Page last updated: 2024-08-25

3-deazaaristeromycin and adenosine

3-deazaaristeromycin has been researched along with adenosine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199018 (56.25)18.7374
1990's11 (34.38)18.2507
2000's1 (3.13)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergogne, MC; De Clercq, E; De Rudder, J; Gosselin, G; Imbach, JL1
Ackerman, JJ; Buttz, HR; Duerre, JA1
Aarbakke, J; Andersen, A; Loennechen, T; Moens, U; Nilsen, IW1
Allen, T; Coulter-Karis, DE; Greenberg, ML; Hanson, S; Henderson, DM; Hershfield, MS; Ullman, B; Wilson, K1
Bozzi, A; Corbo, RM; Ingianna, R; Scacchi, R1
Aarbakke, J; Bang, BE; Endresen, PC; Møller, C; Prytz, PS1
Fischer, AA; Müller, K; Scholtissek, C1
Ledoux, DN; Smith, JD1
Aarbakke, J; Prytz, PS1
Dalaker, K; Prydz, H1
Aarbakke, J; Loennechen, T; Prytz, PS1
Chaffee, S; Greenberg, ML; Hershfield, MS1
Djurhuus, R; Svardal, AM; Ueland, PM1
Liteplo, RG1
Chiang, PK; Glazer, RI; Hartman, KD; Knode, MC; Marquez, VE; Richard, MM; Tseng, CK1
Aarbakke, J; Bessesen, A; Chiang, PK; Gordon, RK; Miura, GA; Prytz, PS; Slørdal, L1
Finbloom, DS; Gordon, RK; Martin, J1
Djurhuus, R; Refsum, H; Svardal, AM; Ueland, PM1
Backlund, PS; Cantoni, GL; Carotti, D1
Glazer, RI; Haines, DR; Knode, MC; Marquez, VE; Tseng, CK1
Aksamit, RR; Backlund, PS1
Aksamit, RR; Backlund, PS; Bozzi, A; Cantoni, GL; Chen, J; Scarpa, S; Strom, R1
Chiang, PK1
Brown, ND; Chiang, PK; Gordon, RK1
Chiang, PK; Montgomery, JA; Shattil, SJ1
Aksamit, RR; Cantoni, GL; Kim, IK1
Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T1
Cheong, CH; Hong, SH; Jeong, SY; Kim, HS; Kim, IK; Lee, JH1
Loennechen, T; Svendsrud, DH; Winberg, JO1
Bujnicki, JM; Caridha, D; Chiang, PK; Prigge, ST1
Chen, Q; Liu, C; Schneller, SW1
Chen, Q; Gorden, JD; Liu, C; Schneller, SW1

Reviews

1 review(s) available for 3-deazaaristeromycin and adenosine

ArticleYear
Chemotaxis and methylation in a macrophage cell line.
    Survey of immunologic research, 1983, Volume: 2, Issue:2

    Topics: Adenine; Adenosine; Animals; Blood Proteins; Cell Line; Chemotaxis, Leukocyte; Guinea Pigs; Humans; Macrophages; Methylation; Mice; Phosphatidylethanolamines; Rabbits; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin

1983

Other Studies

31 other study(ies) available for 3-deazaaristeromycin and adenosine

ArticleYear
Systematic synthesis and biological evaluation of alpha- and beta-D-lyxofuranosyl nucleosides of the five naturally occurring nucleic acid bases.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:6

    Topics: Animals; Antiviral Agents; Herpes Simplex; Mice; Nucleosides

1987
Effect of methylation inhibitors on gene expression in HL-60 cells.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1992, Volume: 70, Issue:8

    Topics: Adenosine; Cell Differentiation; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Methylation; Poly A; RNA, Messenger; RNA, Neoplasm; Tretinoin; Tubercidin; Tumor Cells, Cultured

1992
Is there an association between an increase in c-myc RNA steady state levels and c-myc methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin, an indirect inhibitor of methylation?
    Biochemical pharmacology, 1992, Oct-06, Volume: 44, Issue:7

    Topics: Adenosine; Cell Nucleus; DNA; Genes, myc; Humans; Methylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Restriction Mapping; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Tumor Cells, Cultured

1992
Cloning of the gene encoding Leishmania donovani S-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy.
    Molecular and biochemical parasitology, 1992, Volume: 53, Issue:1-2

    Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Protozoan; Hydrolases; Leishmania donovani; Molecular Sequence Data; Restriction Mapping; RNA, Messenger; RNA, Protozoan

