3-deoxyglucosone has been researched along with deoxyglucose in 169 studies
| Studies (3-deoxyglucosone) | Trials (3-deoxyglucosone) | Recent Studies (post-2010) (3-deoxyglucosone) | Studies (deoxyglucose) | Trials (deoxyglucose) | Recent Studies (post-2010) (deoxyglucose) |
|---|---|---|---|---|---|
| 186 | 8 | 77 | 11,426 | 171 | 1,375 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.18) | 18.7374 |
| 1990's | 43 (25.44) | 18.2507 |
| 2000's | 43 (25.44) | 29.6817 |
| 2010's | 64 (37.87) | 24.3611 |
| 2020's | 17 (10.06) | 2.80 |
| Authors | Studies |
|---|---|
| Baynes, JW; Feather, MS; Knecht, KJ | 1 |
| Deyashiki, Y; Hara, A; Kanazu, T; Nakayama, T; Sawada, H; Shinoda, M | 1 |
| Baba, S; Hata, H; Igaki, N; Kato, H; Oimomi, M; Sakai, M | 1 |
| Brown, TR; Kappler, F; Szwergold, BS | 1 |
| Hayase, F; Kato, H; Sekiya, F; Shinoda, T; van Chuyen, N | 1 |
| Baba, S; Hata, F; Igaki, N; Nakamichi, T; Ohara, T; Oimomi, M; Sakai, M | 1 |
| Baba, S; Hayase, F; Kato, H; Oimomi, M; Shin, DB | 1 |
| Baynes, JW; Brown, TR; Kappler, F; Lal, S; Randall, WC; Szwergold, BS; Taylor, AH; Wells-Knecht, K | 1 |
| Maeda, K; Miyazaki, T; Niimura, K; Niwa, T; Ohara, M; Takeda, N; Tatematsu, A; Tomiyama, S; Yoshizumi, H | 1 |
| Fujii, J; Lu, YB; Myint, T; Takahashi, M; Taniguchi, N; Wada, Y | 1 |
| Fujii, E; Hotta, K; Ishii-Karakasa, I; Iwase, H; Yajima, Y | 1 |
| Monnier, VM; Nagaraj, RH; Portero-Otin, M | 1 |
| Igaki, N; Kasuga, M; Miyata, S; Miyauchi, Y; Ohara, T; Oimomi, M; Sakai, M; Shoda, H; Yamada, H; Yatabe, H | 1 |
| Fischer, P; Glomb, M; Lederer, M; Ledl, F | 1 |
| Deyashiki, Y; Hara, A; Inazu, A; Nakayama, T; Sato, K; Sawada, H; Yamaguchi, S | 1 |
| Nagaraj, RH; Sady, C | 1 |
| Katsuzaki, T; Maeda, K; Miyazaki, S; Miyazaki, T; Momoi, T; Niwa, T; Ogawa, H; Saito, A; Takei, Y; Tatemichi, N | 1 |
| Asahi, M; Fujii, J; Higashiyama, S; Kaneto, H; Kayanoki, Y; Suzuki, K; Takahashi, M; Taniguchi, N; Wenyi, C | 1 |
| Fujii, J; Hasuike, Y; Kawasaki, Y; Okado, A; Takahashi, M; Taniguchi, N; Teshima, T | 1 |
| Deyashiki, Y; Hara, A; Matsuura, K; Nakanishi, M; Sato, K | 1 |
| Katsuzaki, T; Miyazaki, T; Niwa, T; Takei, Y; Tatemichi, N | 1 |
| Araki, N; Hamada, Y; Horiuchi, S; Hotta, N | 1 |
| Deck, LM; Gomez, MS; Gonzales, DM; Hunsaker, LA; Royer, RE; Vander Jagt, DL; Vander Jagt, TJ | 1 |
| Hayase, F; Ishizaki, Y; Katsuzaki, T; Miyazaki, T; Niwa, T; Takei, Y; Tatemichi, N; Uematsu, T | 1 |
| Beisswenger, PJ; Brown, TR; Kappler, F; Lal, S; Orchard, TJ; Szwergold, BS; Walker, M | 1 |
| Asahi, M; Che, W; Higashiyama, S; Kaneto, H; Okado, A; Takahashi, M; Taniguchi, N | 1 |
| Niwa, T | 1 |
| Bahner, U; Heidland, A; Keis, R; Lemke, HD; Münch, G; Niwa, T; Riederer, P; Schinzel, R; Wessels, A | 1 |
| Brown, TR; Kappler, F; Lal, S; Randall, WC; Szwergold, BS; Taylor, AH; Walker, M | 1 |
| Araki, A | 1 |
| Hamaoka, R; Koh, YH; Mizuno, H; Suzuki, K; Taniguchi, N | 1 |
| Kurokawa, K; Mitsuma, T; Miyata, T; Niwa, H; Sobue, G; Takeda, A; Wakai, M; Yasuda, Y | 1 |
| Mossine, VV; Prabhakaram, M | 1 |
| Eriksson, UJ; Minhas, HS; Thornalley, PJ; Wentzel, P | 1 |
| Aoyama, I; Hirasawa, Y; Miyazaki, S; Miyazaki, T; Morita, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| Breinholt, J; Christensen, M; Mortensen, SB; Skovsted, IC | 1 |
| Izuhara, Y; Jadoul, M; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; van Ypersele de Strihou, C; Wada, T; Yamada, Y | 1 |
| Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD | 1 |
| Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Koh, YH; Suzuki, K; Taniguchi, N | 1 |
| Kikuchi, S; Makita, Z; Miyata, T; Moriwaka, F; Shinpo, K; Tashiro, K | 1 |
| Abordo, EA; Minhas, HS; Thornalley, PJ | 1 |
| Niwa, T; Shimokata, K; Tsukushi, S | 1 |
| Langborg, A; Minhas, HS; Thornalley, PJ | 1 |
| Gejyo, F; Hashimoto, N; Naiki, H | 1 |
| Kikuchi, S; Moriwaka, F; Ogata, A; Sasaki, H; Shinpo, K; Tashiro, K | 1 |
| Argirov, OK; Thornalley, PJ; Yurek-George, A | 1 |
| Asahi, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; VAN Ypersele DE Strihou, C | 1 |
| Baumann, M; Lederer, MO | 1 |
| Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K | 1 |
| Goffin, E; Inagi, R; Ishibashi, Y; Izuhara, Y; Kurokawa, K; Miyata, T; Saito, A; Ueda, Y; Van Ypersele De Strihou, C; Yoshino, A | 1 |
| Niwa, T; Tsukushi, S | 1 |
| Dimitrova, R; Hayashi, H; Ivanov, I; Mironova, R; Niwa, T | 1 |
| Jahan, I; Ng, R; Thornalley, PJ | 1 |
| Beisswenger, PJ; Howell, SK; O'Dell, RM; Szwergold, BS; Touchette, AD; Wood, ME | 1 |
| Nakamoto, M; Nakayama, M; Numata, M; Sakai, A; Takesawa, S | 1 |
| Bucala, R; Kameda, Y; Makita, Z; Matsuura, N; Takeuchi, M; Yamagishi Si, S; Yanase, Y | 1 |
| Becker, CM; Humeny, A; Kislinger, T; Pischetsrieder, M | 1 |
| Brown, T; Kappler, F; Schwartz, ML; Su, B; Tobia, AM | 1 |
| Inagi, R; Kurokawa, K; Miyata, T; Nangaku, M; Ueda, Y; van Ypersele de Strihou, C; Yoshino, A | 1 |
| Kajita, M; Nakamura, S; Niwa, T; Tsukushi, S | 1 |
| Hasuike, Y; Nakanishi, T; Nanami, M; Otaki, Y; Takamitsu, Y; Taniguchi, N; Tanimoto, T | 1 |
| Bahner, U; Deppisch, R; Haug, U; Henle, T; Ritz, E; Schneider, H; Schwenger, V; Wanner, C; Weigel, K; Zeier, M | 1 |
| Akagawa, M; Sasaki, T; Suyama, K | 1 |
| Dohmae, N; Honke, K; Koh, YH; Miyamoto, Y; Park, YS; Suzuki, K; Takahashi, M; Takio, K; Taniguchi, N | 1 |
| Inaba, K; Kasuga, M; Kojima, H; Kusunoki, H; Liu, BF; Miyata, S; Miyazaki, H; Ohara, T; Suzuki, K; Uriuhara, A; Yamashita, Y | 1 |
| Hoffman, WH; Kappler, F; Mehta, R; Passmore, GG | 1 |
| Beisswenger, P; Ruggiero-Lopez, D | 1 |
| Hiraku, Y; Kawanishi, S; Mizutani, M; Murata, M; Oikawa, S | 1 |
| Brown, KA; Brown, TR; Kappler, F; Schwartz, MA; Su, B; Tobia, AM | 1 |
| Akiyama, N; Hamada, Y; Hirooka, H; Horiuchi, S; Hotta, N; Kamiya, H; Li, W; Nakamura, J; Nakashima, E; Naruse, K; Oiso, Y; Takahashi, N | 1 |
| Kagawa, H; Kagawa, K | 1 |
| Aoyama, M; Endo, T; Ito, S; Kurano, Y; Uchida, Y | 1 |
| Nakamura, S; Niwa, T | 1 |
| Ahmed, N; Horiuchi, S; Jono, T; Lin, X; Nagai, R; Takeya, M; Thornalley, PJ | 1 |
| Bender, TO; Fleischmann, EH; Jörres, A; Niwa, T; Pischetsrieder, M; Tauer, A | 1 |
| Kasuga, M; Miyata, S | 1 |
| Baynes, JW; Bleich, M; Busch, AE; Deemer, EK; Dingermann, T; Huber, J; Münch, G; Schäfer, S; Schmid, K; Somoza, V; Wihler, C | 1 |
| Beisswenger, PJ; Drummond, KS; Howell, SK; Mauer, M; Nelson, RG; Szwergold, BS | 1 |
| Lee, SH; Misonou, Y; Miyamoto, Y; Sakiyama, H; Takahashi, M; Taniguchi, N; Teshima, T; Yamamoto, T | 1 |
