Page last updated: 2024-08-25

3-deazaneplanocin and epz-6438

3-deazaneplanocin has been researched along with epz-6438 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Li, J; Liang, C; Liu, C; Ren, X; Tian, L; Xia, J1
Alahmari, B; Choi, J; Cooper, M; DiPersio, JF; Ritchey, J; Ziga, E1
Du, W; Duan, R; Guo, W1
Amin, SG; Belinsky, SA; Desai, DH; Do, K; Filipczak, PT; Hutt, JA; Juri, D; Picchi, MA; Tellez, CS1

Reviews

2 review(s) available for 3-deazaneplanocin and epz-6438

ArticleYear
Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects.
    Journal of medicinal chemistry, 2022, 05-26, Volume: 65, Issue:10

    Topics: Animals; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Hematologic Neoplasms; Histone Methyltransferases; Humans; Molecular Targeted Therapy; Neoplasms; Structure-Activity Relationship

2022
EZH2: a novel target for cancer treatment.
    Journal of hematology & oncology, 2020, 07-28, Volume: 13, Issue:1

    Topics: Adenosine; Antineoplastic Agents; Benzamides; Biphenyl Compounds; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Histone Code; Histones; Humans; Methylation; Morpholines; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship; Transcriptional Activation; Tumor Microenvironment

2020

Other Studies

2 other study(ies) available for 3-deazaneplanocin and epz-6438

ArticleYear
Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Adenosine; Animals; Benzamides; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histone Code; Histones; Humans; Indoles; Methylation; Mice; Morpholines; Pyridones; T-Lymphocytes

2018
Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention.
    Clinical epigenetics, 2021, 02-25, Volume: 13, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Benzamides; Biphenyl Compounds; Cell Proliferation; Chromatin Assembly and Disassembly; CpG Islands; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial Cells; Female; Histone Code; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lung Neoplasms; Mice; Morpholines; Neoplasms; Phenotype; Pyridones; Transcriptome

2021