Page last updated: 2024-09-03

3-deazaguanosine and 3-deazaguanine

3-deazaguanosine has been researched along with 3-deazaguanine in 12 studies

Compound Research Comparison

Studies
(3-deazaguanosine)
Trials
(3-deazaguanosine)
Recent Studies (post-2010)
(3-deazaguanosine)
Studies
(3-deazaguanine)
Trials
(3-deazaguanine)
Recent Studies (post-2010) (3-deazaguanine)
26024415

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199011 (91.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, LB; Cook, PD; Huffman, JH; Robins, RK; Sidwell, RW; Streeter, DG1
Berry, DA; Cook, PD; Gilbertsen, RB1
Adams, AD; Canonico, PG; Cook, PD; Dalley, NK; Gupta, PK; McKernan, PA; Revankar, GR; Robins, RK1
Khwaja, TA; Mian, AM1
Cook, PD; Dea, P; Meyer, RB; Mian, AM; Robins, RK; Rousseau, RJ1
Cook, PD; Dea, P; Ivanovics, G; Meyer, RB; Mian, AM; Rousseau, RJ1
Plunkett, W; Saunders, PP1
Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, TM; Robins, RK1
Plunkett, W; Robins, RK; Saunders, PP; Spindler, CD; Tan, MT1
Chiang, PK; Lucas, DL; Robins, RK; Webster, HK; Wiesmann, WP; Wright, DG1
Berman, JD; Lee, LS; Revankar, GR; Robins, RK1
Chao, LY; Loo, TL; Robins, RK; Saunders, PP1

Reviews

1 review(s) available for 3-deazaguanosine and 3-deazaguanine

ArticleYear
Metabolism and action of purine nucleoside analogs.
    Pharmacology & therapeutics, 1991, Volume: 49, Issue:3

    Topics: 2-Chloroadenosine; Adenosine; Cladribine; Deoxyadenosines; Guanine; Guanosine; Humans; Purine Nucleosides; Ribavirin; Vidarabine

1991

Other Studies

11 other study(ies) available for 3-deazaguanosine and 3-deazaguanine

ArticleYear
Synthesis and antiviral and enzymatic studies of certain 3-deazaguanines and their imidazolecarboxamide precursors.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:12

    Topics: Adenylosuccinate Synthase; Animals; Anti-Infective Agents; Antiviral Agents; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytopathogenic Effect, Viral; Guanine; Imidazoles; IMP Dehydrogenase; Male; Mice; Orthomyxoviridae Infections; Purine Nucleotides; Ribavirin

1978
Synthesis of 8-amino-3-deazaguanine via imidazole precursors. Antitumor activity and inhibition of purine nucleoside phosphorylase.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:10

    Topics: Animals; Antineoplastic Agents; Guanine; Humans; Leukemia L1210; Lymphocytes; Pentosyltransferases; Purine-Nucleoside Phosphorylase; Structure-Activity Relationship

1986
Synthesis and antiviral/antitumor activities of certain 3-deazaguanine nucleosides and nucleotides.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:11

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Guanine; Guanosine; Leukemia L1210; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Parainfluenza Virus 3, Human; Simplexvirus; Vaccinia virus; Vesicular stomatitis Indiana virus

1984
synthesis and antitumor activity of 2-deoxyribofuranosides of 3-deazaguanine.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Deoxyribose; Female; Guanosine; Indicators and Reagents; Isomerism; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Structure-Activity Relationship

1983
Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors.
    Journal of the American Chemical Society, 1976, Mar-17, Volume: 98, Issue:6

    Topics: Animals; Antimetabolites; Guanine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Imidazoles; Methods; Mice

1976
Letter: A new class of potent guanine antimetabolites. Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors.
    Journal of the American Chemical Society, 1975, May-14, Volume: 97, Issue:10

    Topics: Antimetabolites; Cyclization; Guanine; Guanine Nucleotides; Guanosine; Guanosine Monophosphate; Imidazoles; Methods

1975
The metabolism of 3-deazaguanine and 3-deazaguanosine by human cells in culture.
    The International journal of biochemistry, 1986, Volume: 18, Issue:10

    Topics: Cells, Cultured; DNA; Fibroblasts; Guanine; Guanosine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Mutation; Phosphorylation; RNA

1986
3-Deazaguanosine is metabolized to the triphosphate derivative in Chinese hamster cells deficient in hypoxanthine-guanine phosphoribosyltransferase.
    The Journal of biological chemistry, 1986, May-15, Volume: 261, Issue:14

    Topics: Alkaline Phosphatase; Animals; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Female; Formates; Guanine; Guanosine; Guanosine Triphosphate; Hypoxanthine Phosphoribosyltransferase; Inosine; Ovary; Thymidine

1986
Effects of 3-deazaguanosine and 3-deazaguanine on the growth and maturation of the human promyelocytic leukemia cell line, HL-60.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Antimetabolites; Cell Division; Cell Line; Guanine; Guanosine; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid, Acute; Mycophenolic Acid

1984
Activity of purine analogs against Leishmania tropica within human macrophages in vitro.
    Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:2

    Topics: Allopurinol; Antiprotozoal Agents; Formycins; Guanine; Guanosine; Humans; In Vitro Techniques; Leishmania; Macrophages; Purines; Ribonucleosides; Thionucleosides

1983
Actions of 3-deazaguanine and 3-deazaguanosine on variant lines of Chinese hamster ovary cells.
    Biochemical pharmacology, 1981, Aug-15, Volume: 30, Issue:16

    Topics: Adenine Phosphoribosyltransferase; Adenosine Kinase; Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; Cricetulus; Deoxycytidine Kinase; Female; Guanine; Guanosine; Hypoxanthine Phosphoribosyltransferase; Ovary; Purine Nucleotides

1981