| Benito, A; Justo, P; Kjellstrand, P; Linden, T; Ortiz, A; Sanchez-Niño, MD; Santamaria, B; Sanz, A; Wieslander, A | 1 |
| Collard, F; Duester, G; Fortpied, J; Van Schaftingen, E; Vertommen, D | 1 |
| Shapira, A; Shazman, A; Shimoni, E; Ungar, Y | 1 |
| Aida, K; Arai, Y; Hayase, F; Kawabata, R; Kishimoto, J; Ohguchi, M; Usui, T; Watanabe, H; Yanagisawa, S; Yoshino, M | 1 |
| Bravo, A; Herrera, JC; Ju-Nam, Y; Madrid, J; Rangel-Aldao, R; Rübsam, H; Scherer, E; Zufall, C | 1 |
| Chang, CD; Chang, DM; Chen, BG; Chern, CL; Huang, MH; Lee, CI; Lee, YJ; Liu, RH; Wang, HC; Wu, MY; Wu, TG | 1 |
| Imaizumi, T; Matsui, J; Matsuki, K; Murakami, H; Satoh, K; Suda, T; Tamasawa, N; Tanabe, J; Yamashita, M | 1 |
| Glomb, MA; Gobert, J | 1 |
| Artlett, CM; Kappler, F; Loughlin, DT; Sassi-Gaha, S; Schwartz, ML; Su, B; Tobia, AM | 1 |
| El-Kabbani, O; Endo, S; Hara, A; Kitade, Y; Kuragano, T; Matsunaga, T; Ohno, S; Tajima, K | 1 |
| Degen, J; Hellwig, M; Henle, T | 2 |
| Barto, R; Engelen, L; Ferreira, I; Gram, J; Lund, SS; Parving, HH; Pedersen, O; Schalkwijk, CG; Stehouwer, CD; Tarnow, L; Teerlink, T; Vaag, AA; Winther, K | 1 |
| Kwak, EJ; Lee, BY; Lee, OH; Lim, SI | 1 |
| Artlett, CM; Loughlin, DT | 1 |
| Chen, XM; Kitts, DD | 1 |
| Bols, M; Jadhav, H; Pedersen, CM; Sølling, T | 1 |
| Carmichael, I; Serianni, AS; Zhang, W | 1 |
| Mittelmaier, S; Niwa, T; Pischetsrieder, M | 1 |
| Higashi, T; Min, JZ; Toyo'oka, T; Yamamoto, M; Yu, HF | 1 |
| Arena, E; Ballistreri, G; Fallico, B; Tomaselli, F | 1 |
| Schalkwijk, CG; Scheijen, JL | 1 |
| Kokkinidou, S; Peterson, DG | 1 |
| Brouwers, O; de Vos-Houben, JM; Hageman, G; Janssen, BJ; Miyata, T; Niessen, PM; Schalkwijk, CG; Stehouwer, CD; van Nieuwenhoven, F | 1 |
| Artlett, CM; Loarca, L; Sassi-Gaha, S | 1 |
| Beyer, H; Degen, J; Hellwig, M; Henle, T; Heymann, B | 1 |
| Rabbani, N; Thornalley, PJ | 2 |
| Gazzani, G; Mascherpa, D; Papetti, A | 1 |
| Distler, L; Georgieva, A; Huppert, J; Kenkel, I; Pischetsrieder, M | 1 |
| Gökmen, V; Kocadağlı, T | 1 |
| Castro Vazquez, L; Hernández-Hernández, O; Martínez-Castro, I; Ruiz-Matute, AI; Sanz, ML | 1 |
| Ahmad, S; Ashraf, JM; Choi, I; Jan, AT; Khan, RH; Lee, EJ; Rabbani, G | 1 |
| Ahmad, S; Alam, K; Ashraf, JM; Choi, I; Hasan, Q; Jan, AT; Khan, RH; Lee, EJ; Rabbani, G | 1 |
| Hanssen, NM; Maessen, DE; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM | 1 |
| Cornelis, T; Eloot, S; Glorieux, G; Kooman, JP; Leunissen, KM; Schalkwijk, CG; Scheijen, JL; van der Sande, FM; Vanholder, R | 1 |
| Freund, J; Hellwig, A; Hellwig, M; Henle, T; Herder, C; Hoffmann, B; Krämer, U; Luckhaus, C; Peßler, A; Roden, M; Schikowski, T; Schulte, T; Sugiri, D; Teichert, T; Vierkötter, A; Vossoughi, M | 1 |
| Ahmad, S; Alam, K; Ashraf, JM; Choi, I; Hasan, Q; Khan, RH; Rabbani, G | 1 |
| Jiang, G; Liang, G; Song, X; Wang, F; Xu, H; Zhang, L; Zhou, L | 2 |
| Ahmad, S; Ashraf, JM; Aslam Yusuf, M; Choi, I; Lee, EJ; Shahab, U; Tabrez, S | 1 |
| Gökmen, V; Hamzalıoğlu, A | 2 |
| Hellwig, M; Henle, T; Nobis, A; Witte, S | 1 |
| Jiang, G; Liang, G; Qian, Z; Song, X; Wang, F; Zhang, L | 1 |
| Birch, HL; Collier, TA; de Leeuw, NH; Nash, A | 1 |
| Morales, FJ; Navarro, M | 2 |
| Gökmen, V; Göncüoğlu Taş, N | 1 |
| Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC | 1 |
| Bergmans, DC; Schalkwijk, CG; van Bussel, BC; van de Poll, MC | 1 |
| Fokkens, BT; Los, LI; Mulder, DJ; Schalkwijk, CG; Scheijen, JL; Smit, AJ | 1 |
| An, X; Zhang, Y | 1 |
| Aengevaeren, VL; Eijsvogels, TMH; Hopman, MTE; Maessen, MFH; Schalkwijk, CG; Verheggen, RJHM | 1 |
| Huang, F; Jiang, G; Liang, G; Song, X; Wang, F; Xu, Z; Zhang, L; Zhou, L | 1 |
| Lawrence, GD; Makahleh, A; Rahmat, R; Saad, B | 1 |
| Haluzik, M; Kazdova, L; Malinska, H; Markova, I; Škop, V; Svoboda, P; Trnovska, J | 1 |
| Gensberger-Reigl, S; Hellwig, M; Henle, T; Pischetsrieder, M | 1 |
| Huang, F; Jiang, G; Liang, G; Song, X; Wang, F; Zhang, L; Zhou, L | 1 |
| El-Maghrabey, MH; Kishikawa, N; Kuroda, N; Nakatani, T | 1 |
| Cai, J; Huang, F; Jiang, GR; Liang, GQ; Song, XD; Wang, F; Xu, H; Zhang, LR; Zhou, L | 1 |
| Gao, WY; Li, H; Liu, ZF; Ma, SB; Wang, XJ | 1 |
| Atzenbeck, L; Gensberger-Reigl, S; Göttler, A; Pischetsrieder, M | 1 |
| Gao, J; Han, Z; Li, J; Wang, S; Yang, Y; Zhang, Y | 1 |
| Paravisini, L; Peterson, DG | 1 |
| Becker, T; Gastl, M; Hellwig, M; Henle, T; Nobis, A; Röhrig, A | 1 |
| Bruhns, P; Degenhardt, AG; Kanzler, C; Koch, TJ; Kroh, LW | 1 |
| Degen, J; Henle, T; Löbner, J; Spengler, F; Treibmann, S | 1 |
| Huang, F; Jiang, G; Liang, G; Shi, M; Song, X; Wang, F; Zhang, L; Zhou, L | 2 |
| Huang, F; Jiang, G; Liang, G; Song, X; Wang, F; Xu, H; Zhang, L; Zhou, L | 1 |
| Gao, WY; Li, H; Wang, XJ; Zhang, HX; Zhu, AH | 1 |
| Broers, NJH; Canaud, B; Christiaans, MHL; Cornelis, T; Gauly, A; Hermans, MMH; Konings, CJAM; Kooman, JP; Martens, RJH; Schalkwijk, CG; Scheijen, JLJM; Stifft, F; van der Sande, FM; Wirtz, JJJM | 1 |
| Alouffi, S; Khan, MWA | 1 |
| Chen, X; Lai, Y; Lei, C; Liang, Z; Yang, Y; Yang, Z; Zeng, Y | 1 |
| Ahmad, K; Choi, I; Lee, EJ; Lee, YH; Shaikh, S | 1 |
| Arena, E; Brighina, S; Fallico, B; Palmeri, R; Restuccia, C | 1 |
| Dong, L; Wang, JP; Wang, S; Wang, SJ; Zhuang, Y | 1 |
| Ahmad, S; Farooqui, A; Husain, A; Khanam, A; Rehman, S; Yusuf, MA | 1 |
| Cheng, Y; Guo, Y; Xie, Y; Yao, W; Yu, H; Zhong, Q | 1 |
| Auditore, A; Becker, AK; Fleming, T; Messlinger, K; Pischetsrieder, M; Reeh, PW; Sauer, SK | 1 |
| Akhter, A; Kausar, MA; Saeed, M; Siddiqui, AJ; Singh, R | 1 |
| Cai, J; Huang, F; Jiang, G; Liang, G; Song, X; Xu, H; Yin, M; Zhang, L; Zhou, L | 1 |
| Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ | 1 |
| Furuhashi, T; Odani, H; Ogawa, T; Tanaka, T; Yoshioka, S | 1 |
| Carrocera-Pumarino, R; Cepas, V; Collino, M; Collotta, D; Hellwig, M; Henle, T; Manig, F; Mayo, JC; Sainz, RM; Sanmartino, V | 1 |
| Chen, YA; Cheng, KC; Hsieh, CW; Lee, CH; Lin, JA; Tsai, MS; Tu, AT; Wu, JT | 1 |
| Dagnelie, PC; Eussen, SJPM; Maasen, K; Opperhuizen, A; Schalkwijk, CG; Scheijen, JLJM; Stehouwer, CDA; van der Kallen, CJH; van Greevenbroek, MMJ | 1 |
| Grune, T; Herpich, C; Kochlik, B; Norman, K; Ott, C; Raupbach, J; Weber, D | 1 |
16 review(s) available for 3-deoxyglucosone and deoxyglucose
| Article | Year |
|---|---|
Beta2-Microglobulin dialysis amyloid and its formation: role of 3-deoxyglucosone and advanced glycation end products.
