3-aminobenzamide and 1,5-dihydroxyisoquinoline

3-aminobenzamide has been researched along with 1,5-dihydroxyisoquinoline in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's10 (58.82)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Camaioni, E; Costantino, G; Macchiarulo, A; Pellicciari, R1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Boer, R; Bürkle, A; Eltze, T; Klein, T; McDonald, MC; Thiemermann, C; Wagner, T; Weinbrenner, S1
Battaile, KP; Beletskaya, I; Chirgadze, NY; Gebremeskel, S; Gordon, R; Lam, R; Pai, EF; Qiu, W; Romanov, V; Rottapel, R; Thompson, C; Vodsedalek, J; Voytyuk, O1
Aupeix, K; Bischoff, P; Dufour, P; Marchal, J; Oth, D; Picard, V; Varin, M; Weltin, D1
Hinds, CJ; Thiemermann, C; Wray, GM1
Bowes, J; McDonald, MC; Piper, J; Thiemermann, C1
Chatterjee, PK; Cuzzocrea, S; Thiemermann, C1
Thies, RL; Walisser, JA1
Filipe, HM; McDonald, MC; Thiemermann, C1
Berry, DM; Meckling-Gill, KA; Williams, K1
Chatterjee, PK; Cuzzocrea, S; Otto, M; Thiemermann, C; Zacharowski, K1
Akbay, E; Atik, U; Bozlu, M; Canpolat, B; Cayan, S; Eskandari, G1
Abatan, OI; Komjáti, K; Minchenko, AG; Obrosova, IG; Pacher, P; Stevens, MJ; Szabó, C; White, L1
Frank, RN; Minchenko, AG; Obrosova, IG; Pacher, P; Seigel, GM; Stevens, MJ; Szabó, C; Zsengeller, Z1
Hake, PW; Kaplan, J; O'Connor, M; Zingarelli, B1
Gebska, A; Jakubowski, A; Jawień, J; Korbut, R; Olszanecki, R1

Other Studies

17 other study(ies) available for 3-aminobenzamide and 1,5-dihydroxyisoquinoline

ArticleYear
Modeling of poly(ADP-ribose)polymerase (PARP) inhibitors. Docking of ligands and quantitative structure-activity relationship analysis.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Ligands; Models, Molecular; Naphthalenes; Phenanthridines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Binding; Quantitative Structure-Activity Relationship; Quinazolines

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Imidazoquinolinone, imidazopyridine, and isoquinolindione derivatives as novel and potent inhibitors of the poly(ADP-ribose) polymerase (PARP): a comparison with standard PARP inhibitors.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Animals; Cell Line; Cell Line, Tumor; Fibroblasts; Humans; Imidazoles; Isoquinolines; Kinetics; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridines; Quinolones; Rats; Rats, Wistar; Recombinant Proteins; Solubility; Structure-Activity Relationship

2008
Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
    Acta crystallographica. Section D, Biological crystallography, 2014, Volume: 70, Issue:Pt 10

    Topics: Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Protein Conformation; Pyrimidinones; Quinazolines; Tankyrases

2014
Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor.
    International journal of immunopharmacology, 1995, Volume: 17, Issue:4

    Topics: Acridines; Acridones; Animals; Benzamides; Cells, Cultured; Concanavalin A; Female; Gamma Rays; Immunosuppressive Agents; Interleukin-2; Isoquinolines; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Spleen; T-Lymphocytes, Cytotoxic

1995
Effects of inhibitors of poly(ADP-ribose) synthetase activity on hypotension and multiple organ dysfunction caused by endotoxin.
    Shock (Augusta, Ga.), 1998, Volume: 10, Issue:1

    Topics: Animals; Benzamides; Endotoxemia; Enzyme Inhibitors; Hemodynamics; Hypotension; Isoquinolines; Kidney; Lactic Acid; Liver; Male; Multiple Organ Failure; Niacinamide; Nitrates; Nitrites; Pancreas; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Succimer

1998
Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress.
    Cardiovascular research, 1999, Volume: 41, Issue:1

