Page last updated: 2024-09-03

3-amino-2-hydroxy-4-phenylbutanoic acid and lopinavir

3-amino-2-hydroxy-4-phenylbutanoic acid has been researched along with lopinavir in 1 studies

Compound Research Comparison

Studies
(3-amino-2-hydroxy-4-phenylbutanoic acid)
Trials
(3-amino-2-hydroxy-4-phenylbutanoic acid)
Recent Studies (post-2010)
(3-amino-2-hydroxy-4-phenylbutanoic acid)
Studies
(lopinavir)
Trials
(lopinavir)
Recent Studies (post-2010) (lopinavir)
42032,3834991,358

Protein Interaction Comparison

ProteinTaxonomy3-amino-2-hydroxy-4-phenylbutanoic acid (IC50)lopinavir (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)1.7
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 29.12
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.035
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)8.5114
Protease Human immunodeficiency virus 10.025
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.6
Protease Human immunodeficiency virus 10.0175

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adachi, M; Hayashi, Y; Hidaka, K; Kameoka, M; Kempf, DJ; Kimura, T; Kiso, Y; Kuroki, R; McDaniel, KF; Nguyen, JT; Sankaranarayanan, R; Wang, J1

Other Studies

1 other study(ies) available for 3-amino-2-hydroxy-4-phenylbutanoic acid and lopinavir

ArticleYear
Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.
    Journal of medicinal chemistry, 2018, 06-28, Volume: 61, Issue:12

    Topics: Crystallography, X-Ray; Darunavir; Drug Resistance, Viral; Glycine; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Lopinavir; Peptidomimetics; Phenylbutyrates; Serum; Structure-Activity Relationship

2018