Topics: Amyloidosis; beta 2-Microglobulin; Deoxyglucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Renal Dialysis | 1997 |
[Oxidative stress and diabetes mellitus: a possible role of alpha-dicarbonyl compounds in free radical formation].
Topics: Animals; Cattle; Deoxyglucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glycosylation; Humans; Ketoses; Oxidative Stress; Rats; Reactive Oxygen Species | 1997 |
3-deoxyglucosone and AGEs in uremic complications: inactivation of glutathione peroxidase by 3-deoxyglucosone.
Topics: Amyloidosis; Animals; Apoptosis; Arteriosclerosis; Cell Division; Deoxyglucose; Epidermal Growth Factor; Erythrocytes; Glucose; Glutathione Peroxidase; Glutathione Reductase; Glycation End Products, Advanced; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Oxidative Stress; Uremia | 2001 |
Metformin inhibition of glycation processes.
Topics: Azepines; Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Metformin; Pyruvaldehyde; Randomized Controlled Trials as Topic | 2003 |
Modulation of in vivo 3-deoxyglucosone levels.
Topics: Animals; Deoxyglucose; Diet; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Inbred F344; Rats, Sprague-Dawley | 2003 |
[Role of hyperglycemia in the development of diabetic microangiopathy].
Topics: Animals; Apoptosis; Deoxyglucose; Diabetic Angiopathies; Fructose; Glucose; Glycation End Products, Advanced; Hexosamines; Humans; Hyperglycemia; Mitogen-Activated Protein Kinases; Polymers; Postprandial Period; Protein Kinase C; Signal Transduction | 2005 |
3,4-DGE is important for side effects in peritoneal dialysis what about its role in diabetes.
Topics: Apoptosis; Bacterial Infections; Deoxyglucose; Diabetes Mellitus; Glucose; Humans; Peritoneal Dialysis | 2006 |
Chemical and physiological relevance of glucose degradation products in peritoneal dialysis.
Topics: Deoxyglucose; Dialysis Solutions; Galactose; Glucose; Glyoxal; Hot Temperature; Humans; Ketoses; Peritoneal Dialysis; Pyrones; Structure-Activity Relationship | 2012 |
Assay of methylglyoxal and glyoxal and control of peroxidase interference.
Topics: Animals; Deoxyglucose; Glyoxal; Humans; Models, Biological; Peroxidase; Pyruvaldehyde | 2014 |
Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease.
Topics: Aging; Aldehydes; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus; Glyoxal; Humans; Inflammation; Kidney Diseases; Models, Biological; Oxidative Stress; Pyruvaldehyde; Stress, Physiological | 2015 |
Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness.
Topics: Biomarkers; Comorbidity; Critical Care; Critical Illness; Deoxyglucose; Glyoxal; Humans; Hypoxia; Inflammation; Multiple Organ Failure; Pyruvaldehyde; Stress, Physiological | 2017 |
Food-derived 1,2-dicarbonyl compounds and their role in diseases.
Topics: Carbohydrates; Deoxyglucose; Dietary Exposure; Food; Galactose; Glyoxal; Humans; Ketoses; Oxidation-Reduction; Oxidative Stress | 2018 |
Dicarbonyls Generation, Toxicities, Detoxifications and Potential Roles in Diabetes Complications.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Consequences of Dicarbonyl Stress on Skeletal Muscle Proteins in Type 2 Diabetes.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Extracellular Matrix Proteins; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Muscle, Skeletal; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Glycation and Antioxidants: Hand in the Glove of Antiglycation and Natural Antioxidants.
Topics: Antigens, Neoplasm; Antioxidants; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lactoylglutathione Lyase; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappa B; Oxidative Stress; Plant Extracts; Polyphenols; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
The Role of Glyoxalase in Glycation and Carbonyl Stress Induced Metabolic Disorders.
Topics: Aging; Deoxyglucose; Diabetes Mellitus; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Isoenzymes; Lactoylglutathione Lyase; Metabolic Diseases; Neurodegenerative Diseases; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Schiff Bases; Signal Transduction | 2020 |
7 trial(s) available for 3-deoxyglucosone and deoxyglucose
| Article | Year |
|---|---|
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome | 1999 |
Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids.
Topics: Aged; Amino Acids; Arginine; Deoxyglucose; Dialysis Solutions; Female; Filtration; Glucans; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Icodextrin; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Pyruvaldehyde; Sterilization; Time Factors | 2000 |
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia.
Topics: Adolescent; Adult; Aged; Biomarkers; Blood Glucose; Cross-Over Studies; Deoxyglucose; Diabetes Mellitus, Type 1; Double-Blind Method; Drug Administration Schedule; Glycation End Products, Advanced; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Lispro; Middle Aged; Postprandial Period; Pyruvaldehyde; Regression Analysis | 2001 |
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation?
Topics: Adult; Ascitic Fluid; CA-125 Antigen; Cross-Over Studies; Deoxyglucose; Female; Fluorescence; Glucose; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Norleucine; Oxidative Stress; Peritoneal Dialysis; Prospective Studies; Pyrroles; Pyruvaldehyde | 2003 |
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes.
Topics: Carbamates; Confidence Intervals; Deoxyglucose; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Piperidines | 2011 |
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis | 2019 |
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Glyoxal; Humans; Irbesartan; Male; Middle Aged; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors; Treatment Outcome | 2021 |
146 other study(ies) available for 3-deoxyglucosone and deoxyglucose
| Article | Year |
|---|---|
Detection of 3-deoxyfructose and 3-deoxyglucosone in human urine and plasma: evidence for intermediate stages of the Maillard reaction in vivo.
Topics: Borohydrides; Deoxyglucose; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Ketoses; Maillard Reaction; Molecular Structure; Oxidation-Reduction; Proteins | 1992 |
Aldehyde reductase is a major protein associated with 3-deoxyglucosone reductase activity in rat, pig and human livers.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Animals; Deoxyglucose; Humans; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Swine | 1991 |
Effects of 3-deoxyglucosone on the Maillard reaction.
Topics: Collagen; Deoxy Sugars; Deoxyglucose; Glucose; Glycosylation; Guanidines; Maillard Reaction; Microbial Collagenase; Muramidase; Polymers; Serum Albumin, Bovine; Spectrometry, Fluorescence | 1990 |
Identification of fructose 3-phosphate in the lens of diabetic rats.
Topics: Animals; Cross-Linking Reagents; Deoxyglucose; Diabetes Mellitus, Experimental; Fructose-Bisphosphate Aldolase; Fructosephosphates; Glycosylation; Hydrolysis; L-Lactate Dehydrogenase; Lens, Crystalline; Magnetic Resonance Spectroscopy; Rats | 1990 |
Metabolism of 3-deoxyglucosone, an intermediate compound in the Maillard reaction, administered orally or intravenously to rats.
Topics: Absorption; Animals; Blood Glucose; Deoxy Sugars; Deoxyglucose; Intestinal Mucosa; Kidney; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Organ Specificity; Rats; Rats, Inbred Strains; Spleen | 1990 |
Effect of aminoguanidine on the glycation.
