3-deazaneplanocin has been researched along with panobinostat in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Atadja, P; Balusu, R; Bhalla, KN; Buckley, KM; Chen, J; Fernandez, P; Fiskus, W; Jillella, A; Koul, S; Marquez, VE; Rao, R; Shi, H; Sreekumar, A; Ustun, C; Wang, Y | 1 |
| Agarwal, P; Atadja, P; Deleu, S; Eriksson, M; Fristedt, C; Fryknäs, M; Jernberg-Wiklund, H; Kalushkova, A; Lemaire, M; Nilsson, K; Oberg, F; Osterborg, A; Vanderkerken, K | 1 |
| Choi, YL; Hasegawa, H; Hayashi, T; Imaizumi, Y; Kamihira, S; Mano, H; Marquez, VE; Miyazaki, Y; Moriwaki, Y; Osaka, A; Sasaki, D; Tsukasaki, K; Yamada, Y; Yanagihara, K | 1 |
| Atadja, P; Balusu, R; Bhalla, K; Fiskus, W; Ganguly, S; Hembruff, SL; Marquez, VE; Mudunuru, U; Rao, R; Smith, JE; Sotomayor, E; Tao, J | 1 |
| Castresana, JS; De La Rosa, J; Idoate, MA; Meléndez, B; Rey, JA; Urdiciain, A; Zazpe, I; Zelaya, MV | 2 |
6 other study(ies) available for 3-deazaneplanocin and panobinostat
| Article | Year |
|---|---|
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carrier Proteins; Cell Cycle; DNA-Binding Proteins; Drug Evaluation, Preclinical; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; HL-60 Cells; Humans; Hydroxamic Acids; Indoles; Leukemia, Myeloid, Acute; Neoplasm Proteins; Nuclear Proteins; Panobinostat; Polycomb Repressive Complex 2; Transcription Factors; Treatment Outcome; Tumor Cells, Cultured | 2009 |
Polycomb target genes are silenced in multiple myeloma.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Apoptosis; Blotting, Western; Cadherins; Cell Line, Tumor; Cells, Cultured; Chemokine CXCL12; Chromatin Immunoprecipitation; Computational Biology; DNA Methylation; GATA2 Transcription Factor; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Interferon Regulatory Factors; Kaplan-Meier Estimate; Mice; Multiple Myeloma; Panobinostat; Polycomb-Group Proteins; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Overexpression of Enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic therapy.
Topics: Adenosine; Base Sequence; Blotting, Western; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Epigenomics; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Histones; Humans; Hydroxamic Acids; Indoles; Intracellular Signaling Peptides and Proteins; Leukemia-Lymphoma, Adult T-Cell; Lysine; Methylation; MicroRNAs; Oligonucleotide Array Sequence Analysis; Panobinostat; Polycomb Repressive Complex 1; Polycomb Repressive Complex 2; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors | 2011 |
Superior efficacy of a combined epigenetic therapy against human mantle cell lymphoma cells.
Topics: Adenosine; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Lymphoma, Mantle-Cell; Mice; Mice, Inbred NOD; Mice, SCID; Muscle Proteins; Neoplasm Proteins; Panobinostat; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Binding; RNA Interference; SKP Cullin F-Box Protein Ligases; Transcription Factors; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
The synergistic effect of DZ‑NEP, panobinostat and temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Panobinostat; Temozolomide; Tumor Cells, Cultured | 2020 |
APR-246 combined with 3-deazaneplanocin A, panobinostat or temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
Topics: Adenosine; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Drug Screening Assays, Antitumor; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mutation; Panobinostat; Quinuclidines; Temozolomide; Tumor Suppressor Protein p53 | 2021 |