1992
Kinetic properties of the common electrophoretic variants of human S-adenosylhomocysteine hydrolase (AHCY): the effect of four nucleoside analogue inhibitors.
    Annals of human genetics, 1992, Volume: 56, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Adenosylhomocysteinase; Anti-Bacterial Agents; Enzyme Inhibitors; Erythrocytes; Humans; Hydrolases; Isomerism; Kinetics; Purine Nucleosides; Ribonucleosides; Tubercidin

1992
Elevation of cyclic AMP levels in HL-60 cells accumulated in G1 or G2 by transmethylation inhibitors.
    Biochemical pharmacology, 1991, Oct-09, Volume: 42, Issue:9

    Topics: Adenosine; Cell Division; Cell Line; Cyclic AMP; Flow Cytometry; G1 Phase; G2 Phase; Homocysteine; Humans; Leukemia; Methyltransferases; Tubercidin

1991
Specific inhibition of the synthesis of influenza virus late proteins and stimulation of early, M2, and NS2 protein synthesis by 3-deazaadenosine.
    Virology, 1990, Volume: 177, Issue:2

    Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Capsid; Cell Line; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Influenza A virus; Isomerism; Kinetics; Mice; RNA, Messenger; RNA, Viral; Tubercidin; Viral Core Proteins; Viral Nonstructural Proteins; Viral Proteins; Virus Replication

1990
Effect of the methylation inhibitors 3-deazaadenosine and 3-deazaaristeromycin on phosphatidylcholine formation in Tetrahymena.
    Biochimica et biophysica acta, 1990, Dec-04, Volume: 1047, Issue:3

    Topics: Adenosine; Animals; Carbon Radioisotopes; Choline; Enzyme Inhibitors; Isomerism; Kinetics; Methionine; Phosphatidylcholines; Tetrahymena; Tritium; Tubercidin

1990
Differential cell cycle perturbation by transmethylation inhibitors.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Aminoglycosides; Anti-Bacterial Agents; Cell Cycle; Enzyme Inhibitors; Flow Cytometry; Humans; Hydrolases; Interphase; Kinetics; Leukemia, Promyelocytic, Acute; Methylation; Mitosis; Tubercidin; Tumor Cells, Cultured

1990
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil

1986
DNA-methylation in HL-60 cells treated with 3-deaza-(+/-)-aristeromycin and 3-deazaadenosine.
    Biochemical pharmacology, 1989, Aug-15, Volume: 38, Issue:16

    Topics: 5-Methylcytosine; Adenosine; Aminoglycosides; Anti-Bacterial Agents; Cell Count; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; Enzyme Inhibitors; Humans; Stereoisomerism; Tubercidin

1989
Basis for resistance to 3-deazaaristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase, in human B-lymphoblasts.
    The Journal of biological chemistry, 1989, Jan-15, Volume: 264, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; B-Lymphocytes; Cell Line; Clone Cells; Drug Resistance; Enzyme Inhibitors; Humans; Hydrolases; Isomerism; Kinetics; Tubercidin

1989
Differential effects on growth, homocysteine, and related compounds of two inhibitors of S-adenosylhomocysteine catabolism, 3-deazaadenosine, and 3-deazaaristeromycin, in C3H/10T1/2 cells.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Homocysteine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; Tubercidin

1989
DNA (cytosine) methylation in murine and human tumor cell lines treated with S-adenosylhomocysteine hydrolase inhibitors.
    Cancer letters, 1988, Volume: 39, Issue:3

    Topics: Adenosine; Adenosylhomocysteinase; Animals; DNA, Neoplasm; Humans; Hydrolases; Methylation; Mice; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin; Tumor Cells, Cultured

1988
3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60.
    Biochemical and biophysical research communications, 1986, Mar-13, Volume: 135, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Humans; Hydrolases; Leukemia, Myeloid, Acute; Liver

1986
Induction of HL-60 cell differentiation by 3-deaza-(+/-)-aristeromycin, an inhibitor of S-adenosylhomocysteine hydrolase.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: Adenosine; Adenosylhomocysteinase; Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Humans; Hydrolases; Leukemia, Myeloid, Acute; S-Adenosylhomocysteine; S-Adenosylmethionine

1986
Endocytosis of particulate and soluble IgG immune complexes: differential effects of cytoskeletal modulating agents.
    Clinical and experimental immunology, 1987, Volume: 67, Issue:1

    Topics: Adenosine; Animals; Antigen-Antibody Complex; Colchicine; Cytochalasin B; Cytoskeleton; Endocytosis; Immunoglobulin G; Methylation; Mice; Mice, Inbred C3H; Phospholipids; Tubercidin

1987
Disposition of homocysteine in rat hepatocytes and in nontransformed and malignant mouse embryo fibroblasts following exposure to inhibitors of S-adenosylhomocysteine catabolism.
    Cancer research, 1986, Volume: 46, Issue:10

