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3-deazaneplanocin and s-adenosylhomocysteine

3-deazaneplanocin has been researched along with s-adenosylhomocysteine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK1
Bu, G; Oxenrider, KA; Sitz, TO1
Tsiftsoglou, AS; Vizirianakis, IS1
Clark, SH; Hamre, MR; Mirkin, BL1
Bray, M; Driscoll, J; Huggins, JW1
Anderson, TD; Sharakhov, IV; Sharma, A1
Du, Z; Gao, Y; Luo, Y; Wang, N; Wang, P; Wu, G; Yang, B; Zhang, Y; Zhu, Z1
Adouane, D; Aury-Landas, J; Baugé, C; Boumediene, K; Delépée, R; Girard, N; Lhuissier, E1
Chen, HW; Han, F; Liu, P; Wang, J; Wang, Q; Xiang, S; Xu, J; Zheng, J; Zou, JX1

Other Studies

9 other study(ies) available for 3-deazaneplanocin and s-adenosylhomocysteine

ArticleYear
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine

1986
Adenosine analogs inhibit the guanine-7-methylation of mRNA cap structures.
    FEBS letters, 1993, Feb-01, Volume: 316, Issue:3

    Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; In Vitro Techniques; Methylation; Methyltransferases; Mice; RNA Caps; S-Adenosylhomocysteine

1993
Induction of murine erythroleukemia cell differentiation is associated with methylation and differential stability of poly(A)+ RNA transcripts.
    Biochimica et biophysica acta, 1996, Jun-05, Volume: 1312, Issue:1

    Topics: Actins; Adenosine; Animals; Cell Differentiation; Cell Division; Cycloleucine; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Globins; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Proto-Oncogene Proteins c-myc; Ribonucleotides; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured

1996
Resistance to inhibitors of S-adenosyl-L-homocysteine hydrolase in C1300 murine neuroblastoma tumor cells is associated with increased methionine adenosyltransferase activity.
    Oncology research, 1995, Volume: 7, Issue:10-11

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Cell Division; Drug Resistance, Neoplasm; Enzyme Inhibitors; Hydrolases; Male; Methionine Adenosyltransferase; Methylation; Mice; Mice, Inbred A; Neuroblastoma; S-Adenosylhomocysteine; S-Adenosylmethionine; Tritium; Tumor Cells, Cultured

1995
Treatment of lethal Ebola virus infection in mice with a single dose of an S-adenosyl-L-homocysteine hydrolase inhibitor.
    Antiviral research, 2000, Volume: 45, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Cell Line; Dose-Response Relationship, Drug; Ebolavirus; Enzyme Inhibitors; Female; Hemorrhagic Fever, Ebola; Hydrolases; Mice; Mice, Inbred BALB C; Mice, SCID; S-Adenosylhomocysteine; Tubercidin

2000
Toxicological assays for testing effects of an epigenetic drug on development, fecundity and survivorship of malaria mosquitoes.
    Journal of visualized experiments : JoVE, 2015, Jan-16, Issue:95

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Anopheles; Dose-Response Relationship, Drug; Female; Fertility; Insect Vectors; Insecticide Resistance; Insecticides; Malaria; Male; Mosquito Control; S-Adenosylhomocysteine; Survival Rate

2015
Metabolic perturbation of epigenome by inhibiting S-adenosylhomocysteine hydrolase elicits senescence through DNA damage response in hepatoma cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Adenosine; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Hepatocellular; Cell Proliferation; Cellular Senescence; Chromatin; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Epigenomics; Hep G2 Cells; Histones; Humans; Liver Neoplasms; Metabolic Networks and Pathways; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Suppressor Protein p53

2017
The Antitumoral Effect of the S-Adenosylhomocysteine Hydrolase Inhibitor, 3-Deazaneplanocin A, is Independent of EZH2 but is Correlated with EGFR Downregulation in Chondrosarcomas.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 53, Issue:4

    Topics: Adenosine; Animals; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Chondrosarcoma; DNA Damage; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; ErbB Receptors; Histones; Humans; Male; Mice; Mice, Nude; Protein Interaction Maps; RNA Interference; RNA, Small Interfering; S-Adenosylhomocysteine

2019
S-adenosylhomocysteine (AdoHcy)-dependent methyltransferase inhibitor DZNep overcomes breast cancer tamoxifen resistance via induction of NSD2 degradation and suppression of NSD2-driven redox homeostasis.
    Chemico-biological interactions, 2020, Feb-01, Volume: 317

    Topics: Adenosine; Antigens, Ly; Apoptosis; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; Histone-Lysine N-Methyltransferase; Homeostasis; Humans; Methyltransferases; Oxidation-Reduction; Proteolysis; Reactive Oxygen Species; Repressor Proteins; S-Adenosylhomocysteine; Tamoxifen; Urokinase-Type Plasminogen Activator

2020