3-cyclobutene-1,2-dione has been researched along with 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid in 1 studies
*3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist [MeSH]
*3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid: structure given in first source; NMDA receptor antagonist [MeSH]
| Studies (3-cyclobutene-1,2-dione) | Trials (3-cyclobutene-1,2-dione) | Recent Studies (post-2010) (3-cyclobutene-1,2-dione) | Studies (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid) | Trials (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid) | Recent Studies (post-2010) (3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 755 | 2 | 65 |
| Protein | Taxonomy | 3-cyclobutene-1,2-dione (IC50) | 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1139 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1139 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abou-Gharbia, M; Bramlett, DR; Garrison, DT; Kinney, WA; Kowal, DM; Miller, TL; Moyer, JA; Schmid, J; Tasse, RP; Zaleska, MM | 1 |
1 other study(ies) available for 3-cyclobutene-1,2-dione and 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid
| Article | Year |
|---|---|
Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere.
Topics: Animals; Azabicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclobutanes; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Ischemic Attack, Transient; Mice; Models, Chemical; N-Methylaspartate; Organophosphonates; Pipecolic Acids; Piperazines; Rats | 1998 |