    Topics: Adenine; Adenosine; Adenosine Triphosphate; Adenosylhomocysteinase; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Homocysteine; Hydrolases; In Vitro Techniques; Liver; Methionine; Rats; S-Adenosylhomocysteine

1986
Effects of the S-adenosylhomocysteine hydrolase inhibitors 3-deazaadenosine and 3-deazaaristeromycin on RNA methylation and synthesis.
    European journal of biochemistry, 1986, Oct-15, Volume: 160, Issue:2

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cells, Cultured; Hydrolases; Methylation; Ribonucleosides; RNA, Messenger; S-Adenosylhomocysteine; Tubercidin

1986
3-Deazaneplanocin A: a new inhibitor of S-adenosylhomocysteine synthesis and its effects in human colon carcinoma cells.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Cell Line; Colonic Neoplasms; Humans; Hydrolases; Kinetics; Methionine; Methylation; RNA, Ribosomal; RNA, Transfer; S-Adenosylhomocysteine; Uridine

1986
Differentiation of myoblast cell lines and biological methylation: 3-deazaadenosine stimulates formation of multinucleated myofibers.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:10

    Topics: Adenosine; Animals; Animals, Newborn; Cell Differentiation; Cell Line; Clone Cells; Creatine Kinase; DNA; Enzyme Inhibitors; Isomerism; Muscles; Rats; Ribonucleosides; Tubercidin

1984
S-adenosylhomocysteine hydrolase as a pharmacological target for the inhibition of transmethylation.
    Advances in experimental medicine and biology, 1984, Volume: 165 Pt B

    Topics: Adenosine; Animals; Enzyme Inhibitors; Homocysteine; Isomerism; Kinetics; Mice; Ribonucleosides; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin

1984
Inhibition of adenosylmethionine decarboxylase and perturbation of polyamine metabolism by 3-deaza-(+/-)aristeromycin.
    Biochemical and biophysical research communications, 1983, Jul-29, Volume: 114, Issue:2

    Topics: Adenosine; Adenosylmethionine Decarboxylase; Carboxy-Lyases; Enzyme Inhibitors; HeLa Cells; Humans; Kinetics; Polyamines

1983
The effect of pharmacologic inhibition of phospholipid methylation on human platelet function.
    Blood, 1982, Volume: 59, Issue:5

    Topics: Adenosine; Adenosylhomocysteinase; Blood Platelets; Humans; Hydrolases; Methylation; Phosphatidylethanolamines; Phospholipids; Platelet Aggregation; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin

1982
Mechanism of the cytostatic activity of 3-deazaaristeromycin, an inhibitor of adenosylhomocysteine hydrolase.
    The Journal of biological chemistry, 1982, Dec-25, Volume: 257, Issue:24

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Division; Cell Line; Hydrolases; Hypoxanthine; Hypoxanthines; Kinetics; Macrophages; Mice; Thymidine

1982
Apoptosis and transmethylation metabolites in HL-60 cells.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin

1996
3-Deazaadenosine analogues inhibit the production of tumour necrosis factor-alpha in RAW264.7 cells stimulated with lipopolysaccharide.
    Immunology, 1996, Volume: 89, Issue:4

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Cell Line; Depression, Chemical; Hydrolases; Interleukin-1; Isomerism; Lipopolysaccharides; Macrophages; Mice; Protein Biosynthesis; Transcription, Genetic; Tubercidin; Tumor Necrosis Factor-alpha

1996
Effect of adenosine analogues on the expression of matrix metalloproteinases and their inhibitors from human dermal fibroblasts.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Adenosine; Adenosylhomocysteinase; Cell Survival; Cells, Cultured; Collagenases; DNA Fragmentation; Enzyme Inhibitors; Fibroblasts; Gelatinases; Glycoproteins; Humans; Hydrolases; Matrix Metalloproteinase 3; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Protease Inhibitors; Skin; Tissue Inhibitor of Metalloproteinases; Tubercidin

1997
Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.
    Proteins, 2003, Sep-01, Volume: 52, Issue:4

    Topics: Adenosine; Adenosylhomocysteinase; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Evolution, Molecular; Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Phylogeny; Plasmodium falciparum; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Tubercidin

2003
3-Bromo-3-deazaneplanocin and 3-bromo-3-deazaaristeromycin: synthesis and antiviral activity.
    Bioorganic & medicinal chemistry letters, 2012, Aug-15, Volume: 22, Issue:16

    Topics: Adenosine; Animals; Antiviral Agents; Cell Line; Cell Survival; Chlorocebus aethiops; Crystallography, X-Ray; HeLa Cells; Humans; Molecular Conformation; Vero Cells; Virus Replication; Viruses

2012
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral properties.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Adenosine; Antiviral Agents; Humans; Molecular Structure

2015