    Topics: Aminobenzoates; Animals; Benzamides; Cell Death; Cell Line; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoquinolines; Male; meta-Aminobenzoates; Myocardial Reperfusion Injury; Niacin; Niacinamide; Oxidative Stress; Perfusion; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar

1999
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.
    Kidney international, 1999, Volume: 56, Issue:3

    Topics: Animals; Benzamides; Catalase; Cells, Cultured; Deferoxamine; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Isoquinolines; Kidney Tubules, Proximal; L-Lactate Dehydrogenase; Necrosis; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Rats

1999
Poly(ADP-ribose) polymerase inhibition in oxidant-stressed endothelial cells prevents oncosis and permits caspase activation and apoptosis.
    Experimental cell research, 1999, Sep-15, Volume: 251, Issue:2

    Topics: Animals; Apoptosis; Aurintricarboxylic Acid; Benzamides; Caspase 3; Caspases; Cattle; Cell Death; Cell Membrane; Cells, Cultured; Cycloheximide; Endothelium, Vascular; Energy Metabolism; Enzyme Activation; Hydrogen Peroxide; Inflammation; Isoquinolines; Oxidants; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors

1999
Effects of inhibitors of the activity of poly (ADP-ribose) synthetase on the organ injury and dysfunction caused by haemorrhagic shock.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Blood Pressure; Creatine Kinase; Creatinine; Enzyme Inhibitors; Heart Rate; Ischemia; Isoquinolines; Kidney; Kidney Diseases; Lipase; Liver; Liver Diseases; Male; Niacinamide; Pancreas; Pancreatic Diseases; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Shock, Hemorrhagic; Syndrome; Urea

1999
All trans retinoic acid induces apoptosis in acute promyelocytic NB4 cells when combined with isoquinolinediol, a poly(ADP-ribose) polymerase inhibitor.
    Leukemia research, 2000, Volume: 24, Issue:4

    Topics: Apoptosis; Benzamides; Calcitriol; Cell Differentiation; Cell Division; DNA Fragmentation; Enzyme Inhibitors; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Poly(ADP-ribose) Polymerase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Quinolines; Tretinoin

2000
Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:5

    Topics: Anesthesia; Animals; Benzamides; Creatinine; Enzyme Inhibitors; Glomerular Filtration Rate; Isoquinolines; Kidney; Male; Natriuresis; Niacinamide; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Urea

2000
The effect of poly (adenosine diphosphate-ribose) polymerase inhibitors on biochemical changes in testicular ischemia-reperfusion injury.
    The Journal of urology, 2003, Volume: 169, Issue:5

    Topics: 1-Naphthylamine; Animals; Benzamides; Isoquinolines; Male; Naphthalimides; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Quinolones; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Testis

2003
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:11

    Topics: Animals; Benzamides; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Isoquinolines; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Models, Biological; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger

2003
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.
    International journal of molecular medicine, 2004, Volume: 14, Issue:1

    Topics: Animals; Benzamides; Cell Hypoxia; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme Inhibitors; Humans; Immunochemistry; Isoquinolines; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Pigment Epithelium of Eye; Poly(ADP-ribose) Polymerase Inhibitors; Quinolines; Rats; Rats, Wistar; Retina; RNA, Messenger; Sorbitol; Up-Regulation; Vascular Endothelial Growth Factors

2004
Inhibitors of poly (ADP-ribose) polymerase ameliorate myocardial reperfusion injury by modulation of activator protein-1 and neutrophil infiltration.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:3

    Topics: Animals; Benzamides; Caspase 3; Caspases; Cell Adhesion Molecules; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Isoquinolines; Male; Myocardial Reperfusion Injury; Neutrophils; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Transcription Factor AP-1

2005
Inhibition of NOS-2 induction in LPS-stimulated J774.2 cells by 1, 5-isoquinolinediol, an inhibitor of PARP.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57, Issue:1

    Topics: Animals; Benzamides; Cell Line; Cell Respiration; Enzyme Inhibitors; Isoquinolines; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase Type II; Nitrites; Poly(ADP-ribose) Polymerase Inhibitors; Quinolines

2006