Compounds > 3-amino-6-methyl-5-phenyl-2(1h)-pyridinone
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3-amino-6-methyl-5-phenyl-2(1h)-pyridinone and milrinone

3-amino-6-methyl-5-phenyl-2(1h)-pyridinone has been researched along with milrinone in 2 studies

Compound Research Comparison

Studies
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)		Trials
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)		Recent Studies (post-2010)
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)		Studies
(milrinone)		Trials
(milrinone)		Recent Studies (post-2010) (milrinone)
11001,605235452

Protein Interaction Comparison

ProteinTaxonomy3-amino-6-methyl-5-phenyl-2(1h)-pyridinone (IC50)milrinone (IC50)
Phosphodiesterase Bos taurus (cattle)1
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.3
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)0.3
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.52
Prostaglandin G/H synthase 1Homo sapiens (human)4.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)6
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)6
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)6
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)3.15
cGMP-inhibited 3',5'-cyclic phosphodiesterase BHomo sapiens (human)1.8674
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)1.8177
cGMP-specific 3',5'-cyclic phosphodiesteraseBos taurus (cattle)5
Phosphodiesterase Sus scrofa (pig)0.843

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erhardt, PW1
Herzig, JW; Quast, U1

Reviews

1 review(s) available for 3-amino-6-methyl-5-phenyl-2(1h)-pyridinone and milrinone

ArticleYear
In search of the digitalis replacement.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship

1987

Other Studies

1 other study(ies) available for 3-amino-6-methyl-5-phenyl-2(1h)-pyridinone and milrinone

ArticleYear
On the role of Ca++ binding proteins as possible targets for Ca++ sensitizing agents.
    Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4

    Topics: Amrinone; Animals; Bepridil; Calcium; Calcium-Binding Proteins; Calmodulin; Cardiotonic Agents; Dose-Response Relationship, Drug; Milrinone; Models, Cardiovascular; Myocardial Contraction; Piperazines; Pyridones; Swine; Trifluoperazine; Troponin; Troponin C

1992