Compounds > 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile

3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile and benzonitrile

3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile has been researched along with benzonitrile* in 1 studies

Other Studies

1 other study(ies) available for 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile and benzonitrile

Article	Year
Optimization of [11C]DASB-synthesis: vessel-based and flow-through microreactor methods. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:11 The intention for the present study was to implement a microfluidic set-up for N-(11)C-methylations in a flow-through microreactor device with [(11)C]DASB as model-compound and [(11)C]CH(3)I and [(11)C]CH(3)OTf, respectively, as (11)C-methylation agents. Due to an observed "aging" effect of the (11)C-methylation agents' solution, this goal was not achieved. Nevertheless, based on these observations, the time consumption for the vessel-based routine production of [(11)C]DASB was reduced (34±1 min) and RCY was increased to 45.1±4.6% (EOB; 5.2±0.95 GBq EOS). Topics: Aniline Compounds; Carbon Radioisotopes; Isotope Labeling; Methylation; Microfluidics; Nitriles; Positron-Emission Tomography; Radiopharmaceuticals; Sulfides	2012

Article

Year

Optimization of [11C]DASB-synthesis: vessel-based and flow-through microreactor methods.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:11

The intention for the present study was to implement a microfluidic set-up for N-(11)C-methylations in a flow-through microreactor device with [(11)C]DASB as model-compound and [(11)C]CH(3)I and [(11)C]CH(3)OTf, respectively, as (11)C-methylation agents. Due to an observed "aging" effect of the (11)C-methylation agents' solution, this goal was not achieved. Nevertheless, based on these observations, the time consumption for the vessel-based routine production of [(11)C]DASB was reduced (34±1 min) and RCY was increased to 45.1±4.6% (EOB; 5.2±0.95 GBq EOS).

Topics: Aniline Compounds; Carbon Radioisotopes; Isotope Labeling; Methylation; Microfluidics; Nitriles; Positron-Emission Tomography; Radiopharmaceuticals; Sulfides

2012