Cantacuzene, D; Creveling, CR; Goldberg, LI; Kirk, KL; Kohli, JD1
Cantacuzene, D; Creveling, CR; Kirk, KL; McNeal, ET1
Chen, BH; Davenport, R; Kirk, KL; Nie, JY; Pike, VW; Singh, M1

Other Studies

12 other study(ies) available for 3-fluoronorepinephrine and 6-fluoronorepinephrine

ArticleYear
Syntheses and adrenergic activities of ring-fluorinated epinephrines.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cerebral Cortex; Cyclic AMP; Dihydroalprenolol; Dioxanes; Epinephrine; Guinea Pigs; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1988
Conformationally defined adrenergic agents. 1. Design and synthesis of novel alpha 2 selective adrenergic agents: electrostatic repulsion based conformational prototypes.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:10

    Topics: Adrenergic alpha-Agonists; Animals; Chemical Phenomena; Chemistry, Physical; Electricity; Male; Molecular Conformation; Motion; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1985
Syntheses of 2,5- and 2,6-difluoronorepinephrine, 2,5-difluoroepinephrine, and 2,6-difluorophenylephrine: effect of disubstitution with fluorine on adrenergic activity.
    Journal of medicinal chemistry, 1993, Nov-26, Volume: 36, Issue:24

    Topics: Animals; Cell Membrane; Cerebral Cortex; Dioxanes; Epinephrine; Fluorine Compounds; Guinea Pigs; Inositol Phosphates; Norepinephrine; Phenylephrine; Prazosin; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Structure-Activity Relationship; Synaptosomes

1993
Syntheses of (R)- and (S)-2- and 6-fluoronorepinephrine and (R)- and (S)-2- and 6-fluoroepinephrine: effect of stereochemistry on fluorine-induced adrenergic selectivities.
    Journal of medicinal chemistry, 2000, Apr-20, Volume: 43, Issue:8

    Topics: Adrenergic beta-Agonists; Animals; Binding, Competitive; Cerebellum; Cerebral Cortex; Epinephrine; In Vitro Techniques; Norepinephrine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Stereoisomerism; Structure-Activity Relationship

2000
Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats.
    European journal of pharmacology, 1987, Dec-01, Volume: 144, Issue:2

    Topics: Animals; Guinea Pigs; Ileum; Male; Muscle Contraction; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Vas Deferens

1987
Regioselectivity of catechol O-methyltransferase. The effect of pH on the site of O-methylation of fluorinated norepinephrines.
    The Journal of biological chemistry, 1986, Jan-05, Volume: 261, Issue:1

    Topics: Binding Sites; Catechol O-Methyltransferase; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Methylation; Norepinephrine; Normetanephrine; Substrate Specificity

1986
Noradrenergic responses in rat hippocampus: electrophysiological actions of direct- and indirect-acting sympathomimetics in the in vitro slice.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:3

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Dextroamphetamine; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathomimetics; Tyramine

1982
Effects on fluorine analogs of norepinephrine on stimulation of cyclic adenosine 3',5'-monophosphate and binding to beta-adrenergic receptors in intact pinealocytes.
    Biochemical pharmacology, 1981, May-15, Volume: 30, Issue:10

    Topics: Animals; Animals, Newborn; Binding, Competitive; Cells, Cultured; Cyclic AMP; Kinetics; Norepinephrine; Pindolol; Pineal Gland; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta

1981
Differential effects of fluoronorepinephrines on phosphatidylinositol turnover in rat pinealocytes.
    Journal of neurochemistry, 1983, Volume: 41, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Norepinephrine; Phosphatidylinositols; Pineal Gland; Rats; Receptors, Adrenergic, alpha; Structure-Activity Relationship

1983
Effects of ring fluorination on the cardiovascular actions of dopamine and norepinephrine in the dog.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 213, Issue:3

    Topics: Animals; Blood Pressure; Dogs; Dopamine; Female; Hemodynamics; Male; Myocardial Contraction; Norepinephrine; Regional Blood Flow; Renal Artery; Structure-Activity Relationship; Vasodilation

1980
Influence of fluorine substitution on the site of enzymatic O-methylation of fluorinated norepinephrines.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:12

    Topics: Catechol O-Methyltransferase; Chemical Phenomena; Chemistry; Fluorine; Hydrogen-Ion Concentration; Methylation; Norepinephrine; Oxidation-Reduction

1981
Fluorinated dihydroxyphenylserines as potential biological precursors of fluorinated norepinephrines.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: Animals; Blood-Brain Barrier; Droxidopa; Fluorine; Indicators and Reagents; Molecular Structure; Norepinephrine

1998