Page last updated: 2024-09-02

3-deoxyglucosone and pyruvaldehyde

3-deoxyglucosone has been researched along with pyruvaldehyde in 64 studies

Compound Research Comparison

Studies
(3-deoxyglucosone)
Trials
(3-deoxyglucosone)
Recent Studies (post-2010)
(3-deoxyglucosone)
Studies
(pyruvaldehyde)
Trials
(pyruvaldehyde)
Recent Studies (post-2010) (pyruvaldehyde)
1868772,458341,447

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (18.75)18.2507
2000's16 (25.00)29.6817
2010's23 (35.94)24.3611
2020's13 (20.31)2.80

Authors

AuthorsStudies
Fujii, J; Hasuike, Y; Kawasaki, Y; Okado, A; Takahashi, M; Taniguchi, N; Teshima, T1
Deck, LM; Gomez, MS; Gonzales, DM; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Vander Jagt, TJ1
Asahi, M; Che, W; Higashiyama, S; Kaneto, H; Okado, A; Takahashi, M; Taniguchi, N1
Hamaoka, R; Koh, YH; Mizuno, H; Suzuki, K; Taniguchi, N1
Eriksson, UJ; Minhas, HS; Thornalley, PJ; Wentzel, P1
Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S1
Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Koh, YH; Suzuki, K; Taniguchi, N1
Kikuchi, S; Makita, Z; Miyata, T; Moriwaka, F; Shinpo, K; Tashiro, K1
Abordo, EA; Minhas, HS; Thornalley, PJ1
Langborg, A; Minhas, HS; Thornalley, PJ1
Kikuchi, S; Moriwaka, F; Ogata, A; Sasaki, H; Shinpo, K; Tashiro, K1
Argirov, OK; Thornalley, PJ; Yurek-George, A1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C1
Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A1
Jahan, I; Ng, R; Thornalley, PJ1
Beisswenger, PJ; Howell, SK; O'Dell, RM; Szwergold, BS; Touchette, AD; Wood, ME1
Nakamoto, M; Nakayama, M; Numata, M; Sakai, A; Takesawa, S1
Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M1
Inagi, R; Kurokawa, K; Miyata, T; Nangaku, M; Ueda, Y; van Ypersele de Strihou, C; Yoshino, A1
Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M1
Akagawa, M; Sasaki, T; Suyama, K1
Dohmae, N; Honke, K; Koh, YH; Miyamoto, Y; Park, YS; Suzuki, K; Takahashi, M; Takio, K; Taniguchi, N1
Beisswenger, P; Ruggiero-Lopez, D1
Beisswenger, PJ; Drummond, KS; Howell, SK; Mauer, M; Nelson, RG; Szwergold, BS1
Shapira, A; Shazman, A; Shimoni, E; Ungar, Y1
Chang, CD; Chang, DM; Chen, BG; Chern, CL; Huang, MH; Lee, CI; Lee, YJ; Liu, RH; Wang, HC; Wu, MY; Wu, TG1
Artlett, CM; Kappler, F; Loughlin, DT; Sassi-Gaha, S; Schwartz, ML; Su, B; Tobia, AM1
Higashi, T; Min, JZ; Toyo'oka, T; Yamamoto, M; Yu, HF1
Arena, E; Ballistreri, G; Fallico, B; Tomaselli, F1
Degen, J; Hellwig, M; Henle, T1
Schalkwijk, CG; Scheijen, JL1
Kokkinidou, S; Peterson, DG1
Artlett, CM; Loarca, L; Sassi-Gaha, S1
Rabbani, N; Thornalley, PJ2
Gazzani, G; Mascherpa, D; Papetti, A1
Distler, L; Georgieva, A; Huppert, J; Kenkel, I; Pischetsrieder, M1
Gökmen, V; Kocadağlı, T1
Hanssen, NM; Maessen, DE; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM1
Gökmen, V; Hamzalıoğlu, A2
Morales, FJ; Navarro, M2
Gökmen, V; Göncüoğlu Taş, N1
Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC1
Bergmans, DC; Schalkwijk, CG; van Bussel, BC; van de Poll, MC1
Haluzik, M; Kazdova, L; Malinska, H; Markova, I; Škop, V; Svoboda, P; Trnovska, J1
Gao, WY; Li, H; Liu, ZF; Ma, SB; Wang, XJ1
Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S1
Gao, WY; Li, H; Wang, XJ; Zhang, HX; Zhu, AH1
Alouffi, S; Khan, MWA1
Ahmad, K; Choi, I; Lee, EJ; Lee, YH; Shaikh, S1
Arena, E; Brighina, S; Fallico, B; Palmeri, R; Restuccia, C1
Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y1
Ahmad, S; Farooqui, A; Husain, A; Khanam, A; Rehman, S; Yusuf, MA1
Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q1
Auditore, A; Becker, AK; Fleming, T; Messlinger, K; Pischetsrieder, M; Reeh, PW; Sauer, SK1
Akhter, A; Kausar, MA; Saeed, M; Siddiqui, AJ; Singh, R1
Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ1
Furuhashi, T; Odani, H; Ogawa, T; Tanaka, T; Yoshioka, S1
Dagnelie, PC; Eussen, SJPM; Maasen, K; Opperhuizen, A; Schalkwijk, CG; Scheijen, JLJM; Stehouwer, CDA; van der Kallen, CJH; van Greevenbroek, MMJ1
Grune, T; Herpich, C; Kochlik, B; Norman, K; Ott, C; Raupbach, J; Weber, D1

