Compounds > 3-aminobenzamide

3-aminobenzamide and 5-aminoisoquinolinone

3-aminobenzamide has been researched along with 5-aminoisoquinolinone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boer, R; Bürkle, A; Eltze, T; Klein, T; McDonald, MC; Thiemermann, C; Wagner, T; Weinbrenner, S1
Battaile, KP; Beletskaya, I; Chirgadze, NY; Gebremeskel, S; Gordon, R; Lam, R; Pai, EF; Qiu, W; Romanov, V; Rottapel, R; Thompson, C; Vodsedalek, J; Voytyuk, O1
Goodfellow, E; Jean-Claude, BJ; Senhaji Mouhri, Z; Williams, C1
Bani, D; Ciampa, A; Cuzzocrea, S; Masini, E; Mazzocca, C; Suzuki, H; Suzuki, Y1
Bramanti, P; Cuzzocrea, S; De Sarro, A; Genovese, T; Mazzon, E; Muià, C; Patel, NS; Thiemermann, C; Threadgill, MD1
Caputi, AP; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Muià, C; Thiemermann, C; Threadgill, MD1
Holt, A; Kandasamy, AD; Nicolescu, AC; Pacher, P; Schulz, R1
Bakkalbasi, E; Brown, RW; Burgess, KC; Chandley, MJ; Crawford, JD; Hernandez, LJ; Miller, C; Ordway, GA; Szebeni, A; Szebeni, K1

Other Studies

8 other study(ies) available for 3-aminobenzamide and 5-aminoisoquinolinone

ArticleYear
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridines; Quinolones; Rats; Rats, Wistar; Recombinant Proteins; Solubility; Structure-Activity Relationship

2008
Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
    Acta crystallographica. Section D, Biological crystallography, 2014, Volume: 70, Issue:Pt 10

    Topics: Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Protein Conformation; Pyrimidinones; Quinazolines; Tankyrases

2014
Design, synthesis and biological activity of novel molecules designed to target PARP and DNA.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: Animals; Binding Sites; BRCA2 Protein; CHO Cells; Cricetinae; Cricetulus; DNA; DNA Damage; Drug Design; Enzyme Activation; Molecular Docking Simulation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Structure, Tertiary

2017
Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3

    Topics: Allergens; Animals; Anti-Asthmatic Agents; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Enzyme Inhibitors; Guinea Pigs; Immunohistochemistry; Isoquinolines; Lung; Male; Malondialdehyde; Mast Cells; Nitric Oxide; Ovalbumin; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Respiratory Mechanics; Tumor Necrosis Factor-alpha; Tyrosine

2004
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Animals; Apoptosis; Benzamides; Blotting, Western; Cell Nucleus; Densitometry; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; I-kappa B Proteins; In Situ Nick-End Labeling; Isoquinolines; Male; Mice; Neutrophils; NF-kappa B; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Signal Transduction; Spinal Cord; Spinal Cord Injuries

2005
Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 313, Issue:2

    Topics: Animals; Benzamides; Bleomycin; Enzyme Inhibitors; Isoquinolines; Male; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Respiratory Distress Syndrome; Signal Transduction

2005
Inhibition of matrix metalloproteinase-2 by PARP inhibitors.
    Biochemical and biophysical research communications, 2009, Oct-02, Volume: 387, Issue:4

    Topics: Benzamides; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoquinolines; Matrix Metalloproteinase Inhibitors; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Zinc

2009
Antidepressant-Like Actions of Inhibitors of Poly(ADP-Ribose) Polymerase in Rodent Models.
    The international journal of neuropsychopharmacology, 2017, 12-01, Volume: 20, Issue:12

    Topics: Animals; Antidepressive Agents; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Fluoxetine; Food Preferences; Immobility Response, Tonic; Interpersonal Relations; Isoquinolines; Male; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Reaction Time; Stress, Psychological; Sucrose; Swimming

2017