Page last updated: 2024-09-04

3-amino-6-methyl-5-phenyl-2(1h)-pyridinone and bepridil

3-amino-6-methyl-5-phenyl-2(1h)-pyridinone has been researched along with bepridil in 1 studies

*Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. [MeSH]

*Bepridil: A long-acting calcium-blocking agent with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. [MeSH]

Compound Research Comparison

Studies
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)
Trials
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)
Recent Studies (post-2010)
(3-amino-6-methyl-5-phenyl-2(1h)-pyridinone)
Studies
(bepridil)
Trials
(bepridil)
Recent Studies (post-2010) (bepridil)
11007987094

Protein Interaction Comparison

ProteinTaxonomy3-amino-6-methyl-5-phenyl-2(1h)-pyridinone (IC50)bepridil (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)1.4
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1
Lethal factorBacillus anthracis4.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.5184
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.2
Sodium channel protein type 5 subunit alphaHomo sapiens (human)3.7

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herzig, JW; Quast, U1

Other Studies

1 other study(ies) available for 3-amino-6-methyl-5-phenyl-2(1h)-pyridinone and bepridil

ArticleYear
On the role of Ca++ binding proteins as possible targets for Ca++ sensitizing agents.
    Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4

    Topics: Amrinone; Animals; Bepridil; Calcium; Calcium-Binding Proteins; Calmodulin; Cardiotonic Agents; Dose-Response Relationship, Drug; Milrinone; Models, Cardiovascular; Myocardial Contraction; Piperazines; Pyridones; Swine; Trifluoperazine; Troponin; Troponin C

1992