Reviews

8 review(s) available for 3-deoxyglucosone and pyruvaldehyde

ArticleYear
Metformin inhibition of glycation processes.
    Diabetes & metabolism, 2003, Volume: 29, Issue:4 Pt 2

    Topics: Azepines; Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Metformin; Pyruvaldehyde; Randomized Controlled Trials as Topic

2003
Assay of methylglyoxal and glyoxal and control of peroxidase interference.
    Biochemical Society transactions, 2014, Volume: 42, Issue:2

    Topics: Animals; Deoxyglucose; Glyoxal; Humans; Models, Biological; Peroxidase; Pyruvaldehyde

2014
Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease.
    Biochemical and biophysical research communications, 2015, Mar-06, Volume: 458, Issue:2

    Topics: Aging; Aldehydes; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus; Glyoxal; Humans; Inflammation; Kidney Diseases; Models, Biological; Oxidative Stress; Pyruvaldehyde; Stress, Physiological

2015
Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness.
    International journal of molecular sciences, 2017, Feb-07, Volume: 18, Issue:2

    Topics: Biomarkers; Comorbidity; Critical Care; Critical Illness; Deoxyglucose; Glyoxal; Humans; Hypoxia; Inflammation; Multiple Organ Failure; Pyruvaldehyde; Stress, Physiological

2017
Dicarbonyls Generation, Toxicities, Detoxifications and Potential Roles in Diabetes Complications.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction

2020
Consequences of Dicarbonyl Stress on Skeletal Muscle Proteins in Type 2 Diabetes.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Extracellular Matrix Proteins; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Muscle, Skeletal; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction

2020
Glycation and Antioxidants: Hand in the Glove of Antiglycation and Natural Antioxidants.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Antigens, Neoplasm; Antioxidants; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lactoylglutathione Lyase; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappa B; Oxidative Stress; Plant Extracts; Polyphenols; Protein Carbonylation; Pyruvaldehyde; Signal Transduction

2020
The Role of Glyoxalase in Glycation and Carbonyl Stress Induced Metabolic Disorders.
    Current protein & peptide science, 2020, Volume: 21, Issue:9

    Topics: Aging; Deoxyglucose; Diabetes Mellitus; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Isoenzymes; Lactoylglutathione Lyase; Metabolic Diseases; Neurodegenerative Diseases; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Schiff Bases; Signal Transduction

2020

Trials

5 trial(s) available for 3-deoxyglucosone and pyruvaldehyde

ArticleYear
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
    Diabetes, 1999, Volume: 48, Issue:1

    Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome

1999
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors

2000
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia.
    Diabetes care, 2001, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Cross-Over Studies; Deoxyglucose; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Administration Schedule; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Lispro; Middle Aged; Postprandial Period; Pyruvaldehyde; Regression Analysis

2001
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde

2003
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
    Diabetic medicine : a journal of the British Diabetic Association, 2021, Volume: 38, Issue:9

    Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Glyoxal; Humans; Irbesartan; Male; Middle Aged; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors; Treatment Outcome

2021

Other Studies

51 other study(ies) available for 3-deoxyglucosone and pyruvaldehyde

ArticleYear
Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines.
    Biochemical and biophysical research communications, 1996, Aug-05, Volume: 225, Issue:1

    Topics: Apoptosis; Cell Line; Cell Nucleus; Deoxyglucose; DNA, Neoplasm; Flow Cytometry; Glutathione; HL-60 Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Macrophages; Oxidants; Pyruvaldehyde; Tumor Cells, Cultured

