Page last updated: 2024-09-02

3-deoxyglucosone and lysine

3-deoxyglucosone has been researched along with lysine in 30 studies

Compound Research Comparison

Studies
(3-deoxyglucosone)
Trials
(3-deoxyglucosone)
Recent Studies (post-2010)
(3-deoxyglucosone)
Studies
(lysine)
Trials
(lysine)
Recent Studies (post-2010) (lysine)
18687737,44962211,213

Protein Interaction Comparison

ProteinTaxonomy3-deoxyglucosone (IC50)lysine (IC50)
Cationic amino acid transporter 3Homo sapiens (human)158

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (23.33)18.2507
2000's9 (30.00)29.6817
2010's12 (40.00)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y1
Mossine, VV; Prabhakaram, M1
Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S1
Breinholt, J; Christensen, M; Mortensen, SB; Skovsted, IC1
Izuhara, Y; Jadoul, M; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; van Ypersele de Strihou, C; Wada, T; Yamada, Y1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Langborg, A; Minhas, HS; Thornalley, PJ1
Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C1
Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K1
Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A1
Dimitrova, R; Hayashi, H; Ivanov, I; Mironova, R; Niwa, T1
Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M1
Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M1
Ahmed, N; Horiuchi, S; Jono, T; Lin, X; Nagai, R; Takeya, M; Thornalley, PJ1
Baynes, JW; Bleich, M; Busch, AE; Deemer, EK; Dingermann, T; Huber, J; Münch, G; Schäfer, S; Schmid, K; Somoza, V; Wihler, C1
Glomb, MA; Gobert, J1
Chen, XM; Kitts, DD1
Brouwers, O; de Vos-Houben, JM; Hageman, G; Janssen, BJ; Miyata, T; Niessen, PM; Schalkwijk, CG; Stehouwer, CD; van Nieuwenhoven, F1
Ahmad, S; Ashraf, JM; Choi, I; Jan, AT; Khan, RH; Lee, EJ; Rabbani, G1
Gökmen, V; Hamzalıoğlu, A1
Birch, HL; Collier, TA; de Leeuw, NH; Nash, A1
Morales, FJ; Navarro, M2
Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC1
Fokkens, BT; Los, LI; Mulder, DJ; Schalkwijk, CG; Scheijen, JL; Smit, AJ1
Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S1
Broers, NJH; Canaud, B; Christiaans, MHL; Cornelis, T; Gauly, A; Hermans, MMH; Konings, CJAM; Kooman, JP; Martens, RJH; Schalkwijk, CG; Scheijen, JLJM; Stifft, F; van der Sande, FM; Wirtz, JJJM1
Chen, X; Lai, Y; Lei, C; Liang, Z; Yang, Y; Yang, Z; Zeng, Y1
Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y1
Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q1

Trials

3 trial(s) available for 3-deoxyglucosone and lysine

ArticleYear
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors

2000
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde

2003
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.
    PloS one, 2019, Volume: 14, Issue:8

    Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis

2019

Other Studies

27 other study(ies) available for 3-deoxyglucosone and lysine

ArticleYear
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
    Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1

    Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley

1998
Characterization of a blue fluorophore isolated from in vitro reaction of N-proportional to-acetyllysine and 3-deoxyglucosone.
    Preparative biochemistry & biotechnology, 1998, Volume: 28, Issue:4

    Topics: Adult; Aged; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyglucose; Eye Proteins; Fluorescent Dyes; Hemoglobins; Humans; Lysine; Magnetic Resonance Spectroscopy; Middle Aged; Spectrometry, Fluorescence; Spectrometry, Mass, Fast Atom Bombardment

1998
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia

1998
Characterisation of a novel AGE-compound derived from lysine and 3-deoxyglucosone.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyglucose; Glycation End Products, Advanced; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment

1998
Accumulation of carbonyls accelerates the formation of pentosidine, an advanced glycation end product: carbonyl stress in uremia.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12

