Page last updated: 2024-09-04

3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine and sch 28080

3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine has been researched along with sch 28080 in 4 studies

Compound Research Comparison

Studies
(3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine)
Trials
(3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine)
Recent Studies (post-2010)
(3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine)
Studies
(sch 28080)
Trials
(sch 28080)
Recent Studies (post-2010) (sch 28080)
800217020

Protein Interaction Comparison

ProteinTaxonomy3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine (IC50)sch 28080 (IC50)
Cytochrome P450 1A2Homo sapiens (human)2
Cytochrome P450 3A4Homo sapiens (human)9

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elm, G; Helander, HF; Mattsson, H; Ottosson, S1
Beil, W; Sewing, KF; Staar, U1
Scott, CK; Sundell, E1
Castrovilly, L; Scott, CK; Sundell, E1

Other Studies

4 other study(ies) available for 3-amino-2-methyl-8-phenylmethoxyimidazo(1,2-a)pyrazine and sch 28080

ArticleYear
Structure and function of rat parietal cells during treatment with omeprazole, SCH 28080, SCH 32651, or ranitidine.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Pyrazines; Ranitidine; Rats; Rats, Inbred Strains; Time Factors

1990
SCH 28080 is a more selective inhibitor than SCH 32651 at the K+ site of gastric K+/H+-ATPase.
    European journal of pharmacology, 1987, Jul-23, Volume: 139, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Dogs; Gastric Mucosa; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; Imidazoles; In Vitro Techniques; Kidney; Kinetics; Potassium; Pyrazines; Sodium-Potassium-Exchanging ATPase

1987
Inhibition of H+K+ATPase by SCH 28080 and SCH 32651.
    European journal of pharmacology, 1985, Jun-07, Volume: 112, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Imidazoles; In Vitro Techniques; Microsomes; Pyrazines; Rabbits

1985
Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
    Biochemical pharmacology, 1987, Jan-01, Volume: 36, Issue:1

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Bucladesine; Dithiothreitol; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Mercaptoethanol; Microsomes; Omeprazole; Pyrazines; Rabbits

1987