Compounds > 3-aminobenzamide

3-aminobenzamide and 4-hydroxyquinazoline

3-aminobenzamide has been researched along with 4-hydroxyquinazoline in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Camaioni, E; Costantino, G; Macchiarulo, A; Pellicciari, R1
Boer, R; Bürkle, A; Eltze, T; Klein, T; McDonald, MC; Thiemermann, C; Wagner, T; Weinbrenner, S1
Ferraris, DV1
Kulkarni, SS; Low, WK; Shah, JR; Singh, S; Talele, TT1
Battaile, KP; Beletskaya, I; Chirgadze, NY; Gebremeskel, S; Gordon, R; Lam, R; Pai, EF; Qiu, W; Romanov, V; Rottapel, R; Thompson, C; Vodsedalek, J; Voytyuk, O1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Lee, YJ; Shacter, E2

Reviews

1 review(s) available for 3-aminobenzamide and 4-hydroxyquinazoline

ArticleYear
Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic.
    Journal of medicinal chemistry, 2010, Jun-24, Volume: 53, Issue:12

    Topics: Animals; Antineoplastic Agents; Binding Sites; Drug Discovery; Drug Industry; Enzyme Inhibitors; History, 20th Century; History, 21st Century; Humans; Ischemia; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Research

2010

Other Studies

7 other study(ies) available for 3-aminobenzamide and 4-hydroxyquinazoline

ArticleYear
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Ligands; Models, Molecular; Naphthalenes; Phenanthridines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Quantitative Structure-Activity Relationship; Quinazolines

2001
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridines; Quinolones; Rats; Rats, Wistar; Recombinant Proteins; Solubility; Structure-Activity Relationship

2008
Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors.
    European journal of medicinal chemistry, 2012, Volume: 50

    Topics: Animals; BRCA1 Protein; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship

2012
Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
    Acta crystallographica. Section D, Biological crystallography, 2014, Volume: 70, Issue:Pt 10

    Topics: Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Protein Conformation; Pyrimidinones; Quinazolines; Tankyrases

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Oxidative stress inhibits apoptosis in human lymphoma cells.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Adenosine Triphosphate; Annexin A5; Apoptosis; Benzamides; Burkitt Lymphoma; Calcimycin; Caspase Inhibitors; Caspases; DNA Fragmentation; Etoposide; Humans; Hydrogen Peroxide; Oligomycins; Oxidative Stress; Protein Binding; Quinazolines; Quinazolinones; Tumor Cells, Cultured

1999
Hydrogen peroxide inhibits activation, not activity, of cellular caspase-3 in vivo.
    Free radical biology & medicine, 2000, Oct-01, Volume: 29, Issue:7

    Topics: Adenosine Triphosphate; Apoptosis; Benzamides; Burkitt Lymphoma; Caspase 3; Caspases; Coumarins; Enzyme Activation; Humans; Hydrogen Peroxide; Oligopeptides; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Quinazolinones; Recombinant Proteins; Serine Proteinase Inhibitors; Tumor Cells, Cultured

2000