Page last updated: 2024-08-25

3-deazaneplanocin and neplanocin a

3-deazaneplanocin has been researched along with neplanocin a in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chandra, G; Chang, TS; Choi, S; Jang, JY; Jeong, LS; Kim, G; Lee, SK; Lee, Y; Moon, YW; Mulamoottil, VA; Nayak, A; Noh, M; Oh, K; Sahu, PK; Song, J1
Balzarini, J; Borchardt, RT; Borcherding, DR; Cools, M; De Clercq, E; Drach, JC; Kitaoka, S; Konno, T; Marquez, VE1
De Clercq, E1
Chiang, PK; Glazer, RI; Hartman, KD; Knode, MC; Marquez, VE; Richard, MM; Tseng, CK1
Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK1
Bu, G; Oxenrider, KA; Sitz, TO1
Tsiftsoglou, AS; Vizirianakis, IS2
Amanatiadou, EP; Tezias, SS; Tsiftsoglou, AS; Vizirianakis, IS1
Chai, CL; Goh, YL; Hill, J; Jiang, X; Lee, PL; Li, Z; Lim, CZ; Nguyen, TM; Ong, EH; Santhanakrishnan, S; Tam, EK; Tan, TW; Wong, SY; Yang, H; Yu, Q1
Chen, F; Deng, L; Mo, Q; Song, Y; Wei, L; Wu, B; Yao, Y; Zhang, L1

Reviews

1 review(s) available for 3-deazaneplanocin and neplanocin a

ArticleYear
S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents.
    Biochemical pharmacology, 1987, Aug-15, Volume: 36, Issue:16

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Antiviral Agents; Hydrolases; Models, Biological; Tubercidin; Virus Replication

1987

Other Studies

10 other study(ies) available for 3-deazaneplanocin and neplanocin a

ArticleYear
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses

2015
Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivatives.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:8

    Topics: Adenosine; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; HeLa Cells; Mice; Reoviridae; Respirovirus; Rotavirus; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus; Virus Replication

1989
3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Humans; Hydrolases; Leukemia, Myeloid, Acute; Liver

1986
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine

1986
Adenosine analogs inhibit the guanine-7-methylation of mRNA cap structures.
    FEBS letters, 1993, Feb-01, Volume: 316, Issue:3

    Topics: Adenosine; Animals; Carcinoma, Ehrlich Tumor; In Vitro Techniques; Methylation; Methyltransferases; Mice; RNA Caps; S-Adenosylhomocysteine

1993
Induction of murine erythroleukemia cell differentiation is associated with methylation and differential stability of poly(A)+ RNA transcripts.
    Biochimica et biophysica acta, 1996, Jun-05, Volume: 1312, Issue:1

    Topics: Actins; Adenosine; Animals; Cell Differentiation; Cell Division; Cycloleucine; Dimethyl Sulfoxide; Erythrocytes; Erythropoiesis; Globins; Hemoglobins; Kinetics; Leukemia, Erythroblastic, Acute; Methylation; Mice; Neoplasm Proteins; Peroxidases; Peroxiredoxin III; Peroxiredoxins; Proto-Oncogene Proteins c-myc; Ribonucleotides; RNA Caps; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured

1996
Blockade of murine erythroleukemia cell differentiation by hypomethylating agents causes accumulation of discrete small poly(A)- RNAs hybridized to 3'-end flanking sequences of beta(major) globin gene.
    Biochimica et biophysica acta, 2005, Mar-22, Volume: 1743, Issue:1-2

    Topics: Adenosine; Animals; Base Sequence; Blotting, Northern; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cycloleucine; Cytoplasm; Dimethyl Sulfoxide; DNA; DNA Methylation; DNA Primers; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Globins; Kruppel-Like Transcription Factors; Leukemia, Erythroblastic, Acute; Mice; Models, Genetic; Molecular Sequence Data; Poly A; Repressor Proteins; RNA; RNA, Messenger; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation

2005
Cloning and characterization of polyA- RNA transcripts encoded by activated B1-like retrotransposons in mouse erythroleukemia MEL cells exposed to methylation inhibitors.
    BMB reports, 2012, Volume: 45, Issue:2

    Topics: Adenosine; Animals; beta-Globins; Cell Differentiation; Cell Line, Tumor; Cloning, Molecular; Cycloleucine; Dimethyl Sulfoxide; DNA Methylation; Leukemia, Erythroblastic, Acute; Mice; Molecular Sequence Data; Poly A; Retroelements; RNA

2012
3-Deazaneplanocin A and neplanocin A analogues and their effects on apoptotic cell death.
    ChemMedChem, 2015, Volume: 10, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Structure-Activity Relationship; Transplantation, Heterologous

2015
Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
    Oncotarget, 2014, Nov-15, Volume: 5, Issue:21

    Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Movement; Cell Proliferation; DNA Methylation; Enzyme Inhibitors; Female; Flow Cytometry; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunoenzyme Techniques; Lysine; Methyltransferases; Mice; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2014