Topics: Animals; Cattle; Deoxy Sugars; Deoxyglucose; Fluorescence; Guanidines; Maillard Reaction; Serum Albumin, Bovine | 1989 |
3-Deoxyglucosone, an intermediate product of the Maillard reaction.
Topics: Biopolymers; Carbohydrate Metabolism; Chemical Phenomena; Chemistry; Deoxy Sugars; Deoxyglucose; Fructose; Glucose; Maillard Reaction; Muramidase; Proteins | 1989 |
Metabolism of fructose-3-phosphate in the diabetic rat lens.
Topics: Animals; Carbohydrate Metabolism; Crystallins; Deoxyglucose; Diabetes Mellitus, Experimental; Fructosephosphates; Gas Chromatography-Mass Spectrometry; Glycosylation; Hexosephosphates; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Sprague-Dawley; Sugar Phosphates | 1995 |
Elevated serum levels of 3-deoxyglucosone, a potent protein-cross-linking intermediate of the Maillard reaction, in uremic patients.
Topics: Adult; Aged; Blood Proteins; Cross-Linking Reagents; Deoxyglucose; Diabetic Nephropathies; Female; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Maillard Reaction; Male; Middle Aged; Muramidase; Uremia | 1995 |
In vivo glycation of aldehyde reductase, a major 3-deoxyglucosone reducing enzyme: identification of glycation sites.
Topics: Aldehyde Reductase; Amino Acid Sequence; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Glycosylation; Kidney; Liver; Molecular Sequence Data; Oxidation-Reduction; Peptide Mapping; Protein Processing, Post-Translational; Rats | 1995 |
Quantitation of the glycation intermediate 3-deoxyglucosone by oxidation with rabbit liver oxoaldehyde dehydrogenase to 2-keto-3-deoxygluconic acid followed by high-performance liquid chromatography.
Topics: Aldehyde Oxidoreductases; Animals; Cattle; Chickens; Chromatography, High Pressure Liquid; Deoxyglucose; Gluconates; Guanidines; Hydrogen-Ion Concentration; Liver; N-Acetylneuraminic Acid; Oxidation-Reduction; Rabbits; Rats; Sialic Acids; Spectrometry, Fluorescence; Swine | 1994 |
Chromatographic evidence for pyrraline formation during protein glycation in vitro and in vivo.
Topics: Animals; Blood Proteins; Cattle; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Glucose; Glycosylation; Humans; Magnetic Resonance Spectroscopy; Norleucine; Pyrroles; Serum Albumin, Bovine | 1995 |
Increase in 3-deoxyglucosone levels in diabetic rat plasma. Specific in vivo determination of intermediate in advanced Maillard reaction.
Topics: 2-Naphthylamine; Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Male; Norleucine; Pyrroles; Rats; Rats, Wistar; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet | 1994 |
Reactive Maillard intermediates leading to coloured products-5-hydroxymethyl- and 5-(1,2-dihydroxyethyl)-3(2H)-furanone.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Color; Deoxyglucose; Furans; Gas Chromatography-Mass Spectrometry; Maillard Reaction; Phenylalanine; Spectrum Analysis; Xylose | 1993 |
Monkey 3-deoxyglucosone reductase: tissue distribution and purification of three multiple forms of the kidney enzyme that are identical with dihydrodiol dehydrogenase, aldehyde reductase, and aldose reductase.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Amino Acid Sequence; Animals; Cross Reactions; Deoxyglucose; Humans; Isoenzymes; Kidney; Macaca; Molecular Sequence Data; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Peptide Fragments; Rabbits; Rats; Sequence Analysis; Sequence Homology, Amino Acid; Substrate Specificity; Swine; Tissue Distribution | 1993 |
The presence of a glucose-derived Maillard reaction product in the human lens.
Topics: Animals; Cataract; Cattle; Crystallins; Deoxyglucose; Diabetes Mellitus; Humans; Lens, Crystalline; Maillard Reaction; Norleucine; Protein Conformation; Pyrroles | 1996 |
Modification of beta 2m with advanced glycation end products as observed in dialysis-related amyloidosis by 3-DG accumulating in uremic serum.
Topics: Amyloidosis; Antibodies, Monoclonal; beta 2-Microglobulin; Blotting, Western; Deoxyglucose; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Male; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Uremia | 1996 |
Involvement of glycation and oxidative stress in diabetic macroangiopathy.
Topics: Animals; Aorta; Arteriosclerosis; Deoxyglucose; Diabetes Mellitus; Diabetic Angiopathies; DNA Damage; Epidermal Growth Factor; Gene Expression; Glycation End Products, Advanced; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Oxidation-Reduction; Oxidative Stress; Platelet-Derived Growth Factor; Rats; RNA, Messenger | 1996 |
Induction of apoptotic cell death by methylglyoxal and 3-deoxyglucosone in macrophage-derived cell lines.
Topics: Apoptosis; Cell Line; Cell Nucleus; Deoxyglucose; DNA, Neoplasm; Flow Cytometry; Glutathione; HL-60 Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Macrophages; Oxidants; Pyruvaldehyde; Tumor Cells, Cultured | 1996 |
3-Deoxyglucosone reductase in dog adrenal glands. Identification as aldose reductase.
Topics: Adrenal Glands; Alcohol Oxidoreductases; Aldehyde Reductase; Amino Acid Sequence; Animals; Deoxyglucose; Dogs; Male; Molecular Sequence Data; Sequence Homology, Amino Acid; Substrate Specificity | 1995 |
Serum levels of 3-deoxyglucosone and tissue contents of advanced glycation end products are increased in streptozotocin-induced diabetic rats with nephropathy.
Topics: Animals; Antibodies, Monoclonal; Body Weight; Creatinine; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Kidney; Male; Proteinuria; Rats; Rats, Wistar; Urea | 1996 |
Role of polyol pathway in nonenzymatic glycation.
Topics: Aldehyde Reductase; Animals; Cattle; Deoxyglucose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Erythrocytes; Fructosephosphates; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Polymers; Rhodanine; Serum Albumin, Bovine; Thiazolidines | 1996 |
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes.
Topics: Acrolein; Aldehydes; Amino Acids; Deoxyglucose; Enzyme Activation; Glutathione Reductase; Ketoses; Pyruvaldehyde; Spectrometry, Fluorescence | 1997 |
Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes.
Topics: Animals; Antibodies, Monoclonal; Arginine; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Imidazoles; Kidney; Kinetics; Maillard Reaction; Male; Mice; Rats; Rats, Wistar | 1997 |
Quantitation of 3-deoxyglucosone levels in human plasma.
Topics: 2-Naphthylamine; Adult; Carbon Isotopes; Deoxyglucose; Diabetes Mellitus, Type 1; Ethanol; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Molecular Structure; Reference Values; Sensitivity and Specificity; Trimethylsilyl Compounds; Ultrafiltration | 1997 |
Selective induction of heparin-binding epidermal growth factor-like growth factor by methylglyoxal and 3-deoxyglucosone in rat aortic smooth muscle cells. The involvement of reactive oxygen species formation and a possible implication for atherogenesis in
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Arteriosclerosis; Cell Nucleus; Cells, Cultured; Cycloheximide; Dactinomycin; Deoxyglucose; Diabetic Angiopathies; Epidermal Growth Factor; Gene Expression; Guanidines; Heparin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Kinetics; Muscle, Smooth, Vascular; Peroxides; Pyruvaldehyde; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic | 1997 |
Determination of advanced glycation end products in serum by fluorescence spectroscopy and competitive ELISA.
Topics: Aged; Antibodies, Monoclonal; Arginine; Binding, Competitive; Chromatography, Gel; Deoxyglucose; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hemocyanins; Hemoglobins; Humans; Imidazoles; Molecular Weight; Renal Dialysis; Spectrometry, Fluorescence; Statistics as Topic | 1997 |
Fructose-3-phosphate production and polyol pathway metabolism in diabetic rat hearts.
Topics: Administration, Oral; Ampholyte Mixtures; Animals; Chromatography, High Pressure Liquid; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Fructosephosphates; Gas Chromatography-Mass Spectrometry; Glucose; Imidazoles; Imidazolidines; Lens, Crystalline; Magnetic Resonance Spectroscopy; Male; Myocardium; Perchlorates; Phosphorus Isotopes; Polymers; Rats; Rats, Sprague-Dawley; Sorbitol | 1997 |
Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucosone.
Topics: Aldehyde Reductase; Animals; Apoptosis; Blotting, Northern; Cell Survival; Deoxyglucose; Enzyme Activation; Flow Cytometry; Immunoblotting; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection | 1998 |
Accelerated formation of N epsilon-(carboxymethyl) lysine, an advanced glycation end product, by glyoxal and 3-deoxyglucosone in cultured rat sensory neurons.
Topics: Animals; Apoptosis; Culture Techniques; Deoxyglucose; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycation End Products, Advanced; Glyoxal; Guanidines; Lysine; Neurons, Afferent; Rats; Rats, Sprague-Dawley | 1998 |
Characterization of a blue fluorophore isolated from in vitro reaction of N-proportional to-acetyllysine and 3-deoxyglucosone.
