3-demethylthiocolchicine has been researched along with colchicine in 7 studies
*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]
*Colchicine: A major alkaloid from Colchicum autumnale L. and found also in other Colchicum species. Its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial Mediterranean fever (PERIODIC DISEASE). [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brossi, A; Hamel, E; Lin, CM; Muzaffar, A | 1 |
| Brossi, A; Chignell, CF; Dumont, R; Quinn, FR; Suffness, M | 1 |
| Brossi, A; Chignell, CF; Kerekes, P; Quinn, FR; Sharma, PN | 1 |
| Bastow, KF; Brossi, A; Guan, J; Hamel, E; Lee, KH; Tachibana, Y; Zhu, XK | 1 |
| Brossi, A; Feng, J; Hamel, E; Kuo, SC; Lee, KH; Tropsha, A; Zhang, SX | 1 |
| Brossi, A; Gotfried, M; Jedeikin, A; Lishner, M; Ravid, M; Wolach, B | 1 |
| Els, J; Herbst, L; Hundt, AF; Hundt, HK; Smit, MJ; Sutherland, FC; Swart, KJ | 1 |
7 other study(ies) available for 3-demethylthiocolchicine and colchicine
| Article | Year |
|---|---|
Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoids.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Division; Chemical Phenomena; Chemistry; Colchicine; In Vitro Techniques; Ketones; Leukemia L1210; Polymers; Protein Binding; Structure-Activity Relationship; Sulfides; Tubulin; Tumor Cells, Cultured | 1990 |
A novel synthesis of colchicide and analogues from thiocolchicine and congeners: reevaluation of colchicide as a potential antitumor agent.
Topics: Animals; Antineoplastic Agents; Colchicine; Mice; Neoplasms, Experimental; Structure-Activity Relationship; Tubulin | 1987 |
Synthesis and biological effects of novel thiocolchicines. 3. Evaluation of N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl) deacetylthiocolchicines, and O-ethyldemethylthiocolchicines. New synthesis of thiodemecolcine and antileukemic effects of 2-demet
Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Colchicine; Demecolcine; Drug Evaluation; Lethal Dose 50; Leukemia P388; Leukemia, Experimental; Mice; Structure-Activity Relationship; Tubulin | 1985 |
Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cell Division; Colchicine; DNA; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; KB Cells; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators; Tumor Cells, Cultured | 1998 |
Antitumor agents. 199. Three-dimensional quantitative structure-activity relationship study of the colchicine binding site ligands using comparative molecular field analysis.
Topics: Antineoplastic Agents; Colchicine; Molecular Structure; Static Electricity; Structure-Activity Relationship | 2000 |
Colchicine analogues: effect on amyloidogenesis in a murine model and, in vitro, on polymorphonuclear leukocytes.
Topics: Amyloid; Amyloidosis; Animals; Chemotaxis; Colchicine; Humans; Mice; Neutrophils; Phagocytosis | 1992 |
Highly specific and sensitive liquid chromatography-tandem mass spectrometry method for the determination of 3-desmethylthiocolchicine in human plasma as analyte for the assessment of bioequivalence after oral administration of thiocolchicoside.
Topics: Administration, Oral; Chromatography, Liquid; Colchicine; GABA Agonists; Half-Life; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency | 2002 |