    Topics: Aged; Aldehydes; Arginine; Carboxylic Acids; Deoxyglucose; Depression, Chemical; Esters; Glycosylation; Guanidines; Humans; Ketones; Lysine; Maillard Reaction; Male; Middle Aged; Molecular Weight; Phenylhydrazines; Renal Dialysis; Thiadiazoles; Thiazolidines; Ultrafiltration; Uremia

1998
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
    The Biochemical journal, 1999, Nov-15, Volume: 344 Pt 1

    Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin

1999
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:9

    Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines

2000
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
    Diabetes care, 2000, Volume: 23, Issue:10

    Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines

2000
Evidence for non-enzymatic glycosylation in Escherichia coli.
    Molecular microbiology, 2001, Volume: 39, Issue:4

    Topics: Bacterial Proteins; Deoxyglucose; Dimerization; Escherichia coli; Fluorescence; Glycosylation; Humans; Imidazoles; Interferon-gamma; Lysine; Protein Processing, Post-Translational; Recombinant Proteins; Spectrometry, Fluorescence

2001
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
    Journal of agricultural and food chemistry, 2002, Mar-27, Volume: 50, Issue:7

    Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship

2002
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
    Journal of biochemistry, 2004, Volume: 136, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors

2004
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
    Diabetologia, 2005, Volume: 48, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence

2005
Degradation of glucose: reinvestigation of reactive alpha-Dicarbonyl compounds.
    Journal of agricultural and food chemistry, 2009, Sep-23, Volume: 57, Issue:18

    Topics: Deoxyglucose; Glucose; Glyoxal; Ketoses; Lysine; Maillard Reaction; Pentanes; Phenylenediamines; Quinoxalines

2009
Correlating changes that occur in chemical properties with the generation of antioxidant capacity in different sugar-amino acid Maillard reaction models.
    Journal of food science, 2011, Volume: 76, Issue:6

    Topics: Amino Acids; Antioxidants; Color; Deoxy Sugars; Deoxyglucose; Fructose; Glucose; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Ketoses; Kinetics; Lysine; Maillard Reaction; Models, Chemical; Pentoses; Ribose; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

2011
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
    International journal of molecular sciences, 2013, Jul-29, Volume: 14, Issue:8

    Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling

2013
Physicochemical analysis of structural alteration and advanced glycation end products generation during glycation of H2A histone by 3-deoxyglucosone.
    IUBMB life, 2014, Volume: 66, Issue:10

    Topics: Arginine; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyglucose; Fluorescence; Glycation End Products, Advanced; Glycosylation; Histones; Humans; Lysine; Spectroscopy, Fourier Transform Infrared

2014
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
    Food & function, 2016, Jun-15, Volume: 7, Issue:6

    Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde

2016
Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study.
    Biophysical chemistry, 2016, Volume: 218

    Topics: Animals; Arginine; Binding Sites; Collagen Type I; Cross-Linking Reagents; Deoxyglucose; Glycation End Products, Advanced; Imidazoles; Lysine; Models, Molecular; Molecular Dynamics Simulation; Rats

2016
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
    Food chemistry, 2017, Feb-15, Volume: 217

    Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum

2017
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
    Diabetes care, 2017, Volume: 40, Issue:4

    Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides

2017
Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls.
    PloS one, 2017, Volume: 12, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Retinal Detachment

2017
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
    Food research international (Ottawa, Ont.), 2017, Volume: 92

    Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry

2017
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
    Journal of agricultural and food chemistry, 2019, May-22, Volume: 67, Issue:20

    Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry

2019
Pyrraline Formation Modulated by Sodium Chloride and Controlled by Encapsulation with Different Coating Materials in the Maillard Reaction.
    Biomolecules, 2019, 11-10, Volume: 9, Issue:11

    Topics: Amylose; Deoxyglucose; Glucose; Glycation End Products, Advanced; Hot Temperature; Lysine; Maillard Reaction; Norleucine; Pyrroles; Sodium Chloride; Zea mays

2019
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
    Journal of the science of food and agriculture, 2020, Mar-30, Volume: 100, Issue:5

    Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature

2020
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
    Food chemistry, 2020, Jul-01, Volume: 317

    Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde

2020