1996
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes.
    Biochemical pharmacology, 1997, Apr-25, Volume: 53, Issue:8

    Topics: Acrolein; Aldehydes; Amino Acids; Deoxyglucose; Enzyme Activation; Glutathione Reductase; Ketoses; Pyruvaldehyde; Spectrometry, Fluorescence

1997
Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in
    The Journal of biological chemistry, 1997, Jul-18, Volume: 272, Issue:29

    Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arteriosclerosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyglucose; Diabetic Angiopathies; Epidermal Growth Factor; Gene Expression; Guanidines; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Peroxides; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic

1997
Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucosone.
    Journal of biochemistry, 1998, Volume: 123, Issue:2

    Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Northern; Cell Survival; Deoxyglucose; Enzyme Activation; Flow Cytometry; Immunoblotting; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection

1998
Teratogenicity of 3-deoxyglucosone and diabetic embryopathy.
    Diabetes, 1998, Volume: 47, Issue:12

    Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glucose; Glyoxal; Hyperglycemia; Male; Pregnancy; Pyruvaldehyde; Rats; Teratogens

1998
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells.
    Advances in experimental medicine and biology, 1999, Volume: 463

    Topics: Aldehyde Reductase; Animals; Deoxyglucose; Flow Cytometry; Gene Expression; Glucose; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection

1999
Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases.
    Journal of neuroscience research, 1999, Jul-15, Volume: 57, Issue:2

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Synergism; Free Radical Scavengers; Glycation End Products, Advanced; Glycosylation; Neurodegenerative Diseases; Neurons; Oxidative Stress; Peroxides; Pyruvaldehyde; Rats; Rats, Sprague-Dawley

1999
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
    Biochemical pharmacology, 1999, Aug-15, Volume: 58, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidines; Hydrogen Peroxide; Macrophages; Mice; Necrosis; Nitroarginine; Oxidative Stress; Pyruvaldehyde

1999
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
    The Biochemical journal, 1999, Nov-15, Volume: 344 Pt 1

    Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin

1999
Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons.
    Brain research, 2000, Apr-07, Volume: 861, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Glutathione; Glycation End Products, Advanced; Guanidines; Motor Neurons; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Spinal Cord

2000
Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.
    Biochemical pharmacology, 2000, Jul-01, Volume: 60, Issue:1

    Topics: Deoxyglucose; Enzyme Inhibitors; Glyoxal; Guanidines; Kinetics; Pyruvaldehyde; Spectrophotometry; Triazines

2000
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9

    Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines

2000
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
    Journal of biochemistry, 2001, Volume: 129, Issue:4

    Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses

2001
Sodium sulfite and N-acetylcysteine: new additives to dialysate for inhibiting formation of glucose degradation products and advanced glycation end-products.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2001, Volume: 17

    Topics: Acetylcysteine; Collagen Type IV; Deoxyglucose; Dialysis Solutions; Fluorescence; Glucose; Glycation End Products, Advanced; Glyoxylates; Humans; In Vitro Techniques; Pyruvaldehyde; Serum Albumin; Sulfites

2001
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
    Journal of agricultural and food chemistry, 2002, Mar-27, Volume: 50, Issue:7

    Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship

2002
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
    Kidney international, 2002, Volume: 62, Issue:2

    Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Guanidines; Humans; In Vitro Techniques; Kidney Failure, Chronic; Lactoylglutathione Lyase; Membranes, Artificial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde; Yeasts

2002
Oxidative deamination of benzylamine by glycoxidation.
    Bioorganic & medicinal chemistry, 2003, Apr-03, Volume: 11, Issue:7

    Topics: Benzaldehydes; Benzylamines; Chelating Agents; Copper; Deamination; Deoxyglucose; Edetic Acid; Free Radical Scavengers; Glucose; Glucose Oxidase; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Metals; Nitrogen; Oxidation-Reduction; Oxygen; Pyruvaldehyde; Reactive Oxygen Species

2003
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.
    Free radical research, 2003, Volume: 37, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyglucose; Erythrocytes; Glutathione; Glutathione Peroxidase; Glyoxal; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Muscle, Smooth; Oxidative Stress; Peptides; Phenylglyoxal; Protein Binding; Pyruvaldehyde; Rats; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors

2003
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
    Diabetes, 2005, Volume: 54, Issue:11

    Topics: Adolescent; Adult; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Susceptibility; Glycated Hemoglobin; Humans; Indians, North American; Oxidative Stress; Pyruvaldehyde; Risk Factors

