3-aminobenzamide and nu 1025

3-aminobenzamide has been researched along with nu 1025 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Bowman, K; Calvert, AH; Curtin, NJ; Golding, BT; Griffin, RJ; Newell, DR; Pemberton, LC; Srinivasan, S1
Camaioni, E; Costantino, G; Macchiarulo, A; Pellicciari, R1
Almassy, RJ; Boritzki, TJ; Calabrese, CR; Calvert, AH; Curtin, NJ; Ekkers, A; Golding, BT; Griffin, RJ; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, KA; Newell, DR; Thomas, HD; Tikhe, JG; Wang, LZ; Webber, SE; Yu, XH; Zhang, C1
Ferraris, DV1
Battaile, KP; Beletskaya, I; Chirgadze, NY; Gebremeskel, S; Gordon, R; Lam, R; Pai, EF; Qiu, W; Romanov, V; Rottapel, R; Thompson, C; Vodsedalek, J; Voytyuk, O1
Jain, PG; Patel, BD1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chalmers, A; Johnston, P; Joiner, M; Marples, B; Woodcock, M1
Gallmeier, E; Kern, SE1
Haince, JF; Hendzel, MJ; Masson, JY; Poirier, GG; Rouleau, M1

Reviews

3 review(s) available for 3-aminobenzamide and nu 1025

ArticleYear
Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.
    Journal of medicinal chemistry, 2010, Jun-24, Volume: 53, Issue:12

    Topics: Animals; Antineoplastic Agents; Binding Sites; Drug Discovery; Drug Industry; Enzyme Inhibitors; History, 20th Century; History, 21st Century; Humans; Ischemia; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Research

2010
Medicinal chemistry approaches of poly ADP-Ribose polymerase 1 (PARP1) inhibitors as anticancer agents - A recent update.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship

2019
Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy.
    Trends in molecular medicine, 2005, Volume: 11, Issue:10

    Topics: DNA Repair; Gene Components; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Models, Molecular; Neoplasms; Phenanthrenes; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinazolines; Quinazolinones; Signal Transduction

2005

Other Studies

7 other study(ies) available for 3-aminobenzamide and nu 1025

ArticleYear
Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP).
    Journal of medicinal chemistry, 1998, Dec-17, Volume: 41, Issue:26

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cell Survival; Dacarbazine; DNA Repair; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Gamma Rays; Leukemia L1210; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured

1998
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Ligands; Models, Molecular; Naphthalenes; Phenanthridines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Quantitative Structure-Activity Relationship; Quinazolines

2001
Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Antineoplastic Agents; Azepines; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Design; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Models, Molecular; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Topoisomerase I Inhibitors

2004
Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
    Acta crystallographica. Section D, Biological crystallography, 2014, Volume: 70, Issue:Pt 10

    Topics: Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Protein Conformation; Pyrimidinones; Quinazolines; Tankyrases

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation.
    International journal of radiation oncology, biology, physics, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Animals; Benzamides; Cell Line; Cell Line, Tumor; Cell Survival; Cricetinae; Enzyme Inhibitors; Humans; Mice; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Stem Cell Assay

2004
Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition.
    Cancer biology & therapy, 2005, Volume: 4, Issue:7

    Topics: Adenocarcinoma; Apoptosis; Benzamides; BRCA2 Protein; Enzyme Inhibitors; Frameshift Mutation; Humans; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Tumor Cells, Cultured; Tumor Stem Cell Assay

2005