3-amino-2-hydroxy-4-phenylbutanoic acid has been researched along with kynostatin 272 in 6 studies
| Studies (3-amino-2-hydroxy-4-phenylbutanoic acid) | Trials (3-amino-2-hydroxy-4-phenylbutanoic acid) | Recent Studies (post-2010) (3-amino-2-hydroxy-4-phenylbutanoic acid) | Studies (kynostatin 272) | Trials (kynostatin 272) | Recent Studies (post-2010) (kynostatin 272) |
|---|---|---|---|---|---|
| 42 | 0 | 3 | 58 | 3 | 3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erickson, J; Ford, H; Gulnik, S; Hayashi, H; Kageyama, S; Mimoto, T; Murakawa, Y; Nomizu, M; Shirasaka, T; Takada, K | 1 |
| Baldwin, ET; Bhat, TN; Erickson, JW; Gulnik, S; Kiso, Y; Liu, B; Mitsuya, H | 1 |
| Baldwin, ET; Bhat, TN; Erickson, JW; Gulnik, S; Kiso, Y; Liu, B; Mimoto, T; Mitsuya, H; Topol, IA | 1 |
| Kiso, Y | 1 |
| Itoh, E; Shibata, N; Terashima, S | 1 |
| Erickson, J; Falloon, J; Hayashi, H; Kato, R; Kavlick, MF; Maroun, V; Masur, H; Mimoto, T; Mitsuya, H; Nguyen, A; Shintani, M; Ueno, T; Yoshimura, K; Yusa, K | 1 |
1 review(s) available for 3-amino-2-hydroxy-4-phenylbutanoic acid and kynostatin 272
| Article | Year |
|---|---|
Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere.
Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Animals; Antiviral Agents; Binding Sites; Drug Design; HIV Protease; HIV Protease Inhibitors; Humans; Molecular Sequence Data; Oligopeptides; Phenylbutyrates | 1996 |
5 other study(ies) available for 3-amino-2-hydroxy-4-phenylbutanoic acid and kynostatin 272
| Article | Year |
|---|---|
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine.
Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Drug Resistance, Microbial; Gene Products, gag; HIV; HIV Protease Inhibitors; HIV-1; HIV-2; Humans; Oligopeptides; Phenylbutyrates; Protein Precursors; Protein Processing, Post-Translational; Radioimmunoprecipitation Assay; Zidovudine | 1993 |
Structure of HIV-1 protease with KNI-272: a transition state mimetic inhibitor containing allophenylnorstatine.
Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; HIV Protease; HIV Protease Inhibitors; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Oligopeptides; Phenylbutyrates; Protein Conformation | 1995 |
Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophenylnorstatine.
Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; Hydrogen; Molecular Sequence Data; Oligopeptides; Phenylbutyrates; Proline; Protein Conformation; Structure-Activity Relationship; Water | 1995 |
Practical synthesis of (2s,3s)-3-amino-2-hydroxy-4-phenylbutyric acid, a key component of HIV protease inhibitors.
Topics: Anti-HIV Agents; Carbamates; Furans; HIV Protease Inhibitors; Nitriles; Oligopeptides; Phenylbutyrates; Stereoisomerism; Sulfonamides | 1998 |
JE-2147: a dipeptide protease inhibitor (PI) that potently inhibits multi-PI-resistant HIV-1.
Topics: Adult; Amino Acid Sequence; Anti-HIV Agents; Cell Line; Cloning, Molecular; Dipeptides; Drug Design; Drug Resistance; HIV Protease; HIV Protease Inhibitors; Humans; Male; Middle Aged; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Oligopeptides; Phenylbutyrates; Reverse Transcriptase Inhibitors | 1999 |