Page last updated: 2024-09-02

3-deoxyglucosone and epalrestat

3-deoxyglucosone has been researched along with epalrestat in 2 studies

Compound Research Comparison

Studies
(3-deoxyglucosone)
Trials
(3-deoxyglucosone)
Recent Studies (post-2010)
(3-deoxyglucosone)
Studies
(epalrestat)
Trials
(epalrestat)
Recent Studies (post-2010) (epalrestat)
18687724322100

Protein Interaction Comparison

ProteinTaxonomy3-deoxyglucosone (IC50)epalrestat (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)7.9635
Multidrug resistance-associated protein 4Homo sapiens (human)6.5
Aldo-keto reductase family 1 member B10Homo sapiens (human)0.1836
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.5596
Aldo-keto reductase family 1 member A1Homo sapiens (human)2.6
Aldo-keto reductase family 1 member B1Homo sapiens (human)0.1335
Aldo-keto reductase family 1 member B1Bos taurus (cattle)0.17
Cytochrome P450 2C19Homo sapiens (human)0.085
Aldo-keto reductase family 1 member A1Sus scrofa (pig)1.5
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)1.5
Aldo-keto reductase family 1 member B7Rattus norvegicus (Norway rat)1.198

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Araki, N; Hamada, Y; Horiuchi, S; Hotta, N1
Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K1

Other Studies

2 other study(ies) available for 3-deoxyglucosone and epalrestat

ArticleYear
Role of polyol pathway in nonenzymatic glycation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aldehyde Reductase; Animals; Cattle; Deoxyglucose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Erythrocytes; Fructosephosphates; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Polymers; Rhodanine; Serum Albumin, Bovine; Thiazolidines

1996
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
    Diabetes care, 2000, Volume: 23, Issue:10

    Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines

2000