3-aminobenzamide and 3,4-dihydro-5-methyl-1(2h)-isoquinolinone

3-aminobenzamide has been researched along with 3,4-dihydro-5-methyl-1(2h)-isoquinolinone in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowman, K; Calvert, AH; Curtin, NJ; Golding, BT; Griffin, RJ; Newell, DR; Pemberton, LC; Srinivasan, S1
Camaioni, E; Costantino, G; Macchiarulo, A; Pellicciari, R1
Almassy, RJ; Boritzki, TJ; Calabrese, CR; Calvert, AH; Curtin, NJ; Ekkers, A; Golding, BT; Griffin, RJ; Hostomsky, Z; Kumpf, RA; Kyle, S; Li, J; Maegley, KA; Newell, DR; Thomas, HD; Tikhe, JG; Wang, LZ; Webber, SE; Yu, XH; Zhang, C1
Jain, PG; Patel, BD1
Arundel-Suto, CM; Scavone, SV; Sebolt-Leopold, JS; Suto, MJ; Turner, WR1
Berger, NA; Berger, RB; Berger, SJ; Chatterjee, S; Cheng, MF1
Elliot, T; Lalonde, C; Yau, L; Zahradka, P1
Linning, KD; Olson, LK; Szabo, C; Tai, MH; Ye, DZ1

Reviews

1 review(s) available for 3-aminobenzamide and 3,4-dihydro-5-methyl-1(2h)-isoquinolinone

ArticleYear
Medicinal chemistry approaches of poly ADP-Ribose polymerase 1 (PARP1) inhibitors as anticancer agents - A recent update.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship

2019

Other Studies

7 other study(ies) available for 3-aminobenzamide and 3,4-dihydro-5-methyl-1(2h)-isoquinolinone

ArticleYear
Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP).
    Journal of medicinal chemistry, 1998, Dec-17, Volume: 41, Issue:26

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cell Survival; Dacarbazine; DNA Repair; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Gamma Rays; Leukemia L1210; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured

1998
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Ligands; Models, Molecular; Naphthalenes; Phenanthridines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Quantitative Structure-Activity Relationship; Quinazolines

2001
Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase.
    Journal of medicinal chemistry, 2004, Oct-21, Volume: 47, Issue:22

    Topics: Antineoplastic Agents; Azepines; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Design; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Models, Molecular; Poly(ADP-ribose) Polymerase Inhibitors; Structure-Activity Relationship; Topoisomerase I Inhibitors

2004
Effect of PD 128763, a new potent inhibitor of poly(ADP-ribose) polymerase, on X-ray-induced cellular recovery processes in Chinese hamster V79 cells.
    Radiation research, 1991, Volume: 126, Issue:3

    Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Isoquinolines; Poly(ADP-ribose) Polymerase Inhibitors

1991
Effect of inhibitors of poly(ADP-ribose) polymerase on the induction of GRP78 and subsequent development of resistance to etoposide.
    Cancer research, 1995, Feb-15, Volume: 55, Issue:4

    Topics: 6-Aminonicotinamide; Animals; Benzamides; Carrier Proteins; Cricetinae; Cricetulus; Drug Resistance; Endoplasmic Reticulum Chaperone BiP; Etoposide; Heat-Shock Proteins; Isoquinolines; Molecular Chaperones; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Substance Withdrawal Syndrome; Transcription, Genetic

1995
Repression of phosphoenolpyruvate carboxykinase gene activity by insulin is blocked by 3-aminobenzamide but not by PD128763, a selective inhibitor of poly(ADP-ribose) polymerase.
    European journal of biochemistry, 1998, Apr-01, Volume: 253, Issue:1

    Topics: ADP Ribose Transferases; Animals; Benzamides; Cell Division; Cyclic AMP; Enzyme Inhibitors; Gene Expression; Insulin; Isoquinolines; Phosphoenolpyruvate Carboxykinase (GTP); Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Rats; RNA, Messenger; Thionucleotides; Tumor Cells, Cultured

1998
MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
    Diabetes, 2006, Volume: 55, Issue:3

    Topics: Antioxidants; Benzamides; Cells, Cultured; Enzyme Inhibitors; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Isoquinolines; Maf Transcription Factors, Large; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Promoter Regions, Genetic; RNA, Messenger; Trans-Activators

2006