3-chloro-4-hydroxyphenylacetic acid and topiramate

3-chloro-4-hydroxyphenylacetic acid has been researched along with topiramate in 2 studies

Compound Research Comparison

Studies (3-chloro-4-hydroxyphenylacetic acid)	Trials (3-chloro-4-hydroxyphenylacetic acid)	Recent Studies (post-2010) (3-chloro-4-hydroxyphenylacetic acid)	Studies (topiramate)	Trials (topiramate)	Recent Studies (post-2010) (topiramate)
13	0	3	3,197	557	1,329

Protein Interaction Comparison

Protein	Taxonomy	topiramate (IC50)
Carbonic anhydrase 1	Homo sapiens (human)	0.25
Carbonic anhydrase 2	Homo sapiens (human)	0.8683
Carbonic anhydrase 2	Rattus norvegicus (Norway rat)	1.4
Carbonic anhydrase 4	Bos taurus (cattle)	0.054

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, RA; Innocenti, A; Poulsen, SA; Supuran, CT	1
Davis, RA; Hall, RA; Hofmann, A; Innocenti, A; Mühlschlegel, FA; Osman, A; Poulsen, SA; Supuran, CT; Vullo, D	1

Other Studies

2 other study(ies) available for 3-chloro-4-hydroxyphenylacetic acid and topiramate

Article	Year
Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library. Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1 Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Humans; Isoenzymes; Mitochondria; Molecular Structure; Phenols; Structure-Activity Relationship	2010
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases. Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6 Topics: Anti-Bacterial Agents; Antifungal Agents; Biological Products; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Cryptococcus neoformans; Crystallography, X-Ray; Humans; Hydrogen Bonding; Isoenzymes; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Phenols; Protein Binding; Small Molecule Libraries	2011

Article

Year

Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.

Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cytosol; Humans; Isoenzymes; Mitochondria; Molecular Structure; Phenols; Structure-Activity Relationship

2010

Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases.

Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6

Topics: Anti-Bacterial Agents; Antifungal Agents; Biological Products; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Catalytic Domain; Cryptococcus neoformans; Crystallography, X-Ray; Humans; Hydrogen Bonding; Isoenzymes; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Phenols; Protein Binding; Small Molecule Libraries

2011