Topics: Adult; Aged; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyglucose; Eye Proteins; Fluorescent Dyes; Hemoglobins; Humans; Lysine; Magnetic Resonance Spectroscopy; Middle Aged; Spectrometry, Fluorescence; Spectrometry, Mass, Fast Atom Bombardment | 1998 |
Teratogenicity of 3-deoxyglucosone and diabetic embryopathy.
Topics: Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glucose; Glyoxal; Hyperglycemia; Male; Pregnancy; Pyruvaldehyde; Rats; Teratogens | 1998 |
Immunohistochemical detection of imidazolone and N(epsilon)-(carboxymethyl)lysine in aortas of hemodialysis patients.
Topics: Aged; Aorta; Arginine; Arteriosclerosis; Deoxyglucose; Female; Glyoxal; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyruvaldehyde; Renal Dialysis; Uremia | 1998 |
Characterisation of a novel AGE-compound derived from lysine and 3-deoxyglucosone.
Topics: Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyglucose; Glycation End Products, Advanced; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Molecular Structure; Spectrometry, Mass, Fast Atom Bombardment | 1998 |
Accumulation of carbonyls accelerates the formation of pentosidine, an advanced glycation end product: carbonyl stress in uremia.
Topics: Aged; Aldehydes; Arginine; Carboxylic Acids; Deoxyglucose; Depression, Chemical; Esters; Glycosylation; Guanidines; Humans; Ketones; Lysine; Maillard Reaction; Male; Middle Aged; Molecular Weight; Phenylhydrazines; Renal Dialysis; Thiadiazoles; Thiazolidines; Ultrafiltration; Uremia | 1998 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
The cytotoxicity of methylglyoxal and 3-deoxyglucosone is decreased in the aldehyde reductase gene-transfected cells.
Topics: Aldehyde Reductase; Animals; Deoxyglucose; Flow Cytometry; Gene Expression; Glucose; Intracellular Fluid; PC12 Cells; Pyruvaldehyde; Rats; Reactive Oxygen Species; Transfection | 1999 |
Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Synergism; Free Radical Scavengers; Glycation End Products, Advanced; Glycosylation; Neurodegenerative Diseases; Neurons; Oxidative Stress; Peroxides; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 1999 |
Accumulation of alpha-oxoaldehydes during oxidative stress: a role in cytotoxicity.
Topics: Animals; Cell Line; Cell Survival; Deoxyglucose; Dinitrochlorobenzene; Glutathione; Glyoxal; Guanidines; Hydrogen Peroxide; Macrophages; Mice; Necrosis; Nitroarginine; Oxidative Stress; Pyruvaldehyde | 1999 |
Gas chromatographic-mass spectrometric analysis of erythrocyte 3-deoxyglucosone in hemodialysis patients.
Topics: Aged; Case-Control Studies; Deoxyglucose; Erythrocytes; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Renal Dialysis | 1999 |
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose.
Topics: Deoxyglucose; Fructosamine; Glucose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; In Vitro Techniques; Lysine; Proteins; Pyruvaldehyde; Schiff Bases; Serum Albumin | 1999 |
Modification of beta 2-microglobulin with D-glucose or 3-deoxyglucosone inhibits A beta 2M amyloid fibril extension in vitro.
Topics: Amyloid; Amyloidosis; Benzothiazoles; beta 2-Microglobulin; Blotting, Western; Deoxyglucose; Glucose; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kinetics; Male; Middle Aged; Popliteal Cyst; Spectrometry, Fluorescence; Thiazoles | 1999 |
Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Glutathione; Glycation End Products, Advanced; Guanidines; Motor Neurons; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Spinal Cord | 2000 |
Kinetics and mechanism of the reaction of aminoguanidine with the alpha-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions.
Topics: Deoxyglucose; Enzyme Inhibitors; Glyoxal; Guanidines; Kinetics; Pyruvaldehyde; Spectrophotometry; Triazines | 2000 |
Mechanism of the inhibitory effect of OPB-9195 [(+/-)-2-isopropylidenehydrazono-4-oxo-thiazolidin-5-yla cetanilide] on advanced glycation end product and advanced lipoxidation end product formation.
Topics: Aldehydes; Arachidonic Acid; Arginine; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Glyoxal; Guanidines; Lipid Metabolism; Lysine; Malondialdehyde; Oxidation-Reduction; Peritoneal Dialysis; Prodrugs; Pyruvaldehyde; Thiadiazoles; Thiazolidines | 2000 |
Formation of a phospholipid-linked pyrrolecarbaldehyde from model reactions of D-glucose and 3-deoxyglucosone with phosphatidyl ethanolamine.
Topics: Aldehydes; Deoxyglucose; Gas Chromatography-Mass Spectrometry; Glucose; Magnetic Resonance Spectroscopy; Phosphatidylethanolamines; Proline | 2000 |
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines | 2000 |
Evidence for non-enzymatic glycosylation in Escherichia coli.
Topics: Bacterial Proteins; Deoxyglucose; Dimerization; Escherichia coli; Fluorescence; Glycosylation; Humans; Imidazoles; Interferon-gamma; Lysine; Protein Processing, Post-Translational; Recombinant Proteins; Spectrometry, Fluorescence | 2001 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses | 2001 |
Sodium sulfite and N-acetylcysteine: new additives to dialysate for inhibiting formation of glucose degradation products and advanced glycation end-products.
Topics: Acetylcysteine; Collagen Type IV; Deoxyglucose; Dialysis Solutions; Fluorescence; Glucose; Glycation End Products, Advanced; Glyoxylates; Humans; In Vitro Techniques; Pyruvaldehyde; Serum Albumin; Sulfites | 2001 |
Immunological detection of a novel advanced glycation end-product.
Topics: Animals; Deoxyglucose; Glycation End Products, Advanced; Humans; Immunoassay; Protein Processing, Post-Translational; Rabbits | 2001 |
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping.
Topics: Deoxyglucose; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Glucose; Glycoproteins; Glycosylation; Lysine; Maillard Reaction; Muramidase; Peptide Mapping; Pyruvaldehyde; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 2002 |
DYN 12, a small molecule inhibitor of the enzyme amadorase, lowers plasma 3-deoxyglucosone levels in diabetic rats.
Topics: Amino Acid Oxidoreductases; Animals; Deoxyglucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Kidney Glomerulus; Organic Chemicals; Phosphotransferases (Alcohol Group Acceptor); Rats; Reference Values | 2001 |
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid.
Topics: Animals; CHO Cells; Cricetinae; Deoxyglucose; Dialysis Solutions; Gene Expression Regulation, Enzymologic; Glucose; Glutathione; Guanidines; Humans; In Vitro Techniques; Kidney Failure, Chronic; Lactoylglutathione Lyase; Membranes, Artificial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde; Yeasts | 2002 |
Gas chromatographic-mass spectrometric determination of erythrocyte 3-deoxyglucosone in diabetic patients.
Topics: Adolescent; Adult; Case-Control Studies; Child; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocytes; Female; Gas Chromatography-Mass Spectrometry; Glycated Hemoglobin; Humans; Male; Reference Standards | 2002 |
Plasma 3-deoxyglucosone elevation in chronic renal failure is associated with increased aldose reductase in erythrocytes.
Topics: Adult; Aldehyde Reductase; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Erythrocytes; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Osmolar Concentration; Uremia | 2002 |
Oxidative deamination of benzylamine by glycoxidation.
Topics: Benzaldehydes; Benzylamines; Chelating Agents; Copper; Deamination; Deoxyglucose; Edetic Acid; Free Radical Scavengers; Glucose; Glucose Oxidase; Hydrogen-Ion Concentration; Hydroxyl Radical; Kinetics; Metals; Nitrogen; Oxidation-Reduction; Oxygen; Pyruvaldehyde; Reactive Oxygen Species | 2003 |
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Deoxyglucose; Erythrocytes; Glutathione; Glutathione Peroxidase; Glyoxal; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Muscle, Smooth; Oxidative Stress; Peptides; Phenylglyoxal; Protein Binding; Pyruvaldehyde; Rats; Selenocysteine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2003 |
Relation between serum 3-deoxyglucosone and development of diabetic microangiopathy.
Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Fasting; Glycated Hemoglobin; Glycosylation; Humans; Middle Aged; Platelet Activating Factor; Reference Values | 2003 |
Diabetic ketoacidosis and its treatment increase plasma 3-deoxyglucosone.
Topics: Adolescent; Adult; Blood Glucose; Child; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Electrolytes; Humans; Hydrogen-Ion Concentration; Time Factors | 2003 |
Oxidative DNA damage by hyperglycemia-related aldehydes and its marked enhancement by hydrogen peroxide.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Copper; Deoxyglucose; Deoxyguanosine; Diabetes Complications; DNA Damage; Drug Synergism; Glyceraldehyde; HL-60 Cells; Humans; Hydrogen Peroxide; Hyperglycemia; Neoplasms; Oxidation-Reduction | 2003 |
Suppression of 3-deoxyglucosone and heparin-binding epidermal growth factor-like growth factor mRNA expression by an aldose reductase inhibitor in rat vascular smooth muscle cells.