2005
Reducing the formation of glucose degradation products in peritoneal dialysis solutions by ultrahigh temperature ohmic heating.
    Molecular nutrition & food research, 2007, Volume: 51, Issue:4

    Topics: Deoxyglucose; Dialysis Solutions; Glucose; Glyoxal; Hot Temperature; Peritoneal Dialysis; Pyruvaldehyde

2007
A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry.
    Journal of chromatography. A, 2008, Sep-12, Volume: 1204, Issue:1

    Topics: Calibration; Deoxyglucose; Gas Chromatography-Mass Spectrometry; Glyoxal; Humans; Pyruvaldehyde

2008
Two dicarbonyl compounds, 3-deoxyglucosone and methylglyoxal, differentially modulate dermal fibroblasts.
    Matrix biology : journal of the International Society for Matrix Biology, 2010, Volume: 29, Issue:2

    Topics: Cell Line; Collagen; Deoxyglucose; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Humans; Integrin beta1; Protein Isoforms; Pyruvaldehyde; Skin; Transforming Growth Factor beta1

2010
Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.
    Analytical biochemistry, 2012, May-15, Volume: 424, Issue:2

    Topics: Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Female; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Limit of Detection; Male; Middle Aged; Nails; Phenylenediamines; Pyruvaldehyde; Reproducibility of Results; Signal-To-Noise Ratio; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
Survey of 1,2-dicarbonyl compounds in commercial honey of different floral origin.
    Journal of food science, 2011, Volume: 76, Issue:8

    Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Food Analysis; Furaldehyde; Glyoxal; Honey; Ketones; Limit of Detection; Phenols; Pyruvaldehyde

2011
1,2-dicarbonyl compounds in commonly consumed foods.
    Journal of agricultural and food chemistry, 2012, Jul-18, Volume: 60, Issue:28

    Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Diet; Food Analysis; Furaldehyde; Galactose; Pyruvaldehyde

2012
Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen.
    Clinical chemistry and laboratory medicine, 2014, Jan-01, Volume: 52, Issue:1

    Topics: Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glyoxal; Humans; Isotope Labeling; Perchlorates; Phenylenediamines; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors

2014
Response surface methodology as optimization strategy for reduction of reactive carbonyl species in foods by means of phenolic chemistry.
    Food & function, 2013, Volume: 4, Issue:7

    Topics: Animals; Cattle; Cooking; Deoxyglucose; Food Additives; Food Preservation; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Milk; Phenols; Pyruvaldehyde

2013
Two α-dicarbonyls downregulate migration, invasion, and adhesion of liver cancer cells in a p53-dependent manner.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2013, Volume: 45, Issue:11

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Deoxyglucose; Down-Regulation; Drug Therapy, Combination; Genes, p53; Humans; Liver Neoplasms; Neoplasm Invasiveness; Pyruvaldehyde

2013
Free α-dicarbonyl compounds in coffee, barley coffee and soy sauce and effects of in vitro digestion.
    Food chemistry, 2014, Dec-01, Volume: 164

    Topics: Chromatography, High Pressure Liquid; Coffea; Coffee; Cooking; Deoxyglucose; Diacetyl; Digestion; Glyoxal; Hordeum; Hot Temperature; Humans; Models, Biological; Pyruvaldehyde; Soy Foods

2014
Structure- and concentration-specific assessment of the physiological reactivity of α-dicarbonyl glucose degradation products in peritoneal dialysis fluids.
    Chemical research in toxicology, 2014, Aug-18, Volume: 27, Issue:8

    Topics: Animals; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyglucose; Dialysis Solutions; Galactose; Glucose; Glycation End Products, Advanced; Glyoxal; Ketoses; Mice; NIH 3T3 Cells; Peptides; Peritoneal Dialysis; Pyrones; Pyruvaldehyde; Ribonuclease, Pancreatic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Investigation of α-dicarbonyl compounds in baby foods by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.
    Journal of agricultural and food chemistry, 2014, Aug-06, Volume: 62, Issue:31

    Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Furaldehyde; Glyoxal; Humans; Infant Food; Infant Formula; Ketoses; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization

2014
Post-Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study.
    Diabetes care, 2015, Volume: 38, Issue:5

    Topics: Atherosclerosis; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glyoxal; Humans; Hyperglycemia; Male; Mass Spectrometry; Middle Aged; Postprandial Period; Pyruvaldehyde

2015
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
    Food & function, 2016, Jun-15, Volume: 7, Issue:6

    Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde

2016
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
    Food chemistry, 2017, Feb-15, Volume: 217

    Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum

2017
Maillard reaction and caramelization during hazelnut roasting: A multiresponse kinetic study.
    Food chemistry, 2017, Apr-15, Volume: 221

    Topics: Amino Acids; Cooking; Corylus; Deoxyglucose; Fructose; Furaldehyde; Glucose; Glyoxal; Kinetics; Maillard Reaction; Pyruvaldehyde; Sucrose

2017
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
    Diabetes care, 2017, Volume: 40, Issue:4

    Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides

2017
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
    Food research international (Ottawa, Ont.), 2017, Volume: 92

    Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Metformin attenuates myocardium dicarbonyl stress induced by chronic hypertriglyceridemia.
    Physiological research, 2018, 05-04, Volume: 67, Issue:2

    Topics: Animals; Deoxyglucose; Diet; Glutathione; Glyoxal; Hypertriglyceridemia; Hypoglycemic Agents; Lactoylglutathione Lyase; Male; Metformin; Myocardium; Pyruvaldehyde; Rats; Rats, Wistar; Stress, Physiological

2018
Elevated levels of α-dicarbonyl compounds in the plasma of type II diabetics and their relevance with diabetic nephropathy.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Feb-01, Volume: 1106-1107

    Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diacetyl; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde

2019
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
    Journal of agricultural and food chemistry, 2019, May-22, Volume: 67, Issue:20

    Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry

2019
Measurement of α-dicarbonyl compounds in human saliva by pre-column derivatization HPLC.
    Clinical chemistry and laboratory medicine, 2019, Nov-26, Volume: 57, Issue:12

    Topics: Adult; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde; Saliva

2019
Antibacterial activity of 1,2-dicarbonyl compounds and the influence of the in vitro assay system.
    Food chemistry, 2020, May-01, Volume: 311

    Topics: Anti-Bacterial Agents; Bacillus cereus; Deoxyglucose; Glyoxal; Kinetics; Microbial Sensitivity Tests; Pseudomonas fluorescens; Pyruvaldehyde; Salmonella enterica

2020
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
    Journal of the science of food and agriculture, 2020, Mar-30, Volume: 100, Issue:5

    Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature

2020
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
    Food chemistry, 2020, Jul-01, Volume: 317

    Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde

2020
5-Hydroxymethylfurfural accumulation plays a critical role on acrylamide formation in coffee during roasting as confirmed by multiresponse kinetic modelling.
    Food chemistry, 2020, Jul-15, Volume: 318

    Topics: Acrylamide; Amino Acids; Coffee; Deoxyglucose; Food-Processing Industry; Furaldehyde; Glucose; Glyoxal; Hot Temperature; Kinetics; Pyruvaldehyde; Sucrose

2020
Reactive dicarbonyl compounds cause Calcitonin Gene-Related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum.
    The Journal of biological chemistry, 2020, 05-08, Volume: 295, Issue:19

    Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Deoxyglucose; Drug Interactions; Inflammation; Mice; Mice, Inbred C57BL; Nerve Fibers; Peritoneum; Prostaglandins; Pyruvaldehyde; Skin; Temperature

2020
Increase in the peripheral blood methylglyoxal levels in 10% of hospitalized chronic schizophrenia patients.
    Nagoya journal of medical science, 2021, Volume: 83, Issue:1

    Topics: Adult; Biomarkers; Case-Control Studies; Chronic Disease; Deoxyglucose; Female; Glyoxal; Hospitalization; Humans; Male; Middle Aged; Pyruvaldehyde; Schizophrenia; Stress, Physiological

2021
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
    The American journal of clinical nutrition, 2022, 01-11, Volume: 115, Issue:1

    Topics: Aged; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diet; Diet Surveys; Dietary Exposure; Fasting; Female; Glycation End Products, Advanced; Glyoxal; Humans; Linear Models; Male; Mass Spectrometry; Middle Aged; Netherlands; Optical Imaging; Pyruvaldehyde; Skin

2022
Fasting Concentrations and Postprandial Response of 1,2-Dicarbonyl Compounds 3-Deoxyglucosone, Glyoxal, and Methylglyoxal Are Not Increased in Healthy Older Adults.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2022, 05-05, Volume: 77, Issue:5

    Topics: Aged; Animals; Deoxyglucose; Fasting; Female; Glucose; Glyoxal; Humans; Insulins; Magnesium Oxide; Male; Mice; Mice, Inbred C57BL; Pyruvaldehyde

2022