Compounds > 3-cyano-7-ethoxycoumarin
Page last updated: 2024-09-05

3-cyano-7-ethoxycoumarin and warfarin

3-cyano-7-ethoxycoumarin has been researched along with warfarin in 6 studies

Compound Research Comparison

Studies
(3-cyano-7-ethoxycoumarin)		Trials
(3-cyano-7-ethoxycoumarin)		Recent Studies (post-2010)
(3-cyano-7-ethoxycoumarin)		Studies
(warfarin)		Trials
(warfarin)		Recent Studies (post-2010) (warfarin)
60336,5732,14314,728

Protein Interaction Comparison

ProteinTaxonomy3-cyano-7-ethoxycoumarin (IC50)warfarin (IC50)
Vitamin K epoxide reductase complex subunit 1 Homo sapiens (human)0.0088

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
White, IN1
Dinsdale, D; Martin, J; White, IN1
Chou, KC; Li, L; Li, YX; Wang, JF; Wei, DQ; Zheng, SY1
Chen, C; Gao, Y; Kim, RA; Sun, D; Wang, H; Zhu, J1
Chibale, K; Dhansay, K; Masimirembwa, CM; Smith, P; Thelingwani, RS1
Ahemad, N; Dong, AN; Ong, CE; Palanisamy, UD; Pan, Y; Yiap, BC1

Other Studies

6 other study(ies) available for 3-cyano-7-ethoxycoumarin and warfarin

ArticleYear
A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin.
    Analytical biochemistry, 1988, Aug-01, Volume: 172, Issue:2

    Topics: Animals; Autoanalysis; Coumarins; Cytochrome P-450 Enzyme System; Fluorometry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Phenobarbital; Rats; Rats, Inbred F344

1988
Characterization of Clara and type II cells isolated from rat lung by fluorescence-activated flow cytometry.
    The Biochemical journal, 1993, Oct-01, Volume: 295 ( Pt 1)

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Bronchi; Cell Separation; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Epithelial Cells; Epithelium; Flow Cytometry; Fluorescence; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Macrophages; Male; Nitriles; Oxidoreductases; Phosphines; Pyrazoles; Rats; Rats, Inbred F344; Staining and Labeling; Steroid Hydroxylases

1993
3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design.
    Biochemical and biophysical research communications, 2007, Apr-06, Volume: 355, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2C19; Drug Design; Fatty Acids, Monounsaturated; Fluvastatin; Fluvoxamine; Indoles; Ligands; Mixed Function Oxygenases; Models, Molecular; Nitriles; Protein Conformation; Structure-Activity Relationship; Ticlopidine

2007
Evaluation of the effects of 18 non-synonymous single-nucleotide polymorphisms of CYP450 2C19 on in vitro drug inhibition potential by a fluorescence-based high-throughput assay.
    Xenobiotica; the fate of foreign compounds in biological systems, 2011, Volume: 41, Issue:9

    Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP2C19; Fluorescence; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Kinetics; Mutant Proteins; Nitriles; Pharmaceutical Preparations; Polymorphism, Single Nucleotide; Saccharomyces cerevisiae

2011
Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:10

    Topics: Anti-Infective Agents; Catalytic Domain; Chromones; Coumarins; Cryopreservation; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Hepatocytes; Humans; Isoenzymes; Kinetics; Mass Spectrometry; Metabolic Networks and Pathways; Molecular Docking Simulation; Nitriles; Oxazines; Plant Extracts; Polygala; Reproducibility of Results; Substrate Specificity; Time Factors

2012
The Molecular and Enzyme Kinetic Basis for Altered Activity of Three Cytochrome P450 2C19 Variants Found in the Chinese Population.
    Current molecular pharmacology, 2020, Volume: 13, Issue:3

    Topics: Alleles; Amino Acid Sequence; Asian People; Catalytic Domain; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Fluoxetine; Humans; Ketoconazole; Kinetics; Loratadine; Models, Molecular; Molecular Docking Simulation; Mutagenesis, Site-Directed; Nitriles; Omeprazole; Polymorphism, Genetic; Protein Conformation; Protein Isoforms; Recombinant Proteins; Sertraline; Substrate Specificity

2020