Topics: Aldehyde Reductase; Animals; Blotting, Northern; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Epidermal Growth Factor; Glucose; Glycation End Products, Advanced; Heparin-binding EGF-like Growth Factor; Imidazoles; Imidazolidines; Intercellular Signaling Peptides and Proteins; Mitogens; Muscle, Smooth, Vascular; Oxidative Stress; Rats; RNA, Messenger; Sorbitol; Thiobarbituric Acid Reactive Substances; Thymidine | 2004 |
A novel enzymatic reaction for converting DNA to CO-DNA.
Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chromatography, Gel; Deoxyglucose; Deoxyribose; DNA; Electrophoresis, Polyacrylamide Gel; Enzymes; Glucose; Molecular Structure; Myocardium; Telencephalon | 2004 |
Immunochemical detection of 3-deoxyglucosone in serum.
Topics: Animals; Biomarkers; Blood Chemical Analysis; Deoxyglucose; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Immunoenzyme Techniques; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Streptozocin | 2004 |
Pyridoxal phosphate and hepatocyte growth factor prevent dialysate-induced peritoneal damage.
Topics: Animals; Deoxyglucose; Dialysis Solutions; Glycation End Products, Advanced; Hepatocyte Growth Factor; Male; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Peritonitis; Pyridoxal Phosphate; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2005 |
Nepsilon-(Carboxymethyl)lysine and 3-DG-imidazolone are major AGE structures in protein modification by 3-deoxyglucosone.
Topics: Adult; Aged; Antibodies, Monoclonal; Aorta; Arginine; Arteriosclerosis; Binding, Competitive; Chromatography; Chromatography, High Pressure Liquid; Cytoplasm; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Foam Cells; Glycation End Products, Advanced; Humans; Imidazoles; Immunochemistry; Immunohistochemistry; Lysine; Male; Middle Aged; Models, Biological; Models, Chemical; Norleucine; Pyrroles; Temperature; Time Factors | 2004 |
Fate of the glucose degradation products 3-deoxyglucosone and glyoxal during peritoneal dialysis.
Topics: Absorption; Chromatography, High Pressure Liquid; Deoxyglucose; Dialysis Solutions; Epithelial Cells; Fibroblasts; Glycation End Products, Advanced; Glyoxal; Humans; Imidazoles; Kinetics; Peritoneal Dialysis; Peritoneum; Time Factors | 2005 |
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence | 2005 |
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
Topics: Adolescent; Adult; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Susceptibility; Glycated Hemoglobin; Humans; Indians, North American; Oxidative Stress; Pyruvaldehyde; Risk Factors | 2005 |
The internalization and metabolism of 3-deoxyglucosone in human umbilical vein endothelial cells.
Topics: Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Muscle, Smooth, Vascular; Time Factors; Tritium; Umbilical Veins | 2006 |
Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1).
Topics: Adult; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Oxidoreductases; Amino Acid Sequence; Animals; Cell Line; Deoxyglucose; Erythrocytes; Gene Expression Regulation, Enzymologic; Gluconates; Humans; Hydrogen-Ion Concentration; Liver; Lung; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Middle Aged; Molecular Sequence Data; Molecular Weight; Retinal Dehydrogenase; Retinaldehyde; RNA, Messenger; Substrate Specificity; Testis | 2007 |
Reducing the formation of glucose degradation products in peritoneal dialysis solutions by ultrahigh temperature ohmic heating.
Topics: Deoxyglucose; Dialysis Solutions; Glucose; Glyoxal; Hot Temperature; Peritoneal Dialysis; Pyruvaldehyde | 2007 |
Identification and determination of alpha-dicarbonyl compounds formed in the degradation of sugars.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Fructose; Glucose; Glycation End Products, Advanced; Glyoxal; Ketoses; Maillard Reaction; Models, Chemical; Molecular Structure | 2007 |
Formation of alpha-dicarbonyl compounds in beer during storage of Pilsner.
Topics: Acetaldehyde; Aldehydes; Beer; Chromatography, Gas; Deoxyglucose; Food Handling; Food Preservation; Furans; Humans; Smell; Time Factors | 2008 |
A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry.
Topics: Calibration; Deoxyglucose; Gas Chromatography-Mass Spectrometry; Glyoxal; Humans; Pyruvaldehyde | 2008 |
Metformin restores impaired HDL-mediated cholesterol efflux due to glycation.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cells, Cultured; Cholesterol; Deoxyglucose; Gene Expression; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lipoproteins, HDL; Macrophages; Metformin | 2009 |
Degradation of glucose: reinvestigation of reactive alpha-Dicarbonyl compounds.
Topics: Deoxyglucose; Glucose; Glyoxal; Ketoses; Lysine; Maillard Reaction; Pentanes; Phenylenediamines; Quinoxalines | 2009 |
Two dicarbonyl compounds, 3-deoxyglucosone and methylglyoxal, differentially modulate dermal fibroblasts.
Topics: Cell Line; Collagen; Deoxyglucose; Extracellular Matrix; Fibroblasts; Glycation End Products, Advanced; Humans; Integrin beta1; Protein Isoforms; Pyruvaldehyde; Skin; Transforming Growth Factor beta1 | 2010 |
Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10).
Topics: Aldehyde Reductase; Aldehydes; Aldo-Keto Reductases; Animals; Brain; Brain Chemistry; Cloning, Molecular; Deoxyglucose; DNA, Complementary; Female; Genes; Humans; Kinetics; Male; NADP; Oxidative Stress; Rats; Recombinant Proteins; Substrate Specificity; Tissue Distribution | 2010 |
3-deoxygalactosone, a "new" 1,2-dicarbonyl compound in milk products.
Topics: Animals; Deoxyglucose; Food Analysis; Galactose; Maillard Reaction; Milk; Quinoxalines; Spectrometry, Mass, Electrospray Ionization | 2010 |
Effect of antibrowning agents on browning and intermediate formation in the glucose-glutamic acid model.
Topics: Citric Acid; Condiments; Deoxyglucose; Ferrous Compounds; Food Handling; Food Preservatives; Furaldehyde; Glucose; Glutamic Acid; Maillard Reaction; Models, Chemical; Osmolar Concentration; Oxalic Acid; Oxygen; Soy Foods; Temperature; Time Factors | 2010 |
Modification of collagen by 3-deoxyglucosone alters wound healing through differential regulation of p38 MAP kinase.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blotting, Western; Caspase 3; Cell Proliferation; Cells, Cultured; Child; Child, Preschool; Collagen; Deoxyglucose; Fluorescent Antibody Technique; Humans; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pseudopodia; Reverse Transcriptase Polymerase Chain Reaction; Wound Healing; Young Adult | 2011 |
Correlating changes that occur in chemical properties with the generation of antioxidant capacity in different sugar-amino acid Maillard reaction models.
Topics: Amino Acids; Antioxidants; Color; Deoxy Sugars; Deoxyglucose; Fructose; Glucose; Glycine; Hot Temperature; Hydrogen-Ion Concentration; Ketoses; Kinetics; Lysine; Maillard Reaction; Models, Chemical; Pentoses; Ribose; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2011 |
3-Deoxy-glucosone is an intermediate in the formation of furfurals from D-glucose.
Topics: Deoxyglucose; Furaldehyde; Glucose; Thermodynamics | 2011 |
Rearrangement of 3-deoxy-D-erythro-hexos-2-ulose in aqueous solution: NMR evidence of intramolecular 1,2-hydrogen transfer.
Topics: Buffers; Chemistry, Pharmaceutical; Deoxyglucose; Drug Stability; Hexuronic Acids; Hydrogen; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Molecular Conformation; Oxygen; Solutions; Staining and Labeling; Stereoisomerism; Water | 2011 |
Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry.
Topics: Adult; Aged; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Female; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Humans; Limit of Detection; Male; Middle Aged; Nails; Phenylenediamines; Pyruvaldehyde; Reproducibility of Results; Signal-To-Noise Ratio; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Survey of 1,2-dicarbonyl compounds in commercial honey of different floral origin.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Food Analysis; Furaldehyde; Glyoxal; Honey; Ketones; Limit of Detection; Phenols; Pyruvaldehyde | 2011 |
1,2-dicarbonyl compounds in commonly consumed foods.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Diet; Food Analysis; Furaldehyde; Galactose; Pyruvaldehyde | 2012 |
Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen.
Topics: Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glyoxal; Humans; Isotope Labeling; Perchlorates; Phenylenediamines; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors | 2014 |
Response surface methodology as optimization strategy for reduction of reactive carbonyl species in foods by means of phenolic chemistry.
Topics: Animals; Cattle; Cooking; Deoxyglucose; Food Additives; Food Preservation; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Milk; Phenols; Pyruvaldehyde | 2013 |
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling | 2013 |
Two α-dicarbonyls downregulate migration, invasion, and adhesion of liver cancer cells in a p53-dependent manner.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Deoxyglucose; Down-Regulation; Drug Therapy, Combination; Genes, p53; Humans; Liver Neoplasms; Neoplasm Invasiveness; Pyruvaldehyde | 2013 |
Dietary influence on urinary excretion of 3-deoxyglucosone and its metabolite 3-deoxyfructose.
Topics: Adult; Deoxyglucose; Diet; Digestion; Female; Honey; Humans; Ketoses; Male; Young Adult | 2014 |
Free α-dicarbonyl compounds in coffee, barley coffee and soy sauce and effects of in vitro digestion.
Topics: Chromatography, High Pressure Liquid; Coffea; Coffee; Cooking; Deoxyglucose; Diacetyl; Digestion; Glyoxal; Hordeum; Hot Temperature; Humans; Models, Biological; Pyruvaldehyde; Soy Foods | 2014 |
Structure- and concentration-specific assessment of the physiological reactivity of α-dicarbonyl glucose degradation products in peritoneal dialysis fluids.
Topics: Animals; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyglucose; Dialysis Solutions; Galactose; Glucose; Glycation End Products, Advanced; Glyoxal; Ketoses; Mice; NIH 3T3 Cells; Peptides; Peritoneal Dialysis; Pyrones; Pyruvaldehyde; Ribonuclease, Pancreatic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Investigation of α-dicarbonyl compounds in baby foods by high-performance liquid chromatography coupled with electrospray ionization mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Deoxyglucose; Furaldehyde; Glyoxal; Humans; Infant Food; Infant Formula; Ketoses; Pyruvaldehyde; Spectrometry, Mass, Electrospray Ionization | 2014 |
Identification and determination of 3-deoxyglucosone and glucosone in carbohydrate-rich foods.
Topics: Coffee; Deoxyglucose; Food Analysis; Fructose; Gas Chromatography-Mass Spectrometry; Honey; Humans; Ketoses; Maillard Reaction | 2015 |
Physicochemical analysis of structural alteration and advanced glycation end products generation during glycation of H2A histone by 3-deoxyglucosone.
Topics: Arginine; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyglucose; Fluorescence; Glycation End Products, Advanced; Glycosylation; Histones; Humans; Lysine; Spectroscopy, Fourier Transform Infrared | 2014 |
3-Deoxyglucosone: a potential glycating agent accountable for structural alteration in H3 histone protein through generation of different AGEs.
Topics: Animals; Cattle; Deoxyglucose; Diabetes Complications; Glycation End Products, Advanced; Glycosylation; Histones | 2015 |
Post-Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study.
Topics: Atherosclerosis; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glyoxal; Humans; Hyperglycemia; Male; Mass Spectrometry; Middle Aged; Postprandial Period; Pyruvaldehyde | 2015 |
Protein-bound uraemic toxins, dicarbonyl stress and advanced glycation end products in conventional and extended haemodialysis and haemodiafiltration.
Topics: Blood Proteins; Deoxyglucose; Female; Glycation End Products, Advanced; Hemodiafiltration; Humans; Male; Middle Aged; Oxidative Stress; Renal Dialysis; Toxins, Biological; Uremia | 2015 |
Association between Advanced Glycation End Products and Impaired Fasting Glucose: Results from the SALIA Study.
Topics: Aged; Biomarkers; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Fasting; Female; Glucose; Glycation End Products, Advanced; Humans; Inflammation; Insulin; Insulin Resistance; Pilot Projects; Prediabetic State; Tandem Mass Spectrometry | 2015 |
Glycation of H1 Histone by 3-Deoxyglucosone: Effects on Protein Structure and Generation of Different Advanced Glycation End Products.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyglucose; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Histones; Protein Denaturation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Temperature | 2015 |
3-Deoxyglucosone Induced Acute Glucose Intolerance in Sprague-Dawley Rats: Involvement of Insulin Resistance and Impaired β-cell Function.
Topics: Animals; Deoxyglucose; Glucose Intolerance; Insulin Resistance; Insulin-Secreting Cells; Rats; Rats, Sprague-Dawley | 2016 |
DNA Glycation from 3-Deoxyglucosone Leads to the Formation of AGEs: Potential Role in Cancer Auto-antibodies.
Topics: Animals; Antibodies, Neoplasm; Autoantibodies; Case-Control Studies; Deoxyglucose; DNA, Neoplasm; Female; Glycation End Products, Advanced; Humans; Neoplasms; Rabbits | 2016 |
Investigations on the reactions of α-dicarbonyl compounds with amino acids and proteins during in vitro digestion of biscuits.
Topics: Amino Acids; Cysteine; Deoxyglucose; Dietary Proteins; Digestion; Lysine; Mass Spectrometry; Models, Biological; Ovalbumin; Pyruvaldehyde | 2016 |
Occurrence of (Z)-3,4-Dideoxyglucoson-3-ene in Different Types of Beer and Malt Beer as a Result of 3-Deoxyhexosone Interconversion.
Topics: Beer; Chromatography, High Pressure Liquid; Deoxyglucose; Furaldehyde; Galactose; Stereoisomerism; Tandem Mass Spectrometry; Triticum | 2016 |
3-Deoxyglucosone induces insulin resistance by impairing insulin signaling in HepG2 cells.
Topics: Animals; Cell Survival; Deoxyglucose; Female; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Male; Mice; Middle Aged; Signal Transduction | 2016 |
Intra-molecular lysine-arginine derived advanced glycation end-product cross-linking in Type I collagen: A molecular dynamics simulation study.
Topics: Animals; Arginine; Binding Sites; Collagen Type I; Cross-Linking Reagents; Deoxyglucose; Glycation End Products, Advanced; Imidazoles; Lysine; Models, Molecular; Molecular Dynamics Simulation; Rats | 2016 |
Acute Reduction of Incretin Effect and Glucose Intolerance in Rats by Single Intragastric Administration of 3-deoxyglucosone.
Topics: Animals; Cyclic AMP; Deoxyglucose; Glucagon; Glucagon-Like Peptide 1; Glucose Intolerance; Incretins; Insulin; Male; Mice; Prediabetic State; Rats | 2017 |
Effect of hydroxytyrosol and olive leaf extract on 1,2-dicarbonyl compounds, hydroxymethylfurfural and advanced glycation endproducts in a biscuit model.
Topics: Arginine; Chromatography, Liquid; Deoxyglucose; Flour; Food Handling; Furaldehyde; Gallic Acid; Glycation End Products, Advanced; Lysine; Maillard Reaction; Olea; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyruvaldehyde; Quercetin; Tandem Mass Spectrometry; Triticum | 2017 |
Maillard reaction and caramelization during hazelnut roasting: A multiresponse kinetic study.
Topics: Amino Acids; Cooking; Corylus; Deoxyglucose; Fructose; Furaldehyde; Glucose; Glyoxal; Kinetics; Maillard Reaction; Pyruvaldehyde; Sucrose | 2017 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Retinal Detachment | 2017 |
Evaluation of an olive leaf extract as a natural source of antiglycative compounds.
Topics: Chromatography, Liquid; Deoxyglucose; Fructosamine; Galactose; Glycation End Products, Advanced; Glycosylation; Glyoxal; Lysine; Olea; Ornithine; Phenols; Phenylethyl Alcohol; Plant Extracts; Plant Leaves; Pyrimidines; Pyruvaldehyde; Tandem Mass Spectrometry | 2017 |
Inhibitory mechanism of quercetin against the formation of 5-(hydroxymethyl)-2-furaldehyde in buckwheat flour bread by ultra-performance liquid chromatography coupled with high-resolution tandem mass spectrometry.
Topics: Bread; Chromatography, High Pressure Liquid; Deoxyglucose; Fagopyrum; Flour; Furaldehyde; Quercetin; Tandem Mass Spectrometry | 2017 |
A comparison of dicarbonyl stress and advanced glycation endproducts in lifelong endurance athletes vs. sedentary controls.
Topics: Aged; Athletes; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Deoxyglucose; Exercise; Glycation End Products, Advanced; Glyoxal; Humans; Male; Middle Aged; Physical Endurance; Sedentary Behavior; Stress, Physiological; Sugar Alcohol Dehydrogenases; Surveys and Questionnaires | 2017 |
Involvement of exogenous 3‑deoxyglucosone in β‑cell dysfunction induces impaired glucose regulation.
Topics: Animals; Blood Glucose; Cell Line; Deoxyglucose; Fasting; Glucose; Glucose Tolerance Test; Insulin; Insulin-Secreting Cells; Male; Mice; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Liquid Chromatographic Analysis of α-Dicarbonyls Using Girard-T Reagent Derivatives.
Topics: Betaine; Chromatography, Liquid; Deoxyglucose; Furaldehyde; Glyoxal; High Fructose Corn Syrup; Limit of Detection; Linear Models; Reproducibility of Results | 2017 |
Metformin attenuates myocardium dicarbonyl stress induced by chronic hypertriglyceridemia.
Topics: Animals; Deoxyglucose; Diet; Glutathione; Glyoxal; Hypertriglyceridemia; Hypoglycemic Agents; Lactoylglutathione Lyase; Male; Metformin; Myocardium; Pyruvaldehyde; Rats; Rats, Wistar; Stress, Physiological | 2018 |
The downregulation of sweet taste receptor signaling in enteroendocrine L-cells mediates 3-deoxyglucosone-induced attenuation of high glucose-stimulated GLP-1 secretion.
Topics: Animals; Benzene Derivatives; Blotting, Western; Cell Line; Cyclic AMP; Deoxyglucose; Dietary Sugars; Down-Regulation; Enteroendocrine Cells; Enzyme-Linked Immunosorbent Assay; Glucagon-Like Peptide 1; Glucose; Intestinal Secretions; Mice; Osmolar Concentration; Protein Subunits; Receptors, G-Protein-Coupled; Second Messenger Systems; TRPM Cation Channels | 2018 |
Aromatic aldehydes as selective fluorogenic derivatizing agents for α-dicarbonyl compounds. Application to HPLC analysis of some advanced glycation end products and oxidative stress biomarkers in human serum.
Topics: Acetates; Aldehydes; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus; Fluorescence; Glycation End Products, Advanced; Healthy Volunteers; Heart Diseases; Humans; Imidazoles; Ketoses; Limit of Detection; Oxidative Stress; Rheumatic Diseases; Sensitivity and Specificity | 2018 |
Exogenous 3-Deoxyglucosone-Induced Carbonyl and Oxidative Stress Causes β-Cells Dysfunction by Impairing Gut Permeability in Rats.
Topics: Animals; Colon; Deoxyglucose; Gene Expression Regulation; Insulin-Secreting Cells; Permeability; Protein Carbonylation; Rats; Rats, Sprague-Dawley | 2018 |
Elevated levels of α-dicarbonyl compounds in the plasma of type II diabetics and their relevance with diabetic nephropathy.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diacetyl; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde | 2019 |
Identification of [6-Hydroxy-2-(hydroxymethyl)-5-oxo-5,6-dihydro-2 H-pyran-3-yl]-cysteine (HHPC) as a Cysteine-specific Modification Formed from 3,4-Dideoxyglucosone-3-ene (3,4-DGE).
Topics: Chromatography, High Pressure Liquid; Cysteine; Cystine; Deoxyglucose; Dialysis Solutions; Galactose; Glycation End Products, Advanced; Peptides; Pyrans; Pyrones; Tandem Mass Spectrometry | 2019 |
Mitigation of 3-deoxyglucosone and 5-hydroxymethylfurfural in brown fermented milk via an alternative browning process based on the hydrolysis of endogenous lactose.
Topics: Animals; Cattle; Deoxyglucose; Fermentation; Furaldehyde; Glucose; Hot Temperature; Hydrolysis; Lactose; Maillard Reaction; Milk | 2019 |
Mechanisms non-enzymatic browning in orange juice during storage.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Citrus sinensis; Color; Deoxyglucose; Food Storage; Fructose; Fruit and Vegetable Juices; Glyoxal; Maillard Reaction; Mass Spectrometry; Spectrophotometry, Ultraviolet; Temperature | 2019 |
Formation of 3-deoxyglucosone in the malting process.
Topics: Amino Acids; Beer; Chromatography, High Pressure Liquid; Deoxyglucose; Food Handling; Maillard Reaction; Monosaccharides; Phenylenediamines; Spectrophotometry, Ultraviolet; Temperature | 2019 |
Basic Structure of Melanoidins Formed in the Maillard Reaction of 3-Deoxyglucosone and γ-Aminobutyric Acid.
Topics: Amino Acids; Deoxyglucose; gamma-Aminobutyric Acid; Glucose; Kinetics; Maillard Reaction; Molecular Structure; Polymers | 2019 |
Studies on the Formation of 3-Deoxyglucosone- and Methylglyoxal-Derived Hydroimidazolones of Creatine during Heat Treatment of Meat.
Topics: Animals; Arginine; Cattle; Chickens; Chromatography, High Pressure Liquid; Cooking; Creatine; Deoxyglucose; Hot Temperature; Imidazoles; Lysine; Maillard Reaction; Meat; Pyruvaldehyde; Swine; Tandem Mass Spectrometry | 2019 |
Acute exposure to 3‑deoxyglucosone at high glucose levels impairs insulin secretion from β‑cells by downregulating the sweet taste receptor signaling pathway.
Topics: Animals; Benzene Derivatives; Cells, Cultured; Deoxyglucose; Down-Regulation; Glucose; Glucose Transporter Type 2; Insulin Secretion; Insulin-Secreting Cells; Male; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; TRPM Cation Channels | 2019 |
3-Deoxyglucosone interferes with insulin signaling and attenuates insulin action on glucose-induced GLP-1 secretion in the enteroendocrine L cell line STC-1.
Topics: Animals; Cell Line; Deoxyglucose; Enteroendocrine Cells; Glucagon-Like Peptide 1; Glucose; Glucose Transporter Type 2; Insulin; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Signal Transduction | 2019 |
3-Deoxyglucosone reduces glucagon-like peptide-1 secretion at low glucose levels through down-regulation of SGLT1 expression in STC-1 cells.
Topics: Animals; Cells, Cultured; Cyclic AMP; Deoxyglucose; Enteroendocrine Cells; Glucagon-Like Peptide 1; Glucose; Insulin; Intestine, Small; Mice; Sodium-Glucose Transporter 1 | 2021 |
Measurement of α-dicarbonyl compounds in human saliva by pre-column derivatization HPLC.
Topics: Adult; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde; Saliva | 2019 |
Pyrraline Formation Modulated by Sodium Chloride and Controlled by Encapsulation with Different Coating Materials in the Maillard Reaction.
Topics: Amylose; Deoxyglucose; Glucose; Glycation End Products, Advanced; Hot Temperature; Lysine; Maillard Reaction; Norleucine; Pyrroles; Sodium Chloride; Zea mays | 2019 |
Antibacterial activity of 1,2-dicarbonyl compounds and the influence of the in vitro assay system.
Topics: Anti-Bacterial Agents; Bacillus cereus; Deoxyglucose; Glyoxal; Kinetics; Microbial Sensitivity Tests; Pseudomonas fluorescens; Pyruvaldehyde; Salmonella enterica | 2020 |
Formation and migration of α-dicarbonyl compounds during storage and reheating of a sugary food simulation system.
Topics: Carbohydrates; Deoxyglucose; Diacetyl; Food; Food Analysis; Food Storage; Glucose; Glycation End Products, Advanced; Glyoxal; Hot Temperature; Lysine; Pyruvaldehyde; Temperature | 2020 |
Kinetic study on the generation of furosine and pyrraline in a Maillard reaction model system of d-glucose and l-lysine.
Topics: Deoxyglucose; Glucose; Kinetics; Lysine; Maillard Reaction; Norleucine; Pyrroles; Pyruvaldehyde | 2020 |
5-Hydroxymethylfurfural accumulation plays a critical role on acrylamide formation in coffee during roasting as confirmed by multiresponse kinetic modelling.
Topics: Acrylamide; Amino Acids; Coffee; Deoxyglucose; Food-Processing Industry; Furaldehyde; Glucose; Glyoxal; Hot Temperature; Kinetics; Pyruvaldehyde; Sucrose | 2020 |
Reactive dicarbonyl compounds cause Calcitonin Gene-Related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Deoxyglucose; Drug Interactions; Inflammation; Mice; Mice, Inbred C57BL; Nerve Fibers; Peritoneum; Prostaglandins; Pyruvaldehyde; Skin; Temperature | 2020 |
Alteration of Intestinal Microbiota in 3-Deoxyglucosone-Induced Prediabetic Rats.
Topics: Administration, Oral; Animals; Deoxyglucose; Gastrointestinal Microbiome; Glucagon-Like Peptide 2; Glucose Tolerance Test; Lipopolysaccharides; Male; Prediabetic State; Rats, Sprague-Dawley; RNA, Ribosomal, 16S | 2020 |
Increase in the peripheral blood methylglyoxal levels in 10% of hospitalized chronic schizophrenia patients.
Topics: Adult; Biomarkers; Case-Control Studies; Chronic Disease; Deoxyglucose; Female; Glyoxal; Hospitalization; Humans; Male; Middle Aged; Pyruvaldehyde; Schizophrenia; Stress, Physiological | 2021 |
In Vitro Evaluation of the Toxicological Profile and Oxidative Stress of Relevant Diet-Related Advanced Glycation End Products and Related 1,2-Dicarbonyls.
Topics: Apoptosis; Deoxyglucose; Galactose; Glycation End Products, Advanced; Humans; In Vitro Techniques; Inflammation; Keratinocytes; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pyrones; Reactive Oxygen Species | 2021 |
Reduction of 3-Deoxyglucosone by Epigallocatechin Gallate Results Partially from an Addition Reaction: The Possible Mechanism of Decreased 5-Hydroxymethylfurfural in Epigallocatechin Gallate-Treated Black Garlic.
Topics: Catechin; Deoxyglucose; Dose-Response Relationship, Drug; Furaldehyde; Garlic | 2021 |
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
Topics: Aged; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diet; Diet Surveys; Dietary Exposure; Fasting; Female; Glycation End Products, Advanced; Glyoxal; Humans; Linear Models; Male; Mass Spectrometry; Middle Aged; Netherlands; Optical Imaging; Pyruvaldehyde; Skin | 2022 |
Fasting Concentrations and Postprandial Response of 1,2-Dicarbonyl Compounds 3-Deoxyglucosone, Glyoxal, and Methylglyoxal Are Not Increased in Healthy Older Adults.
Topics: Aged; Animals; Deoxyglucose; Fasting; Female; Glucose; Glyoxal; Humans; Insulins; Magnesium Oxide; Male; Mice; Mice, Inbred C57BL; Pyruvaldehyde | 2022 |